Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   FOC74_RS12035 Genome accession   NZ_CP053997
Coordinates   1971735..1972418 (-) Length   227 a.a.
NCBI ID   WP_000350720.1    Uniprot ID   A0A0J1I2I3
Organism   Bacillus cereus strain FDAARGOS_780     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1966735..1977418
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC74_RS12020 (FOC74_12020) pepF 1966915..1968741 (-) 1827 WP_000003393.1 oligoendopeptidase F Regulator
  FOC74_RS12025 (FOC74_12025) - 1968792..1970036 (-) 1245 WP_000612273.1 competence protein CoiA -
  FOC74_RS12030 (FOC74_12030) - 1970118..1971662 (-) 1545 WP_000799201.1 cardiolipin synthase -
  FOC74_RS12035 (FOC74_12035) mecA 1971735..1972418 (-) 684 WP_000350720.1 adaptor protein MecA Regulator
  FOC74_RS12040 (FOC74_12040) - 1972745..1973419 (+) 675 WP_000362609.1 TerC family protein -
  FOC74_RS12045 (FOC74_12045) spx 1973469..1973864 (-) 396 WP_000258267.1 transcriptional regulator Spx -
  FOC74_RS12050 (FOC74_12050) - 1974457..1974660 (+) 204 WP_000559980.1 hypothetical protein -
  FOC74_RS12055 (FOC74_12055) - 1974687..1976333 (-) 1647 WP_000727260.1 peptide ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26994.06 Da        Isoelectric Point: 3.9822

>NTDB_id=449874 FOC74_RS12035 WP_000350720.1 1971735..1972418(-) (mecA) [Bacillus cereus strain FDAARGOS_780]
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAEL
SKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQVGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELY
SFEDRYYVYVEFDEVLHDEEEIDRILSIVLEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT

Nucleotide


Download         Length: 684 bp        

>NTDB_id=449874 FOC74_RS12035 WP_000350720.1 1971735..1972418(-) (mecA) [Bacillus cereus strain FDAARGOS_780]
TTGGATATTGAAAGAATTAATGATCATACGATGAAGTTTTTTATTACGTACATTGATATAGAGGACAGAGGCTTTAATCG
TGAGGAAATTTGGTATGACCGCGAAAGAAGCGAAGAGCTCTTTTGGGAAATGATGGACGAAGCTCGTGATCATGACGATT
TCTTTATTGATGGGCCGTTATGGATTCAAGTGCAAGCAGTCGATAAAGGGATTGAAGTACTTGTAACGAAAGCAGAACTT
TCAAAGGATGGACAAAAGCTAGAACTACCAATAGGTGTAGATAAAATTATAGACATTCCTCTAGATGAAGGCATTGAATC
ATTATTCCAGCAAGAATTAGTGGAAGAGGTAGAAGAACAAGTAGGAACAAACTTTAACGAAGATGGTACGTTTGGCTTTT
TAATTAAGTTTAATGATTTTGAAGATGTCATTTCATTAAGTCATCGTCTTATCTTTGAAGATATAAAAGATGAGCTGTAT
TCATTTGAGGACCGCTATTATGTATATGTGGAATTCGATGAAGTGCTACATGATGAGGAAGAAATTGATCGCATTTTAAG
TATTGTTTTAGAATACGGAGAAGAATCAACTTTAACAATTCATCGTGTAAGTGAGTATGGGAAACAAATTGTGAAAGAGC
ATGCGCTTGAAACAATTCGCAATAATTTTCCTGCTAAAACGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0J1I2I3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

55.702

100

0.559