Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   ABC810_RS01635 Genome accession   NZ_CP155532
Coordinates   318113..318733 (+) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain SP264     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 313113..323733
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC810_RS01615 (ABC810_01615) pneA2 315983..316171 (-) 189 WP_000786759.1 two-peptide bacteriocin subunit PneA2 -
  ABC810_RS01620 (ABC810_01620) pneA1 316178..316402 (-) 225 WP_000181087.1 two-peptide bacteriocin subunit PneA1 -
  ABC810_RS01625 (ABC810_01625) - 316505..316675 (-) 171 WP_001227862.1 PhrA family quorum-sensing system peptide -
  ABC810_RS01630 (ABC810_01630) - 316867..317730 (+) 864 WP_001093641.1 helix-turn-helix transcriptional regulator -
  ABC810_RS01635 (ABC810_01635) comM 318113..318733 (+) 621 WP_000839908.1 hypothetical protein Regulator
  ABC810_RS01640 (ABC810_01640) tsaE 318819..319262 (+) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  ABC810_RS01645 (ABC810_01645) - 319252..319770 (+) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  ABC810_RS01650 (ABC810_01650) - 319778..320794 (+) 1017 WP_000239284.1 LCP family protein -
  ABC810_RS01655 (ABC810_01655) cinA 320879..322135 (+) 1257 WP_000642705.1 competence/damage-inducible protein A Machinery gene
  ABC810_RS01660 (ABC810_01660) recA 322190..323356 (+) 1167 WP_001085462.1 recombinase RecA Machinery gene

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=997091 ABC810_RS01635 WP_000839908.1 318113..318733(+) (comM) [Streptococcus pneumoniae strain SP264]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=997091 ABC810_RS01635 WP_000839908.1 318113..318733(+) (comM) [Streptococcus pneumoniae strain SP264]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTGGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369

Multiple sequence alignment