TAfinder detailed results

Overview

Job ID 9mizKMmBqU
Sequence name Escherichia coli strain DH5alpha chromosome, complete genome.
Predicted type II

Toxin (Protein)


Predicted family chpB (T1049) Predicted domain PRK09812
Locus tag C1467_RS22090 Length 116 a.a.
Coordinates 4269419..4269769 (-)

Antitoxin (Protein)


Predicted family chpS (AT1049) Predicted domain PRK11347 (ChpS)
Locus tag C1467_RS22095 Length 83 a.a.
Coordinates 4269763..4270014 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1467_RS22070 4264865..4265887 - 1023 WP_001296689.1 ABC transporter permease -
C1467_RS22075 4265901..4267403 - 1503 WP_000205800.1 sugar ABC transporter ATP-binding protein -
C1467_RS22080 4267543..4268499 - 957 WP_000265933.1 galactofuranose ABC transporter substrate-binding protein YtfQ -
C1467_RS22085 4268809..4269339 + 531 WP_000055072.1 inorganic diphosphatase -
C1467_RS22090 4269419..4269769 - 351 WP_000239579.1 endoribonuclease toxin ChpB Toxin
C1467_RS22095 4269763..4270014 - 252 WP_001223208.1 type II toxin-antitoxin system antitoxin ChpS Antitoxin
C1467_RS22100 4270227..4270568 - 342 WP_001219160.1 gamma-glutamylcyclotransferase -
C1467_RS22105 4270571..4274350 - 3780 WP_000060921.1 autotransporter assembly complex protein TamB -

Domains

The domains were predicted by HMMER and were sorted by score.

Toxin

PRK09812 (E-value: 1e-62, Score:207.5)

(1-116)

PRK09907 (E-value: 4.7e-18, Score:63.2)

(7-109)

COG2337 (MazF) (E-value: 2.6e-14, Score:51.4)

(9-112)

PF02452 (PemK) (E-value: 1.7e-09, Score:36.1)

(2-104)

Antitoxin

PRK11347 (ChpS) (E-value: 3.1e-59, Score:195.2)

(1-83)

COG2336 (MazE) (E-value: 1.5e-33, Score:113.3)

(2-82)

PRK09798 (MazE) (E-value: 5.1e-09, Score:34.4)

(5-82)

smart00966 (AbrB) (E-value: 1.5e-07, Score:29.5)

(8-76)

TIGR02609 (doc) (E-value: 3e-06, Score:25.3)

(4-51)

TIGR01439 (AbrB) (E-value: 0.0027, Score:15.5)

(13-58)

COG2002 (AbrB) (E-value: 0.0063, Score:14.2)

(19-75)

COG4456 (VagC) (E-value: 0.017, Score:13.2)

(21-56)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 12511.45 Da        Isoelectric Point: 5.6219

>WP_000239579.1 TA_33 Toxin
MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLGMTLVAPITQGGNFARY
AGFSVPLHCEEGDVHGVVLVNQVRMMDLRARLAKRIGLAADEVVEEALLRLQAVVE*

Download         Length: 351 bp

>WP_000239579.1 TA_33 Toxin
TTATTCCACCACCGCCTGCAAGCGTAATAACGCCTCTTCCACCACCTCATCCGCAGCCAG
ACCAATACGCTTTGCCAGCCGGGCGCGTAGATCCATCATCCGCACCTGATTCACCAGCAC
CACGCCGTGCACATCGCCTTCTTCGCAATGTAAAGGAACGCTAAATCCGGCATAACGGGC
AAAATTTCCGCCCTGCGTAATGGGGGCCACCAGCGTCATTCCCAGTTGATTAAAGGCTTG
AACGGAGAGCACAAGCGCAGGTCGACCAGCACCTTGCTGTTCATGGCCGCTTGCTGGATC
AAAGCCAACCAGCACAATGTCTCCCCGTTCAAATTCACTTTTCTTTACCAT

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9271.58 Da        Isoelectric Point: 4.4201

>WP_001223208.1 TA_33 Antitoxin
MRITIKRWGNSAGMVIPNIVMKELNLQPGQSVEAQVSNNQLILTPISRRYSLDELLAQCD
MNAAELSEQDVWGKSTPAGDEIW*

Download         Length: 252 bp

>WP_001223208.1 TA_33 Antitoxin
TTACCATATTTCGTCACCCGCAGGGGTGGATTTACCCCAGACATCCTGCTCGCTAAGTTC
CGCGGCGTTCATGTCACACTGTGCCAGCAGTTCATCAAGCGAGTAGCGCCTGGAGATGGG
TGTCAGAATCAGTTGGTTGTTGCTCACCTGCGCTTCCACGCTCTGCCCCGGCTGTAAGTT
AAGTTCTTTCATTACGATATTGGGAATGACCATACCTGCACTGTTCCCCCATCTTTTTAT
GGTAATACGCAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
T1049 Escherichia coli str. K-12 substr. MG1655

99.138

100

0.983
T1076 Shigella flexneri 2b

43.86

85.714

0.427
T10069 Klebsiella pneumoniae subsp. pneumoniae MGH 78578

37.615

97.321

0.35
T10067 Agrobacterium tumefaciens str. C58

38.947

79.832

0.316
T6120 Xylella fastidiosa

37.736

98.148

0.342
T10130 Escherichia coli str. K-12 substr. MC4100 strain K-12

39.806

92.793

0.35
T1044 Escherichia coli str. K-12 substr. MG1655

39.806

92.793

0.35
T137 Deinococcus radiodurans R1

38.318

91.453

0.35
T1852 Lactobacillus salivarius UCC118

41.176

74.561

0.299
T663 Streptococcus mutans UA159

30.357

100

0.291
T10090 Enterococcus faecalis ATCC 29212

33.333

84.956

0.274
T6238 Lactobacillus rhamnosus ATCC 8530

30.851

81.739

0.248
T6142 Lactobacillus rhamnosus ATCC 8530

30.851

81.739

0.248
T6137 Lactobacillus rhamnosus Lc 705

30.851

81.739

0.248
T10094 Staphylococcus aureus strain HG003 isolate RN1 Scaffold_3

29.907

89.167

0.274
T10078 Staphylococcus aureus strain HG003 isolate RN1 Scaffold_3

29.907

89.167

0.274
T1073 Staphylococcus aureus subsp. aureus N315

29.907

89.167

0.274
T612 Staphylococcus aureus subsp. aureus MW2

29.907

89.167

0.274
T6091 Staphylococcus aureus

34.146

73.214

0.239
T10177 Staphylococcus epidermidis isolate BPH0662

29.412

85

0.256
T10042 Candidatus Desulforudis audaxviator MP104C

48.718

33.051

0.162
T10131 Legionella pneumophila subsp. pneumophila str. Lorraine

28.125

90.566

0.231
T6141 Lactobacillus rhamnosus ATCC 8530

29.167

75.591

0.239
T6140 Lactobacillus rhamnosus GG

29.167

75.591

0.239
T6136 Lactobacillus rhamnosus Lc 705

29.167

75.591

0.239
T6135 Lactobacillus rhamnosus GG

29.167

75.591

0.239
T6252 Mycobacterium tuberculosis H37Rv

35.294

57.627

0.205