Detailed information NTG1003560

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXQ87_RS09225
• Genome accession: NZ_CP156986
• Coordinates: 1896037..1897080 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN68
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1891037..1902080

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ87_RS09195 (UXQ87_09195)	-	1891459..1892715 (-)	1257	WP_001789555.1	aminopeptidase	-
UXQ87_RS09200 (UXQ87_09200)	-	1892718..1892918 (-)	201	WP_000180460.1	DUF1128 family protein	-
UXQ87_RS09205 (UXQ87_09205)	-	1893065..1893529 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXQ87_RS09210 (UXQ87_09210)	-	1893536..1893811 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXQ87_RS09215 (UXQ87_09215)	-	1894089..1895306 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
UXQ87_RS09220 (UXQ87_09220)	vraR	1895418..1896047 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
UXQ87_RS09225 (UXQ87_09225)	vraS	1896037..1897080 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXQ87_RS09230 (UXQ87_09230)	liaF	1897077..1897778 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXQ87_RS09235 (UXQ87_09235)	-	1897793..1898179 (-)	387	WP_001110179.1	hypothetical protein	-
UXQ87_RS09240 (UXQ87_09240)	map	1898396..1899154 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXQ87_RS09245 (UXQ87_09245)	-	1899626..1900612 (+)	987	WP_000999714.1	aromatic acid exporter family protein	-
UXQ87_RS09250 (UXQ87_09250)	-	1901043..1901456 (-)	414	WP_025173836.1	hypothetical protein	-
UXQ87_RS09255 (UXQ87_09255)	-	1901485..1901595 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1003560 UXQ87_RS09225 WP_001017131.1 1896037..1897080(-) (vraS) [Staphylococcus aureus strain BSN68]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1003560 UXQ87_RS09225 WP_001017131.1 1896037..1897080(-) (vraS) [Staphylococcus aureus strain BSN68]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1