Detailed information NTG0783035

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: PQQ27_RS13115
• Genome accession: NZ_CP117238
• Coordinates: 2618213..2619100 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain ATCC 23235
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2613213..2624100

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PQQ27_RS13085 (PQQ27_13085)	-	2613232..2613324 (+)	93	WP_010956583.1	hypothetical protein	-
PQQ27_RS13090 (PQQ27_13090)	-	2613432..2613929 (-)	498	WP_001065268.1	glutathione peroxidase	-
PQQ27_RS13095 (PQQ27_13095)	-	2613939..2614199 (-)	261	WP_001791974.1	hypothetical protein	-
PQQ27_RS13100 (PQQ27_13100)	-	2614581..2614694 (-)	114	Protein_2508	hypothetical protein	-
PQQ27_RS13105 (PQQ27_13105)	-	2615353..2617353 (-)	2001	WP_000776749.1	ABC transporter permease	-
PQQ27_RS13110 (PQQ27_13110)	-	2617350..2618105 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
PQQ27_RS13115 (PQQ27_13115)	braS	2618213..2619100 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
PQQ27_RS13120 (PQQ27_13120)	braR	2619111..2619776 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
PQQ27_RS13125 (PQQ27_13125)	-	2619802..2620002 (-)	201	WP_000604730.1	hypothetical protein	-
PQQ27_RS13130 (PQQ27_13130)	-	2620200..2621624 (+)	1425	WP_000953755.1	alkaline phosphatase	-
PQQ27_RS13135 (PQQ27_13135)	-	2621694..2621804 (+)	111	Protein_2515	hypothetical protein	-
PQQ27_RS13140 (PQQ27_13140)	-	2621907..2622362 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
PQQ27_RS13145 (PQQ27_13145)	-	2622607..2623368 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=783035 PQQ27_RS13115 WP_000143425.1 2618213..2619100(-) (braS) [Staphylococcus aureus strain ATCC 23235]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=783035 PQQ27_RS13115 WP_000143425.1 2618213..2619100(-) (braS) [Staphylococcus aureus strain ATCC 23235]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1