Detailed information NTG0803480

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: P3U51_RS09635
• Genome accession: NZ_CP120134
• Coordinates: 1950143..1951186 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain Dog043
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1945143..1956186

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P3U51_RS09605 (P3U51_09605)	-	1945565..1946821 (-)	1257	WP_001789555.1	aminopeptidase	-
P3U51_RS09610 (P3U51_09610)	-	1946824..1947024 (-)	201	WP_000180460.1	DUF1128 family protein	-
P3U51_RS09615 (P3U51_09615)	-	1947171..1947635 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
P3U51_RS09620 (P3U51_09620)	-	1947642..1947917 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
P3U51_RS09625 (P3U51_09625)	-	1948195..1949412 (+)	1218	WP_000037078.1	YihY/virulence factor BrkB family protein	-
P3U51_RS09630 (P3U51_09630)	vraR	1949524..1950153 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
P3U51_RS09635 (P3U51_09635)	vraS	1950143..1951186 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
P3U51_RS09640 (P3U51_09640)	liaF	1951183..1951884 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
P3U51_RS09645 (P3U51_09645)	-	1951899..1952285 (-)	387	WP_001110179.1	hypothetical protein	-
P3U51_RS09650 (P3U51_09650)	map	1952502..1953260 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
P3U51_RS09655 (P3U51_09655)	-	1953731..1954717 (+)	987	WP_043044165.1	FUSC family protein	-
P3U51_RS09660 (P3U51_09660)	-	1955149..1955562 (-)	414	WP_001566709.1	hypothetical protein	-
P3U51_RS09665 (P3U51_09665)	-	1955591..1955701 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=803480 P3U51_RS09635 WP_001017131.1 1950143..1951186(-) (vraS) [Staphylococcus aureus strain Dog043]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=803480 P3U51_RS09635 WP_001017131.1 1950143..1951186(-) (vraS) [Staphylococcus aureus strain Dog043]
ATGAACCACTATATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1