Detailed information NTG0845274

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: QPE35_RS17510
• Genome accession: NZ_CP127928
• Coordinates: 3193820..3194620 (+)
• Length: 266 a.a.
• NCBI ID: WP_004191960.1
• Uniprot ID: A0AAJ5B1F9
• Organism: Klebsiella pneumoniae strain 2018C07-113
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 3188820..3199620

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QPE35_RS17475 (QPE35_17435)	gspH	3188976..3189491 (+)	516	WP_004177384.1	type II secretion system minor pseudopilin GspH	-
QPE35_RS17480 (QPE35_17440)	gspI	3189488..3189853 (+)	366	WP_002889025.1	type II secretion system minor pseudopilin GspI	-
QPE35_RS17485 (QPE35_17445)	gspJ	3189850..3190446 (+)	597	WP_004145893.1	type II secretion system minor pseudopilin GspJ	-
QPE35_RS17490 (QPE35_17450)	gspK	3190443..3191429 (+)	987	WP_004177385.1	type II secretion system minor pseudopilin GspK	-
QPE35_RS17495 (QPE35_17455)	gspL	3191416..3192609 (+)	1194	WP_025985182.1	type II secretion system protein GspL	-
QPE35_RS17500 (QPE35_17460)	-	3192602..3193087 (+)	486	WP_004145896.1	type II secretion system protein M	-
QPE35_RS17505 (QPE35_17465)	-	3193077..3193823 (+)	747	WP_004145897.1	type II secretion system protein N	-
QPE35_RS17510 (QPE35_17470)	pilD	3193820..3194620 (+)	801	WP_004191960.1	prepilin peptidase	Machinery gene
QPE35_RS17515 (QPE35_17475)	hrpB	3194668..3197097 (-)	2430	WP_004177388.1	ATP-dependent helicase HrpB	-
QPE35_RS17520 (QPE35_17480)	thpR	3197170..3197706 (+)	537	WP_004177389.1	RNA 2',3'-cyclic phosphodiesterase	-
QPE35_RS17525 (QPE35_17485)	sfsA	3197706..3198422 (+)	717	WP_004177390.1	DNA/RNA nuclease SfsA	-
QPE35_RS17530 (QPE35_17490)	dksA	3198585..3199040 (+)	456	WP_002888845.1	RNA polymerase-binding protein DksA	-

Sequence

Protein

• Length: 266 a.a.
• Molecular weight: 29403.04 Da
• Isoelectric Point: 8.8894

>NTDB_id=845274 QPE35_RS17510 WP_004191960.1 3193820..3194620(+) (pilD) [Klebsiella pneumoniae strain 2018C07-113]
MTTLAALSLHFPFVWYGFLLLFGLALGSFYNVVIYRLPRMLTQTADDERITLSTPGSSCPQCRQPIAWRDNIPLLSFLWL
GRRARCCQAPIAWSYPLTELATGLLFILAGALLAPGLPLAGGLVLLSFLLILARIDARTQLLPDRLTLPLLWAGLLFNLN
EVYIALPDAVAGAMAGYLALWSVYWLFRLLTGKEALGYGDFKLLAALGAWCGWQVLPQVLLLASASGLVWTLLQRLWTRQ
SLQQPLAFGPWLALAGGGIFLWQQMI

Nucleotide

• Length: 801 bp

>NTDB_id=845274 QPE35_RS17510 WP_004191960.1 3193820..3194620(+) (pilD) [Klebsiella pneumoniae strain 2018C07-113]
ATGACGACACTAGCCGCGTTATCGCTGCACTTTCCCTTTGTCTGGTATGGCTTTCTACTGCTGTTCGGCCTGGCGCTGGG
CAGCTTTTACAATGTGGTGATCTATCGTCTGCCGCGCATGTTGACCCAGACCGCGGACGACGAGCGGATAACCCTCAGCA
CCCCGGGCTCTTCCTGCCCGCAGTGCCGCCAGCCGATCGCCTGGCGGGACAATATCCCGCTGCTCAGTTTCCTCTGGCTG
GGCCGTCGCGCCCGCTGCTGTCAGGCGCCCATCGCGTGGAGCTATCCGCTGACCGAGCTGGCCACCGGCCTGCTGTTTAT
CCTCGCCGGAGCTTTGCTGGCGCCGGGCCTGCCGCTGGCGGGCGGCCTGGTGCTGCTCTCGTTCCTGCTGATACTGGCGC
GGATTGACGCCCGGACCCAGCTGCTGCCCGATCGCCTGACTCTGCCCCTGCTGTGGGCCGGGCTGCTGTTCAATCTTAAC
GAGGTGTACATTGCCCTGCCGGATGCGGTCGCCGGGGCGATGGCCGGTTATCTGGCGCTGTGGTCGGTCTACTGGCTGTT
CCGCCTGCTGACCGGGAAAGAGGCGCTGGGCTATGGCGATTTTAAGCTGCTGGCGGCGCTGGGCGCCTGGTGCGGCTGGC
AGGTTCTGCCGCAGGTGCTGTTGCTCGCTTCGGCCAGCGGGCTGGTGTGGACCCTACTGCAACGCCTGTGGACCCGGCAG
TCGCTGCAGCAGCCGCTGGCCTTCGGCCCCTGGCTGGCGCTGGCCGGCGGGGGTATTTTTCTCTGGCAGCAGATGATCTA
G

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (21-109)

• Type IV leader peptidase family (Peptidase_A24) (123-231)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio cholerae strain A1552	49.057	99.624	0.489
pilD	Vibrio campbellii strain DS40M4	46.545	100	0.481
pilD	Acinetobacter nosocomialis M2	46.388	98.872	0.459
pilD	Acinetobacter baumannii D1279779	45.627	98.872	0.451
pilD	Neisseria gonorrhoeae MS11	43.922	95.865	0.421