Detailed information of T6SS

Note: only experimentally validated proteins are displayed in the graph.


Summary

T6SS ID T6SS00161 experimental
T6SS type Type i3
Strain Azoarcus olearius
Replicon (RefSeq) chromosome (NC_008702)
Location 4242264..4289066
Function effector translocation
Comment The T6SS mutant appeared to be a better rice root colonizer as compared with the wild type.
References
[1] Boyer F et al (2009) Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 0.488888889. [PudMed:19284603]
[2] Shidore T et al (2012) Transcriptomic analysis of responses to exudates reveal genes required for rhizosphere competence of the endophyte Azoarcus sp. strain BH72. Environ Microbiol. 14(10):2775-87. [PudMed:22616609]
experimental Experimental investigation has been performed.

T6SS components and genome coordinates

ComponentFHAPAARSfa3TagJTssATssBTssCTssDTssETssFTssGTssHTssITssJTssKTssLTssM
Number11111112111111111


Component ID Component Locus tag (Gene) Coordinate Strand Size (bp) NCBI ID Product
AZO_RS19400 4238668..4239555 - 888 WP_011767588.1 transporter
AZO_RS19405 4239989..4240999 + 1011 WP_011767589.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha
AZO_RS19410 4241016..4242053 + 1038 WP_011767590.1 alpha-ketoacid dehydrogenase subunit beta
AZO_RS19415 4242264..4242509 + 246 WP_011767591.1 lipoyl domain-containing protein
AZO_RS19420 4242513..4243226 + 714 WP_011767592.1 2-oxo acid dehydrogenase subunit E2
AZO_RS19425 4243226..4243996 + 771 WP_011767593.1 lipoate--protein ligase
AZO_RS19430 4244089..4244643 + 555 WP_041644109.1 twin-arginine translocation signal domain-containing protein
AZO_RS19435 4244733..4246307 + 1575 WP_011767595.1 GMC family oxidoreductase
AZO_RS19440 4246369..4246983 + 615 WP_011767596.1 VOC family protein
T6CP012464 Sfa3 AZO_RS19445 4247215..4249182 + 1968 WP_011767597.1 sigma-54-dependent Fis family transcriptional regulator
T6CP001572 TssI AZO_RS19450 (tssI) 4249321..4251393 + 2073 WP_011767598.1 type VI secretion system tip protein VgrG
AZO_RS19455 4251398..4252432 + 1035 WP_011767599.1 DUF2169 domain-containing protein
AZO_RS20965 4252437..4253474 + 1038 WP_011767600.1 hypothetical protein
AZO_RS19465 4253497..4254504 + 1008 WP_011767601.1 AHH domain-containing protein
AZO_RS20360 4254527..4255069 + 543 WP_011767602.1 hypothetical protein
T6CP011383 PAAR AZO_RS19475 4255159..4255536 + 378 WP_011767603.1 DUF4150 domain-containing protein
AZO_RS19480 4255546..4255974 + 429 WP_011767604.1 hypothetical protein
AZO_RS19485 4255979..4257190 + 1212 WP_011767605.1 hypothetical protein
T6CP011384 FHA AZO_RS19490 (tagH) 4257210..4259045 + 1836 WP_011767606.1 type VI secretion system-associated FHA domain protein TagH
AZO_RS19495 4259097..4259867 + 771 WP_011767607.1 protein phosphatase 2C domain-containing protein
AZO_RS19500 4260004..4260594 + 591 WP_041644116.1 hypothetical protein
AZO_RS19505 4260635..4261894 + 1260 WP_011767609.1 hypothetical protein
AZO_RS19510 4261940..4263946 - 2007 WP_011767610.1 protein kinase
AZO_RS19515 (tagF) 4264005..4264712 - 708 WP_158309414.1 type VI secretion system-associated protein TagF
T6CP001573 TssM AZO_RS19520 (tssM) 4264709..4268281 - 3573 WP_011767612.1 type VI secretion system membrane subunit TssM
T6CP001574 TssL AZO_RS19525 4268313..4269617 - 1305 WP_011767613.1 DotU family type VI secretion system protein
T6CP001575 TssK AZO_RS19530 (tssK) 4269682..4271016 - 1335 WP_011767614.1 type VI secretion system baseplate subunit TssK
T6CP001576 TssJ AZO_RS19535 (tssJ) 4271065..4271583 - 519 WP_011767615.1 type VI secretion system lipoprotein TssJ
T6CP001577 TssA AZO_RS19540 (tssA) 4271852..4272913 + 1062 WP_011767616.1 type VI secretion system protein TssA
T6CP001578 TssB AZO_RS19545 (tssB) 4272962..4273471 + 510 WP_011767617.1 type VI secretion system contractile sheath small subunit
T6CP001579 TssC AZO_RS19550 (tssC) 4273523..4275019 + 1497 WP_011767618.1 type VI secretion system contractile sheath large subunit
T6CP001580 TssD AZO_RS19555 4275148..4275636 + 489 WP_011767619.1 type VI secretion system tube protein Hcp
T6CP001581 TssD AZO_RS19560 4275831..4276337 + 507 WP_011767620.1 type VI secretion system tube protein Hcp
T6CP012734 TagJ AZO_RS19565 4276353..4277174 + 822 WP_011767621.1 tetratricopeptide repeat protein
T6CP001582 TssE AZO_RS19570 (tssE) 4277194..4277676 + 483 WP_198407936.1 type VI secretion system baseplate subunit TssE
T6CP001583 TssF AZO_RS19575 (tssF) 4277775..4279646 + 1872 WP_011767623.1 type VI secretion system baseplate subunit TssF
T6CP001584 TssG AZO_RS19580 (tssG) 4279622..4280665 + 1044 WP_011767624.1 type VI secretion system baseplate subunit TssG
T6CP001585 TssH AZO_RS19585 (tssH) 4280714..4283434 + 2721 WP_011767625.1 type VI secretion system ATPase TssH
AZO_RS19590 4283535..4283924 + 390 WP_011767626.1 hypothetical protein
AZO_RS19595 4283936..4285093 + 1158 WP_011767627.1 lipase family protein
AZO_RS19600 4285131..4286267 + 1137 WP_011767628.1 hypothetical protein
AZO_RS19605 4286286..4287635 + 1350 WP_011767629.1 tetratricopeptide repeat protein
AZO_RS19610 4287636..4289066 - 1431 WP_011767630.1 serine/threonine protein kinase
AZO_RS19615 4289077..4289949 - 873 WP_011767631.1 DUF3365 domain-containing protein
AZO_RS19620 4290002..4290871 - 870 WP_041642904.1 FecR domain-containing protein
AZO_RS19625 4291053..4292258 + 1206 WP_011767633.1 beta-ketoacyl-[acyl-carrier-protein] synthase family protein
AZO_RS19630 4292263..4293090 + 828 WP_011767634.1 beta-ketoacyl synthase chain length factor
AZO_RS19635 4293195..4293596 + 402 WP_198407937.1 3-hydroxylacyl-ACP dehydratase
flank Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files

    

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Regulator ID Locus tag (Gene) Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Effector ID Locus tag (Gene) Classification Cognate immunity protein Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID
EFF00205 experimental AZO_RS19555 - - Azoarcus olearius chromosome (NC_008702) 4275148..4275636 (+) 119900186

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Immunity protein ID Locus tag (Gene) Cognate effector Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID

experimental Experimental investigation has been performed.
Accessory protein ID Locus tag (Gene) Type             Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Related structure protein Related effector