Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   RJ559_RS04770 Genome accession   NZ_CP134395
Coordinates   1002894..1004678 (+) Length   594 a.a.
NCBI ID   WP_310957228.1    Uniprot ID   -
Organism   Helicobacter pylori strain ICDC15003-8-2     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 997894..1009678
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJ559_RS04740 (RJ559_04740) motB 998662..999435 (+) 774 WP_310957225.1 flagellar motor protein MotB -
  RJ559_RS04745 (RJ559_04745) - 999432..999878 (+) 447 WP_001081241.1 hypothetical protein -
  RJ559_RS04750 (RJ559_04750) - 999947..1001606 (+) 1660 Protein_932 ABC transporter permease/substrate-binding protein -
  RJ559_RS04755 (RJ559_04755) - 1001608..1002258 (+) 651 WP_310957226.1 ABC transporter ATP-binding protein -
  RJ559_RS04760 (RJ559_04760) - 1002261..1002440 (-) 180 WP_000468791.1 hypothetical protein -
  RJ559_RS04765 (RJ559_04765) - 1002432..1002893 (+) 462 WP_310957227.1 hypothetical protein -
  RJ559_RS04770 (RJ559_04770) uvrC 1002894..1004678 (+) 1785 WP_310957228.1 excinuclease ABC subunit UvrC Machinery gene
  RJ559_RS04775 (RJ559_04775) - 1004689..1005954 (+) 1266 WP_310957229.1 homoserine dehydrogenase -
  RJ559_RS04780 (RJ559_04780) - 1005954..1006298 (+) 345 WP_001211673.1 YraN family protein -
  RJ559_RS04785 (RJ559_04785) trxA 1006387..1006707 (+) 321 WP_000020199.1 thioredoxin -
  RJ559_RS04790 (RJ559_04790) trxB 1006713..1007648 (+) 936 WP_000564430.1 thioredoxin-disulfide reductase -
  RJ559_RS04795 (RJ559_04795) - 1008006..1008827 (+) 822 WP_212784435.1 glycosyltransferase family 25 protein -
  RJ559_RS04800 (RJ559_04800) - 1009039..1009287 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68632.01 Da        Isoelectric Point: 9.7878

>NTDB_id=879917 RJ559_RS04770 WP_310957228.1 1002894..1004678(+) (uvrC) [Helicobacter pylori strain ICDC15003-8-2]
MADLLSSLKNLSNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNPRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKKCLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDV
SHHSSSQCVGGMVVYENNAFQKDSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASDQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=879917 RJ559_RS04770 WP_310957228.1 1002894..1004678(+) (uvrC) [Helicobacter pylori strain ICDC15003-8-2]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAAGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCCGCAATAATGAAATCACGCCTA
ATCCTCGCGCAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTGGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACTAA
AGAAGAGTATTTAAAAATCGCTAAAAAATGTTTAGAAATGATTGAAAATAAAGACAGACTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTAATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTGGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATGGCGCAAGCAATAAGGCGGT
CTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCTGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGATA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCTGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCCCACCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAGGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATGTA
AGCCACCATTCTAGCAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATAACGCATTTCAAAAAGACTCTTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGTTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCTAGCAATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGATCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.98

100

0.98