Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   LDO10_RS01515 Genome accession   NZ_AP024929
Coordinates   261419..262423 (-) Length   334 a.a.
NCBI ID   WP_143584529.1    Uniprot ID   A0AAD1NWB8
Organism   Thermus thermophilus strain AA2-2     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 256419..267423
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LDO10_RS01480 (TthAA22_02850) hisG 256891..257511 (+) 621 WP_060384772.1 ATP phosphoribosyltransferase -
  LDO10_RS01485 (TthAA22_02860) trmH 257508..258092 (+) 585 WP_143584516.1 tRNA (guanosine(18)-2'-O)-methyltransferase TrmH -
  LDO10_RS01490 (TthAA22_02870) - 258082..258321 (-) 240 WP_008630920.1 hypothetical protein -
  LDO10_RS01495 (TthAA22_02880) - 258323..258511 (-) 189 WP_038034982.1 hypothetical protein -
  LDO10_RS01500 (TthAA22_02890) - 258501..259457 (-) 957 WP_143584518.1 branched-chain amino acid transaminase -
  LDO10_RS01505 (TthAA22_02900) - 259444..260397 (-) 954 WP_143584522.1 hydrogen peroxide-inducible genes activator -
  LDO10_RS01510 (TthAA22_02910) - 260507..261415 (+) 909 WP_143584525.1 manganese catalase family protein -
  LDO10_RS01515 (TthAA22_02920) dprA 261419..262423 (-) 1005 WP_143584529.1 DNA-processing protein DprA Machinery gene
  LDO10_RS01520 (TthAA22_02930) era 262508..263413 (+) 906 WP_008630929.1 GTPase Era -
  LDO10_RS01525 (TthAA22_02940) - 263458..264345 (+) 888 WP_143584533.1 acyltransferase -
  LDO10_RS01535 (TthAA22_02950) - 264541..265515 (+) 975 WP_143584535.1 bifunctional oligoribonuclease/PAP phosphatase NrnA -
  LDO10_RS01540 (TthAA22_02960) - 265493..266041 (-) 549 WP_223965896.1 Uma2 family endonuclease -
  LDO10_RS01545 (TthAA22_02970) - 266051..267271 (-) 1221 WP_143584541.1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase -

Sequence

Protein


Download         Length: 334 a.a.        Molecular weight: 35982.73 Da        Isoelectric Point: 6.1789

>NTDB_id=89495 LDO10_RS01515 WP_143584529.1 261419..262423(-) (dprA) [Thermus thermophilus strain AA2-2]
MDPLALALLPGIGPKRLLEVLKAEDPLGFLRERFPEAWRHLPEAEAQAERERGRAEALGVRILGLWEEGFPEGLKALPQP
PTHLYLKGELPPEREAVALVGTRRASPWALAFARRLARELSEAGLWVVSGLARGIDREAHLGALEAGGRTLGVLGSALDR
VYPPENRPLAQRMDLLSEFPFGTGPKPEFFPRRNRLIAGLSRAVVVVEAPLDSGALITARHALELGKEVLAVPGRPTDER
SLGANRLIQDGAYPVLSAEDVLAYLGVAARPKPLPGLSPEEEALYALLQEKGEALPEALAMALGIPPERVLSLLTLLELK
GLARALPGGRYGPG

Nucleotide


Download         Length: 1005 bp        

>NTDB_id=89495 LDO10_RS01515 WP_143584529.1 261419..262423(-) (dprA) [Thermus thermophilus strain AA2-2]
GTGGACCCCTTGGCCCTCGCCCTCCTCCCGGGCATCGGCCCCAAGCGGCTTTTGGAGGTCCTAAAGGCGGAGGACCCTCT
GGGCTTCCTGCGGGAGCGCTTCCCCGAGGCCTGGCGGCACCTCCCCGAGGCCGAGGCCCAGGCGGAAAGGGAAAGGGGGC
GCGCCGAGGCCCTGGGGGTGCGCATCCTGGGCCTCTGGGAGGAGGGCTTCCCCGAGGGTCTGAAGGCGCTTCCCCAGCCG
CCCACCCACCTCTACCTGAAGGGGGAGCTTCCCCCGGAAAGGGAGGCGGTGGCCCTCGTGGGCACGCGCCGGGCCTCTCC
TTGGGCCTTGGCCTTTGCCCGGAGGCTCGCCCGGGAGCTTTCCGAGGCCGGGCTTTGGGTGGTCTCGGGCCTCGCCCGGG
GCATAGACCGGGAGGCCCACCTCGGGGCCCTCGAGGCCGGGGGGCGCACCCTGGGCGTCCTGGGAAGCGCCCTGGACCGG
GTCTACCCCCCGGAAAACCGCCCTTTGGCCCAACGGATGGACCTCCTCTCCGAGTTCCCCTTCGGGACCGGCCCTAAGCC
CGAGTTCTTTCCCCGGCGGAACCGCCTCATCGCCGGGCTCTCCCGGGCGGTGGTCGTGGTGGAGGCCCCCCTGGACTCCG
GGGCCCTCATCACCGCCCGCCACGCCTTGGAGCTCGGCAAGGAGGTGCTGGCCGTCCCCGGAAGGCCCACGGACGAGCGT
TCCCTGGGGGCCAACCGCCTCATCCAGGACGGGGCCTACCCGGTGCTCTCCGCCGAGGACGTCCTTGCCTACCTGGGGGT
GGCCGCAAGGCCCAAACCCCTCCCGGGCCTCTCCCCGGAGGAGGAGGCCCTTTACGCCCTCCTGCAGGAAAAGGGGGAGG
CGCTCCCCGAGGCCCTGGCCATGGCCCTGGGGATCCCCCCGGAGCGGGTGCTCTCCCTCCTCACCCTCTTGGAGCTAAAG
GGCCTGGCCCGGGCCCTCCCGGGAGGGCGCTACGGGCCAGGCTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(56-255)

DprA winged helix domain (DprA_WH)

(268-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Thermus thermophilus HB27

97.305

100

0.973
  dprA Vibrio campbellii strain DS40M4

38.547

100

0.413
  dprA Vibrio cholerae strain A1552

37.569

100

0.407
  dprA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

45.548

87.425

0.398
  dprA Neisseria meningitidis strain C311

37.425

100

0.374
  dprA Neisseria meningitidis MC58

37.425

100

0.374

Multiple sequence alignment