| # | Name | Organism | Replicon | Location | Function |
| 1 | Ydd | Bacillus atrophaeus 1942 | chromosome [NC_014639] | 1272..16289 | conjugation |
| 2 | Ydd | Bacillus pumilus SAFR-032 | chromosome [NC_009848] | 593151..615368 | NA |
| 3 | Ydd  | Bacillus subtilis subsp. subtilis str. 168 | chromosome [NC_000964] | 533338..545011 | conjugation |
| 4 | Tra_Tn | Clostridiales genomosp. BVAB3 str. UPII9-5 | chromosome [NC_013895] | 539356..550020 | conjugation |
| 5 | Tra_Tn | Clostridium difficile 630 | chromosome [NC_009089] | 3897502..3909543 | conjugation |
| 6 | Tra_Tn | Clostridium difficile 630 | chromosome [NC_009089] | 3950845..3963219 | conjugation |
| 7 | Tra_Tn | Clostridium difficile 630 | chromosome [NC_009089] | 440599..452591 | conjugation |
| 8 | Tra_Tn | Clostridium difficile 630 | chromosome [NC_009089] | 586451..599749 | conjugation |
| 9 | Tra_Tn | Clostridium difficile CD196 | chromosome [NC_013315] | 4024620..4037007 | NA |
| 10 | Tra_Tn | Clostridium difficile R20291 | chromosome [NC_013316] | 4105406..4117793 | NA |
| 11 | Tcp | Clostridium perfringens CPE str. F4969 plasmid pCPF4969 (NC_007772) | plasmid pCPF4969 [NC_007772] | 12791..26569 | conjugation |
| 12 | Tcp | Clostridium perfringens plasmid pCP8533etx (NC_011412) | plasmid pCP8533etx [NC_011412] | 3332..13841 | conjugation |
| 13 | Tcp | Clostridium perfringens plasmid pCPF5603 (NC_007773) | plasmid pCPF5603 [NC_007773] | 65789..75268 | conjugation |
| 14 | Tcp | Clostridium perfringens plasmid pCPPB-1 (NC_015712) | plasmid pCPPB-1 [NC_015712] | 33834..43434 | conjugation |
| 15 | Tcp | Clostridium perfringens plasmid pCW3 (NC_010937) | plasmid pCW3 [NC_010937] | 25890..36479 | conjugation |
| 16 | Tra_p | Enterococcus faecalis plasmid pAMbeta1 (NC_013514) | plasmid pAMbeta1 [NC_013514] | 15049..27714 | NA |
| 17 | Prg/Pcf | Enterococcus faecalis plasmid pBEE99 (NC_013533) | plasmid pBEE99 [NC_013533] | 8127..34867 | conjugation |
| 18 | Prg/Pcf | Enterococcus faecalis plasmid pCF10 (NC_006827) | plasmid pCF10 [NC_006827] | 10015..35356 | conjugation |
| 19 | Tra_p | Enterococcus faecalis plasmid pRE25 (NC_008445) | plasmid pRE25 [NC_008445] | 21625..34233 | conjugation |
| 20 | Tra_p | Enterococcus faecalis plasmid pWZ1668 (NC_014475) | plasmid pWZ1668 [NC_014475] | 1495..2208; 38046..48365 | conjugation |
| 21 | Tra_Tn | Enterococcus faecalis V583 | chromosome [NC_004668] | 1819850..1837475 | NA |
| 22 | Prg/Pcf | Enterococcus faecalis V583 | plasmid pTEF2 [NC_004671] | 7092..32433 | conjugation |
| 23 | Tra_Tn | Enterococcus faecalis V583 | chromosome [NC_004668] | 2197119..2203989; 2259509..2265535 | NA |
| 24 | Ydd | Leuconostoc citreum KM20 | plasmid pLCK1 [NC_010470] | 18656..30648 | NA |
| 25 | Tra_Tn | Listeria monocytogenes EGD-e | chromosome [NC_003210] | 1137997..1149003 | conjugation |
| 26 | Ydd | Listeria welshimeri serovar 6b str. SLCC5334 | chromosome [NC_008555] | 798509..813382 | NA |
| 27 | Ydd | Staphylococcus aureus subsp. aureus COL | chromosome [NC_002951] | 1611280..1618789 | conjugation |
| 28 | Ydd | Staphylococcus aureus subsp. aureus ED98 | chromosome [NC_013450] | 56212..65323 | NA |
| 29 | Ydd | Staphylococcus aureus subsp. aureus ED98 | chromosome [NC_013450] | 1967115..1974624 | conjugation |
| 30 | Ydd | Staphylococcus aureus subsp. aureus ED98 | chromosome [NC_013450] | 1749551..1758353 | NA |
