Detailed information NTG0384545

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: HG571_RS02335
• Genome accession: NZ_CP051496
• Coordinates: 484644..487208 (-)
• Length: 854 a.a.
• NCBI ID: WP_165508558.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain PUNO-008
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 479644..492208

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HG571_RS02320 (HG571_02325)	comB10	480525..481724 (-)	1200	WP_202141022.1	DNA type IV secretion system protein ComB10	Machinery gene
HG571_RS02325 (HG571_02330)	-	481721..483352 (-)	1632	WP_202141023.1	TrbG/VirB9 family P-type conjugative transfer protein	-
HG571_RS02330 (HG571_02335)	-	483349..484515 (-)	1167	WP_202141024.1	VirB8/TrbF family protein	-
HG571_RS07940	-	484508..484642 (-)	135	WP_202147098.1	type IV secretion system protein VirB7	-
HG571_RS02335 (HG571_02340)	comB4	484644..487208 (-)	2565	WP_165508558.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
HG571_RS02340 (HG571_02345)	-	487208..487444 (-)	237	WP_202141025.1	hypothetical protein	-
HG571_RS02345 (HG571_02350)	comB3	487456..487719 (-)	264	WP_001177721.1	hypothetical protein	Machinery gene
HG571_RS02350 (HG571_02355)	comB2	487729..488019 (-)	291	WP_021176075.1	TrbC/VirB2 family protein	Machinery gene
HG571_RS02355 (HG571_02360)	-	488016..488495 (-)	480	WP_202141026.1	hypothetical protein	-
HG571_RS02360 (HG571_02365)	-	488492..488716 (-)	225	WP_000188955.1	hypothetical protein	-
HG571_RS02365 (HG571_02370)	-	488719..489507 (-)	789	WP_202141027.1	integrase	-
HG571_RS02370 (HG571_02375)	-	489562..490098 (+)	537	Protein_470	DNA adenine methylase	-
HG571_RS02375 (HG571_02380)	-	490101..490726 (+)	626	Protein_471	GIY-YIG nuclease family protein	-
HG571_RS02380 (HG571_02385)	-	490817..491872 (+)	1056	WP_202141028.1	DNA cytosine methyltransferase	-

Sequence

Protein

• Length: 854 a.a.
• Molecular weight: 98199.11 Da
• Isoelectric Point: 8.5018

>NTDB_id=384545 HG571_RS02335 WP_165508558.1 484644..487208(-) (comB4) [Helicobacter pylori strain PUNO-008]
MLENAFKYCKEKAIELLTGFVPKTYSMAEECNILGLYDDTFIITKQENLVAIMSLQGLSYSNLMQKDLEGYFDTRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNPYAKAIITQFESKEIYKTEYFLVFESITSNVKSFFEKKKLEMTTSINEELEES
SKENENNSNETHSNTSSKKDKKNKFKKKTTFSATSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKYIAFN
PKLKRLSDSYIASNVHFKKDYFVIEFQNQSTFCACVGIKNYESEEISSLPISTLLHTQIELDLIFHIRSLGQFESLNFLK
TKKKLTLSKIVKNDIDDYIELVQANRLSMQECALNLVIRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKPSYFSFFP
NNANINPRMRNQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGHTMII
GATGAGKTTLISYLMMSALKYSNIDILALDRLNGLYSFTKYFDGIYNQGENFHINPFSLEDSATNRAFLLHFYAQMAKVD
SYDDHKDKVEDKTALINAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNAIVKTNTNILDSSFEDYLKSSLFSSRMDS
LDFKTRISTINTDSILHNDDDAGLLAYYVFHKMIDRALKINRGFLCFIDEFKSYAQNEMMNKKINEIITQARKANGVIVL
ALQDINQLTEVRNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNIIDVSL
SSLGNYLQIFSSNSSMVEHIENLIKHYPTTWREVFVNNTYQKFDDKKHLETVLA

