Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   EGX68_RS06840 Genome accession   NZ_CP033735
Coordinates   1333680..1333826 (-) Length   48 a.a.
NCBI ID   WP_230620687.1    Uniprot ID   -
Organism   Staphylococcus cohnii strain FDAARGOS_538     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1328680..1338826
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX68_RS06820 (EGX68_06830) rpsT 1329375..1329626 (+) 252 WP_019469386.1 30S ribosomal protein S20 -
  EGX68_RS06825 (EGX68_06835) holA 1329858..1330832 (-) 975 WP_019469387.1 DNA polymerase III subunit delta -
  EGX68_RS13760 - 1330908..1331753 (-) 846 WP_019469388.1 ComEC/Rec2 family competence protein -
  EGX68_RS13950 - 1331838..1332038 (-) 201 Protein_1324 ComEC/Rec2 family competence protein -
  EGX68_RS13955 - 1332133..1333041 (-) 909 WP_258026228.1 ComEC/Rec2 family competence protein -
  EGX68_RS06835 (EGX68_06845) - 1333137..1333598 (-) 462 WP_019469390.1 ComE operon protein 2 -
  EGX68_RS06840 (EGX68_06850) comEA 1333680..1333826 (-) 147 WP_230620687.1 helix-hairpin-helix domain-containing protein Machinery gene
  EGX68_RS06845 (EGX68_06855) - 1333862..1334413 (-) 552 WP_103211239.1 hypothetical protein -
  EGX68_RS06850 (EGX68_06860) - 1334463..1335188 (-) 726 WP_040030029.1 class I SAM-dependent methyltransferase -
  EGX68_RS06855 (EGX68_06865) rsfS 1335191..1335544 (-) 354 WP_103211240.1 ribosome silencing factor -
  EGX68_RS06860 (EGX68_06870) yqeK 1335545..1336129 (-) 585 WP_040030028.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  EGX68_RS06865 (EGX68_06875) nadD 1336119..1336691 (-) 573 WP_026034801.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  EGX68_RS06870 (EGX68_06880) yhbY 1336691..1336981 (-) 291 WP_019469395.1 ribosome assembly RNA-binding protein YhbY -
  EGX68_RS06875 (EGX68_06885) aroE 1336994..1337791 (-) 798 WP_019469396.1 shikimate dehydrogenase -

Sequence

Protein


Download         Length: 48 a.a.        Molecular weight: 5377.24 Da        Isoelectric Point: 10.2107

>NTDB_id=325187 EGX68_RS06840 WP_230620687.1 1333680..1333826(-) (comEA) [Staphylococcus cohnii strain FDAARGOS_538]
MPGIGKVKTKAIIEYREQNGNFKSIDQLKEINGFGTKTIEKLSSHLTI

Nucleotide


Download         Length: 147 bp        

>NTDB_id=325187 EGX68_RS06840 WP_230620687.1 1333680..1333826(-) (comEA) [Staphylococcus cohnii strain FDAARGOS_538]
ATGCCTGGAATAGGAAAGGTTAAAACTAAAGCTATCATTGAATATCGTGAGCAAAACGGTAATTTTAAATCTATTGATCA
ATTGAAAGAAATTAATGGATTCGGTACTAAAACAATAGAAAAATTAAGTTCACATTTAACAATCTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(2-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

54.167

100

0.542
  comEA Staphylococcus aureus N315

54.167

100

0.542
  Cj0011c Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

50

100

0.5
  comE Neisseria gonorrhoeae MS11

47.917

100

0.479
  comE Neisseria gonorrhoeae MS11

47.917

100

0.479
  comE Neisseria gonorrhoeae MS11

47.917

100

0.479
  comEA Lactococcus lactis subsp. cremoris KW2

47.917

100

0.479
  comE Neisseria gonorrhoeae MS11

47.917

100

0.479
  comEA/celA/cilE Streptococcus pneumoniae R6

50

95.833

0.479
  comEA/celA/cilE Streptococcus pneumoniae Rx1

50

95.833

0.479
  comEA/celA/cilE Streptococcus mitis NCTC 12261

50

95.833

0.479
  comEA/celA/cilE Streptococcus mitis SK321

50

95.833

0.479
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

50

95.833

0.479
  comEA/celA/cilE Streptococcus pneumoniae D39

50

95.833

0.479
  comEA Acinetobacter baumannii D1279779

45.833

100

0.458
  comEA Acinetobacter baylyi ADP1

45.833

100

0.458
  comEA/comE1 Glaesserella parasuis strain SC1401

51.22

85.417

0.438
  comEA Acinetobacter baumannii strain A118

43.75

100

0.438
  comEA Bacillus subtilis subsp. subtilis str. 168

41.667

100

0.417
  comEA Latilactobacillus sakei subsp. sakei 23K

43.478

95.833

0.417
  comE1/comEA Haemophilus influenzae Rd KW20

48.78

85.417

0.417
  comEA Streptococcus thermophilus LMD-9

39.583

100

0.396
  comEA Vibrio cholerae C6706

48.649

77.083

0.375
  comEA Vibrio cholerae strain A1552

48.649

77.083

0.375
  comA Synechocystis sp. PCC 6803

38.298

97.917

0.375
  comEA Legionella pneumophila str. Paris

46.154

81.25

0.375
  comEA Legionella pneumophila strain ERS1305867

46.154

81.25

0.375

Multiple sequence alignment