| 31 | Ydd | Staphylococcus aureus subsp. aureus MRSA252 | chromosome [NC_002952] | 1354503..1362012 | conjugation |
| 32 | Tra_Tn | Staphylococcus aureus subsp. aureus Mu3 | chromosome [NC_009782] | 442164..454407 | conjugation |
| 33 | Tra_Tn | Staphylococcus aureus subsp. aureus Mu50 | chromosome [NC_002758] | 442161..454403 | conjugation |
| 34 | Ydd | Staphylococcus aureus subsp. aureus USA300_FPR3757 | chromosome [NC_007793] | 1634116..1641625 | conjugation |
| 35 | Ydd | Staphylococcus aureus subsp. aureus USA300_TCH1516 | chromosome [NC_010079] | 684312..691821 | conjugation |
| 36 | Tra_Tn | Staphylococcus pseudintermedius HKU10-03 | chromosome [NC_014925] | 2201927..2212592 | conjugation |
| 37 | Tra_Tn | Streptococcus agalactiae 2603V/R | chromosome [NC_004116] | 929751..940415 | conjugation |
| 38 | Prg/Pcf | Streptococcus agalactiae NEM316 | chromosome [NC_004368] | 1173758..1193432 | conjugation |
| 39 | Ydd | Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069 | chromosome [NC_015215] | 2270610..2282564 | NA |
| 40 | Tra_Tn | Streptococcus gallolyticus UCN34 | chromosome [NC_013798] | 1774651..1785316 | conjugation |
| 41 | Ydd | Streptococcus gallolyticus UCN34 | chromosome [NC_013798] | 1744118..1758740 | NA |
| 42 | Tra_Tn | Streptococcus mitis B6 | chromosome [NC_013853] | 1326172..1338415 | conjugation |
| 43 | Ydd | Streptococcus mutans UA159 | chromosome [NC_004350] | 195072..206423 | conjugation |
| 44 | Tra_Tn | Streptococcus oralis Uo5 | chromosome [NC_015291] | 1825801..1836253 | conjugation |
| 45 | Tra_Tn | Streptococcus pasteurianus ATCC 43144 | chromosome [NC_015600] | 1725064..1735417 | NA |
| 46 | Tra_Tn | Streptococcus pneumoniae 670-6B | chromosome [NC_014498] | 1076620..1090136 | conjugation |
| 47 | Tra_Tn | Streptococcus pneumoniae ATCC 700669 | chromosome [NC_011900] | 1262026..1278225 | conjugation |
| 48 | Tra_Tn | Streptococcus pneumoniae CGSP14 | chromosome [NC_010582] | 160675..171343 | conjugation |
| 49 | Tra_Tn | Streptococcus pneumoniae G54 | chromosome [NC_011072] | 1194713..1208215 | NA |
| 50 | Tra_Tn | Streptococcus pneumoniae Hungary19A-6 | chromosome [NC_010380] | 1308321..1321838 | conjugation |
| 51 | Tra_Tn | Streptococcus pneumoniae P1031 | chromosome [NC_012467] | 1074867..1089607 | conjugation |
| 52 | Tra_Tn | Streptococcus pneumoniae Taiwan19F-14 | chromosome [NC_012469] | 1786241..1796906 | conjugation |
| 53 | Tra_Tn | Streptococcus pneumoniae TCH8431/19A | chromosome [NC_014251] | 2006079..2019593 | conjugation |
| 54 | Tra_Tn | Streptococcus pseudopneumoniae IS7493 | chromosome [NC_015875] | 225433..236101 | NA |
| 55 | Tra_p | Streptococcus pyogenes plasmid pSM19035 (NC_006979) | plasmid pSM19035 [NC_006979] | 17808..28618 | NA |
| 56 | Tra_Tn | Streptococcus suis 05ZYH33 | chromosome [NC_009442] | 894536..905201 | effector translocation and conjugation |
| 57 | Tra_Tn | Streptococcus suis 98HAH33 | chromosome [NC_009443] | 894243..904908 | conjugation |
| 58 | Tra_Tn | Streptococcus suis BM407 | chromosome [NC_012926] | 1051080..1063814 | conjugation |
| 59 | Tra_Tn | Streptococcus suis BM407 | chromosome [NC_012926] | 541683..552348 | conjugation |
| 60 | Tra_Tn | Streptococcus suis SC84 | chromosome [NC_012924] | 894280..904945 | conjugation |
| T4SS derived from experimental literature | |||||