Nucleotide

• Length: 2565 bp

>NTDB_id=384545 HG571_RS02335 WP_165508558.1 484644..487208(-) (comB4) [Helicobacter pylori strain PUNO-008]
ATGCTAGAAAACGCTTTTAAATATTGCAAAGAGAAAGCCATAGAGCTTTTAACAGGTTTTGTGCCAAAAACCTATTCTAT
GGCAGAAGAATGCAATATTTTAGGCTTGTATGATGATACTTTTATTATCACCAAACAAGAAAATTTAGTCGCTATTATGT
CTTTACAAGGACTAAGTTATTCTAATTTAATGCAAAAAGATTTGGAGGGCTATTTTGATACAAGACAAAATGTTCTCAAT
ACCATTAGTAAGGACATTCAATTAAGGATTGTGGCTAAAAGGCGTAAAGAATTTATCAATCAAAGCCCCAACATTGACAA
CCCTTATGCCAAAGCCATTATCACACAATTTGAAAGCAAGGAAATCTATAAAACAGAATATTTTTTAGTGTTTGAGAGCA
TTACTTCTAATGTCAAATCTTTCTTTGAGAAAAAGAAATTAGAAATGACTACTTCAATCAATGAAGAATTAGAAGAAAGC
TCTAAAGAGAATGAAAATAACTCCAATGAGACCCATTCAAACACAAGCTCTAAAAAAGACAAGAAAAACAAGTTCAAAAA
AAAGACAACCTTTAGCGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTGAAAAACGCATTAAGAGAGT
TTAAACCCACTCTCTTAAATTCTAAAGAAGTGTTGAATTTCTATGCGGAGTATATCAATGGCAAATACATCGCCTTTAAT
CCTAAATTAAAGCGACTAAGCGATAGCTATATTGCTAGTAATGTGCATTTTAAAAAAGATTACTTTGTCATTGAATTTCA
AAATCAAAGCACCTTTTGTGCGTGTGTGGGTATCAAAAACTATGAGAGTGAAGAAATTTCTTCTCTCCCAATTTCTACCC
TTTTACACACGCAAATTGAATTAGATTTAATCTTTCATATCCGTTCATTAGGGCAGTTTGAAAGCTTGAATTTTCTAAAA
ACCAAGAAAAAACTCACGCTTTCTAAAATAGTGAAAAATGATATTGATGATTATATAGAATTGGTGCAAGCCAATCGTTT
GAGTATGCAAGAGTGCGCCTTAAACTTAGTTATAAGAGCTAAGAGCAAAGCCAAATTAGACAAATCTTTAAAAGAGATTT
TATCCTTGCTTAATAACGCTGGACTAGGCAGTGTTACAGAAACCATAGGGCTAAAACCCTCTTATTTTTCATTCTTCCCT
AATAATGCAAACATTAACCCTAGAATGAGAAATCAAACTTCCCAAGTGATAGCCTCTTTAATCTTGTTTGAAAAAAATAA
TACAGGTTTTAGGGCAAATTCTTGGGGCGATATGCCTTTATCTGTGTTTAAGAACCTAGACCATAGCCCTTATTTGTTTA
ACTTCCACAACCAAGAAGTCAAACATAAAGGCGTGTTAGCCCATAATGTTGCACGAGTGGTAGGGCATACGATGATTATA
GGAGCAACAGGAGCTGGTAAAACCACGCTCATTAGCTATCTAATGATGAGCGCTTTAAAATACTCTAACATTGATATTCT
AGCTCTTGATAGATTAAATGGTTTGTATTCTTTTACCAAGTATTTTGATGGGATTTATAATCAAGGCGAAAACTTTCATA
TCAATCCTTTTTCATTAGAAGATAGTGCAACTAATAGAGCCTTTTTATTGCATTTTTATGCCCAAATGGCAAAAGTGGAT
AGCTATGATGACCATAAAGATAAAGTAGAAGATAAAACAGCCCTAATAAATGCTATTGATACCATGTATAGAAATTATAA
CGATGAAGTCAAACAAGCCAAATTTAGCAACCAAGAATTACCCCTTCCTTTTGATTTAAAAGAGTTTGTCAATGCCATTG
TTAAAACCAATACAAACATTTTAGATAGTAGTTTTGAAGACTATTTAAAATCTTCCTTATTTTCTAGCCGAATGGATAGC
CTAGATTTTAAAACTCGCATTAGCACCATAAATACCGATAGCATTTTACATAATGATGATGACGCTGGGCTTTTAGCCTA
CTATGTGTTTCATAAGATGATTGATAGAGCCTTGAAAATCAATCGTGGTTTTTTATGCTTTATTGATGAATTTAAATCTT
ACGCTCAAAATGAAATGATGAATAAAAAAATCAATGAAATCATTACCCAAGCCAGAAAGGCTAATGGGGTGATTGTTCTA
GCCTTACAAGACATTAACCAGCTAACTGAAGTGAGAAACGCTCAAAGCTTTATTAAAAATATGGGGCAGTTGATTTTGTA
TCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTGAGCGATACTGAAAAGCATTTTTTAG
AAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAATATTATAGATGTGAGCCTT
AGCTCTTTGGGTAATTACTTACAAATCTTTAGCTCTAATTCTAGCATGGTAGAACACATTGAAAATCTCATTAAGCATTA
CCCTACTACTTGGAGAGAAGTCTTTGTCAATAACACCTATCAAAAATTTGATGATAAAAAACACTTAGAAACGGTGCTTG
CCTAA

Domains

Predicted by InterProScan.

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (210-408)

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (433-501)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	47.129	97.892	0.461