Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   NY40_RS03265 Genome accession   NZ_AP014523
Coordinates   643474..644211 (+) Length   245 a.a.
NCBI ID   WP_021177589.1    Uniprot ID   A0A060Q0J2
Organism   Helicobacter pylori NY40     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 638474..649211
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NY40_RS03240 (NY40_0649) panD 640632..640985 (+) 354 WP_041050389.1 aspartate 1-decarboxylase -
  NY40_RS03245 (NY40_0650) - 640988..641281 (+) 294 WP_000347917.1 YbaB/EbfC family nucleoid-associated protein -
  NY40_RS03250 (NY40_0651) - 641281..642285 (+) 1005 WP_041050391.1 PDZ domain-containing protein -
  NY40_RS03255 (NY40_0652) comB6 642293..643348 (+) 1056 WP_041050393.1 P-type conjugative transfer protein TrbL Machinery gene
  NY40_RS03260 comB7 643364..643477 (+) 114 WP_001217873.1 hypothetical protein Machinery gene
  NY40_RS03265 (NY40_0653) comB8 643474..644211 (+) 738 WP_021177589.1 type IV secretion system protein Machinery gene
  NY40_RS03270 (NY40_0654) comB9 644211..645194 (+) 984 WP_041050396.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  NY40_RS03275 (NY40_0655) comB10 645187..646317 (+) 1131 WP_021177591.1 DNA type IV secretion system protein ComB10 Machinery gene
  NY40_RS03280 (NY40_0656) - 646387..647805 (+) 1419 WP_041050398.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  NY40_RS03285 (NY40_0657) gmd 647815..648960 (+) 1146 WP_041050400.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28526.74 Da        Isoelectric Point: 8.9546

>NTDB_id=65786 NY40_RS03265 WP_021177589.1 643474..644211(+) (comB8) [Helicobacter pylori NY40]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISILPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLLNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
TNRGD

Nucleotide


Download         Length: 738 bp        

>NTDB_id=65786 NY40_RS03265 WP_021177589.1 643474..644211(+) (comB8) [Helicobacter pylori NY40]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAGTTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAACGATTTGGACATGCAAAGCGTGTTTCGGTTGGAAAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTTTTAATCAGCATTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAATCGCATTGACGATAAATCGCGCT
ATGAACTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACGCAAAACAGCATTTAT
GCGCAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
TTCCATTGCGGCTAAACTTTTGAATGAAAACAAGCTCGTGTATGAAAAGCGTTATAAGATCGTATTGAGCTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
ACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A060Q0J2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.166

100

0.98

Multiple sequence alignment