Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   ELZ52_RS03770 Genome accession   NZ_LR134085
Coordinates   732309..732983 (+) Length   224 a.a.
NCBI ID   WP_001166505.1    Uniprot ID   Q2FIY0
Organism   Staphylococcus aureus strain NCTC12233     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 727309..737983
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ52_RS03740 (NCTC12233_00695) - 727524..728591 (+) 1068 WP_000980137.1 membrane protein -
  ELZ52_RS03745 (NCTC12233_00696) - 728742..729785 (+) 1044 WP_001030771.1 alpha/beta hydrolase -
  ELZ52_RS03755 (NCTC12233_00697) - 730114..730542 (+) 429 WP_000198504.1 hypothetical protein -
  ELZ52_RS03760 (NCTC12233_00698) - 730751..731257 (-) 507 WP_000940134.1 GNAT family N-acetyltransferase -
  ELZ52_RS03765 (NCTC12233_00699) graX 731370..732293 (+) 924 WP_000802946.1 auxiliary protein GraX/ApsX -
  ELZ52_RS03770 (NCTC12233_00700) braR 732309..732983 (+) 675 WP_001166505.1 response regulator transcription factor GraR/ApsR Regulator
  ELZ52_RS03775 (NCTC12233_00701) graS 732976..734016 (+) 1041 WP_001061252.1 histidine kinase GraS/ApsS -
  ELZ52_RS03780 (NCTC12233_00702) vraF 734160..734921 (+) 762 WP_000985996.1 ABC transporter ATP-binding protein VraF -
  ELZ52_RS03785 (NCTC12233_00703) vraG 734911..736800 (+) 1890 WP_000143623.1 ABC transporter permease VraG -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 26078.92 Da        Isoelectric Point: 4.3968

>NTDB_id=997093 ELZ52_RS03770 WP_001166505.1 732309..732983(+) (braR) [Staphylococcus aureus strain NCTC12233]
MQILLVEDDNTLFQELKKELEQWDFNVAGIEDFGKVMDTFESFNPEIVILDVQLPKYDGFYWCRKMREVSNVPILFLSSR
DNPMDQVMSMELGADDYMQKPFYTNVLIAKLQAIYRRVYEFTAEEKRTLTWQDAVVDLSKDSIQKGDQTIFLSKTEMIIL
EILITKKNQIVSRDTIITALWDDEAFVSDNTLTVNVNRLRKKLSEISMDSAIETKVGKGYMAHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=997093 ELZ52_RS03770 WP_001166505.1 732309..732983(+) (braR) [Staphylococcus aureus strain NCTC12233]
ATGCAAATACTACTAGTAGAAGATGACAATACTTTGTTTCAAGAATTGAAAAAAGAATTAGAACAATGGGATTTTAATGT
TGCTGGTATTGAAGATTTCGGCAAAGTAATGGATACATTTGAAAGTTTTAATCCTGAAATTGTTATATTGGATGTTCAAT
TACCTAAATATGATGGGTTTTATTGGTGCAGAAAAATGAGAGAAGTTTCCAACGTACCAATATTATTTTTATCATCTCGT
GATAATCCAATGGATCAAGTGATGAGTATGGAACTTGGCGCAGATGATTATATGCAAAAACCGTTCTATACCAATGTATT
AATTGCTAAATTACAAGCGATTTATCGTCGTGTCTATGAGTTTACAGCTGAAGAAAAACGTACATTGACTTGGCAAGATG
CTGTCGTTGATCTATCAAAAGATAGTATACAAAAAGGTGATCAGACGATTTTCCTGTCCAAAACAGAAATGATTATATTA
GAAATTCTTATTACCAAAAAAAATCAAATCGTTTCGAGAGATACAATTATCACTGCATTATGGGATGATGAAGCATTTGT
TAGTGATAATACGTTAACAGTAAATGTGAATCGTTTACGAAAAAAATTATCTGAAATTAGTATGGATAGTGCAATCGAAA
CAAAAGTAGGAAAAGGATATATGGCTCATGAATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(148-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2FIY0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

40.909

98.214

0.402

Multiple sequence alignment