Detailed information    

insolico Bioinformatically predicted

Overview


Name   recA   Type   Machinery gene
Locus tag   P1Y72_RS05365 Genome accession   NZ_CP119599
Coordinates   1126083..1127219 (+) Length   378 a.a.
NCBI ID   WP_010922753.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 1133     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1108029..1135714 1126083..1127219 within 0


Gene organization within MGE regions


Location: 1108029..1135714
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P1Y72_RS05240 (P1Y72_05240) - 1108029..1108412 (-) 384 WP_033887760.1 ArpU family phage packaging/lysis transcriptional regulator -
  P1Y72_RS05245 (P1Y72_05245) - 1108387..1108749 (-) 363 WP_002992136.1 DUF1492 domain-containing protein -
  P1Y72_RS05250 (P1Y72_05250) - 1109153..1109641 (-) 489 WP_136243670.1 hypothetical protein -
  P1Y72_RS05255 (P1Y72_05255) - 1109715..1110224 (-) 510 WP_002992482.1 hypothetical protein -
  P1Y72_RS05260 (P1Y72_05260) - 1110226..1110399 (-) 174 WP_014635784.1 hypothetical protein -
  P1Y72_RS05265 (P1Y72_05265) - 1110405..1110578 (-) 174 WP_000694577.1 hypothetical protein -
  P1Y72_RS05270 (P1Y72_05270) - 1110865..1112553 (-) 1689 WP_002992487.1 phage/plasmid primase, P4 family -
  P1Y72_RS05275 (P1Y72_05275) - 1112522..1113379 (-) 858 WP_136098354.1 primase alpha helix C-terminal domain-containing protein -
  P1Y72_RS05280 (P1Y72_05280) - 1113380..1113652 (-) 273 WP_001100459.1 hypothetical protein -
  P1Y72_RS05285 (P1Y72_05285) - 1113655..1113984 (-) 330 WP_003058810.1 hypothetical protein -
  P1Y72_RS05290 (P1Y72_05290) - 1113996..1114187 (-) 192 WP_010922764.1 hypothetical protein -
  P1Y72_RS05295 (P1Y72_05295) - 1114190..1114411 (-) 222 WP_010922763.1 hypothetical protein -
  P1Y72_RS05300 (P1Y72_05300) - 1114408..1114740 (-) 333 WP_002992497.1 hypothetical protein -
  P1Y72_RS05305 (P1Y72_05305) - 1114985..1115506 (-) 522 WP_002992498.1 Rha family transcriptional regulator -
  P1Y72_RS05310 (P1Y72_05310) - 1115789..1115911 (-) 123 WP_002992500.1 hypothetical protein -
  P1Y72_RS05315 (P1Y72_05315) - 1115924..1116331 (-) 408 WP_002992501.1 hypothetical protein -
  P1Y72_RS05320 (P1Y72_05320) - 1116394..1116552 (-) 159 Protein_1035 helix-turn-helix transcriptional regulator -
  P1Y72_RS05325 (P1Y72_05325) - 1116586..1116792 (-) 207 WP_002992503.1 helix-turn-helix transcriptional regulator -
  P1Y72_RS05330 (P1Y72_05330) - 1116946..1117713 (+) 768 WP_003058809.1 S24 family peptidase -
  P1Y72_RS05335 (P1Y72_05335) - 1119033..1120178 (+) 1146 WP_002992191.1 site-specific integrase -
  P1Y72_RS05340 (P1Y72_05340) mutL 1120273..1122255 (+) 1983 WP_159330786.1 DNA mismatch repair endonuclease MutL -
  P1Y72_RS05345 (P1Y72_05345) - 1122266..1123486 (+) 1221 WP_010922756.1 MFS transporter -
  P1Y72_RS05350 (P1Y72_05350) ruvA 1123488..1124084 (+) 597 WP_002992186.1 Holliday junction branch migration protein RuvA -
  P1Y72_RS05355 (P1Y72_05355) - 1124094..1124654 (+) 561 WP_010922755.1 DNA-3-methyladenine glycosylase I -
  P1Y72_RS05360 (P1Y72_05360) cinA 1124723..1125994 (+) 1272 WP_010922754.1 competence/damage-inducible protein A Machinery gene
  P1Y72_RS05365 (P1Y72_05365) recA 1126083..1127219 (+) 1137 WP_010922753.1 recombinase RecA Machinery gene
  P1Y72_RS05370 (P1Y72_05370) spx 1127510..1127908 (+) 399 WP_002982188.1 transcriptional regulator Spx -
  P1Y72_RS05375 (P1Y72_05375) - 1128021..1128290 (+) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  P1Y72_RS05380 (P1Y72_05380) ruvX 1128287..1128706 (+) 420 WP_010922752.1 Holliday junction resolvase RuvX -
  P1Y72_RS05385 (P1Y72_05385) - 1128718..1129023 (+) 306 WP_002982199.1 DUF1292 domain-containing protein -
  P1Y72_RS05390 (P1Y72_05390) - 1129436..1130995 (+) 1560 WP_136273970.1 DUF2079 domain-containing protein -
  P1Y72_RS05395 (P1Y72_05395) nrdD 1131092..1133290 (+) 2199 WP_002992831.1 anaerobic ribonucleoside-triphosphate reductase -
  P1Y72_RS05400 (P1Y72_05400) - 1133472..1133618 (+) 147 WP_002982210.1 hypothetical protein -
  P1Y72_RS05405 (P1Y72_05405) - 1133647..1134582 (+) 936 WP_010922750.1 Gfo/Idh/MocA family oxidoreductase -
  P1Y72_RS05410 (P1Y72_05410) - 1134591..1135100 (+) 510 WP_011018311.1 GNAT family N-acetyltransferase -
  P1Y72_RS05415 (P1Y72_05415) nrdG 1135100..1135714 (+) 615 WP_002982219.1 anaerobic ribonucleoside-triphosphate reductase activating protein -

