Detailed information NTG0802831

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: P3U52_RS09345
• Genome accession: NZ_CP120090
• Coordinates: 1909789..1910832 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain Dog112
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1904789..1915832

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P3U52_RS09315 (P3U52_09315)	-	1905211..1906467 (-)	1257	WP_001789555.1	aminopeptidase	-
P3U52_RS09320 (P3U52_09320)	-	1906470..1906670 (-)	201	WP_000180460.1	DUF1128 family protein	-
P3U52_RS09325 (P3U52_09325)	-	1906817..1907281 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
P3U52_RS09330 (P3U52_09330)	-	1907288..1907563 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
P3U52_RS09335 (P3U52_09335)	-	1907841..1909058 (+)	1218	WP_000037078.1	YihY/virulence factor BrkB family protein	-
P3U52_RS09340 (P3U52_09340)	vraR	1909170..1909799 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
P3U52_RS09345 (P3U52_09345)	vraS	1909789..1910832 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
P3U52_RS09350 (P3U52_09350)	liaF	1910829..1911530 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
P3U52_RS09355 (P3U52_09355)	-	1911545..1911931 (-)	387	WP_001110179.1	hypothetical protein	-
P3U52_RS09360 (P3U52_09360)	map	1912148..1912906 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
P3U52_RS09365 (P3U52_09365)	-	1913377..1914363 (+)	987	WP_043044165.1	FUSC family protein	-
P3U52_RS09370 (P3U52_09370)	-	1914736..1915149 (-)	414	WP_001566709.1	hypothetical protein	-
P3U52_RS09375 (P3U52_09375)	-	1915178..1915288 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=802831 P3U52_RS09345 WP_001017131.1 1909789..1910832(-) (vraS) [Staphylococcus aureus strain Dog112]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=802831 P3U52_RS09345 WP_001017131.1 1909789..1910832(-) (vraS) [Staphylococcus aureus strain Dog112]
ATGAACCACTATATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1