Sequence


Protein


Download         Length: 378 a.a.        Molecular weight: 40589.19 Da        Isoelectric Point: 4.7868

>NTDB_id=800057 P1Y72_RS05365 WP_010922753.1 1126083..1127219(+) (recA) [Streptococcus pyogenes strain 1133]
MAKKLKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGERAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGP
ESSGKTTVALHAVAQAQKEGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGNPETTPGGRALKFYASVRLDVRG
TTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAEVEIMYGEGISRTGELVKIASDLDIIQKAGAWFSYNGEKIGQGSE
NAKRYLADHPELFDEIDLKVRVKFGLLEESEEESAMAVASEETDDLALDLDNGIEIED

Nucleotide


Download         Length: 1137 bp        

>NTDB_id=800057 P1Y72_RS05365 WP_010922753.1 1126083..1127219(+) (recA) [Streptococcus pyogenes strain 1133]
TTGGCAAAAAAATTAAAAAAGAATGAAGAAATCACTAAGAAGTTTGGTGACGAACGTCGCAAAGCCCTTGATGATGCTTT
GAAAAATATTGAAAAAGATTTTGGTAAGGGTGCAGTGATGCGATTAGGAGAACGTGCAGAGCAAAAAGTTCAGGTTATGA
GTTCAGGAAGTCTAGCTCTTGATATTGCGCTTGGAGCTGGTGGTTATCCTAAAGGACGTATCATCGAAATCTATGGTCCA
GAGTCTTCCGGTAAAACGACTGTGGCTTTACATGCTGTAGCACAAGCTCAAAAAGAAGGTGGAATCGCAGCCTTTATCGA
TGCCGAGCATGCGCTTGATCCAGCTTATGCTGCTGCGCTTGGGGTTAATATTGATGAACTCCTCTTGTCTCAACCAGATT
CTGGAGAACAAGGACTTGAAATTGCAGGTAAATTGATTGATTCTGGTGCGGTTGATCTGGTTGTTGTCGATTCAGTAGCA
GCTTTAGTGCCACGTGCTGAAATTGATGGTGATATTGGCGATAGCCATGTCGGATTGCAAGCACGTATGATGAGTCAGGC
CATGCGTAAATTATCAGCTTCTATTAATAAAACAAAAACTATCGCTATCTTTATTAACCAATTGCGTGAAAAAGTTGGTG
TGATGTTTGGAAATCCTGAAACAACACCAGGTGGTCGAGCTTTGAAATTCTATGCTTCTGTTCGGCTGGATGTGCGTGGA
ACAACTCAAATTAAAGGAACTGGTGACCAAAAAGATAGCAGTATTGGTAAGGAGACCAAAATCAAGGTTGTTAAAAACAA
GGTCGCTCCGCCATTTAAGGTAGCAGAAGTTGAAATCATGTATGGGGAAGGTATTTCTCGTACAGGGGAGCTTGTGAAAA
TTGCTTCTGATTTGGACATTATCCAAAAAGCAGGTGCTTGGTTCTCTTATAATGGTGAGAAGATTGGCCAAGGTTCTGAA
AATGCTAAGCGTTATTTGGCCGATCACCCAGAATTGTTTGATGAAATCGACCTTAAAGTACGTGTTAAATTTGGTTTGCT
TGAAGAAAGCGAAGAAGAATCTGCTATGGCAGTAGCATCAGAAGAAACCGATGATCTTGCTTTAGATTTAGATAATGGTA
TTGAAATTGAAGATTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recA Streptococcus pyogenes NZ131

99.206

100

0.992

  recA Streptococcus mutans UA159

87.728

100

0.889

  recA Streptococcus mitis NCTC 12261

85.602

100

0.865

  recA Streptococcus mitis SK321

85.564

100

0.862

  recA Streptococcus pneumoniae Rx1

84.675

100

0.862

  recA Streptococcus pneumoniae D39

84.675

100

0.862

  recA Streptococcus pneumoniae R6

84.675

100

0.862

  recA Streptococcus pneumoniae TIGR4

84.675

100

0.862

  recA Lactococcus lactis subsp. cremoris KW2

78.754

93.386

0.735

  recA Latilactobacillus sakei subsp. sakei 23K

70.92

89.153

0.632

  recA Bacillus subtilis subsp. subtilis str. 168

68.085

87.037

0.593

  recA Riemerella anatipestifer ATCC 11845 = DSM 15868

62.315

89.153

0.556

  recA Acinetobacter baylyi ADP1

59.714

92.593

0.553

  recA Acinetobacter baumannii D1279779

58.924

93.386

0.55

  recA Neisseria gonorrhoeae MS11

60.35

90.741

0.548

  recA Neisseria gonorrhoeae MS11

60.35

90.741

0.548

  recA Neisseria gonorrhoeae strain FA1090

60.35

90.741

0.548

  recA Vibrio cholerae strain A1552

58.571

92.593

0.542

  recA Vibrio cholerae O1 biovar El Tor strain E7946

58.571

92.593

0.542

  recA Glaesserella parasuis strain SC1401

60

89.947

0.54

  recA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

62.848

85.45

0.537

  recA Pseudomonas stutzeri DSM 10701

57.184

92.063

0.526

  recA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

59.215

87.566

0.519

  recA Helicobacter pylori strain NCTC11637

58.383

88.36

0.516

  recA Helicobacter pylori 26695

58.383

88.36

0.516

  recA Ralstonia pseudosolanacearum GMI1000

58.133

87.831

0.511