Detailed information    

insolico Bioinformatically predicted

Overview

Name   recA   Type   Machinery gene
Locus tag   EQH44_RS09020 Genome accession   NZ_CP035236
Coordinates   1781975..1783141 (-) Length   388 a.a.
NCBI ID   WP_001085461.1    Uniprot ID   A0A0I7UWZ4
Organism   Streptococcus pneumoniae strain TVO_1902282     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1776294..1798288 1781975..1783141 within 0


Gene organization within MGE regions


Location: 1776294..1798288
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH44_RS08985 (EQH44_09500) - 1776294..1776878 (-) 585 WP_001101186.1 hypothetical protein -
  EQH44_RS08990 (EQH44_09505) - 1777276..1777701 (-) 426 WP_001812209.1 hypothetical protein -
  EQH44_RS08995 (EQH44_09510) - 1777830..1778189 (-) 360 WP_000749819.1 ImmA/IrrE family metallo-endopeptidase -
  EQH44_RS09000 (EQH44_09515) - 1778235..1778441 (-) 207 WP_000366093.1 hypothetical protein -
  EQH44_RS09005 (EQH44_09520) - 1778428..1778589 (-) 162 WP_000289348.1 helix-turn-helix domain-containing protein -
  EQH44_RS09010 (EQH44_09525) lytA 1778967..1779923 (-) 957 WP_000405234.1 N-acetylmuramoyl-L-alanine amidase LytA -
  EQH44_RS09015 (EQH44_09530) - 1780299..1781669 (-) 1371 WP_001036255.1 MATE family efflux transporter -
  EQH44_RS09020 (EQH44_09540) recA 1781975..1783141 (-) 1167 WP_001085461.1 recombinase RecA Machinery gene
  EQH44_RS09025 (EQH44_09545) cinA 1783196..1784452 (-) 1257 WP_000642709.1 competence/damage-inducible protein A Machinery gene
  EQH44_RS09030 (EQH44_09550) brpA 1784537..1785553 (-) 1017 WP_000239282.1 biofilm formation/cell division transcriptional regulator BrpA -
  EQH44_RS09035 (EQH44_09555) - 1785561..1786079 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  EQH44_RS09040 (EQH44_09560) tsaE 1786069..1786512 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  EQH44_RS09045 (EQH44_09565) comM 1786598..1787218 (-) 621 WP_000839908.1 hypothetical protein Regulator
  EQH44_RS09050 (EQH44_09575) - 1787601..1788464 (-) 864 WP_001093624.1 helix-turn-helix domain-containing protein -
  EQH44_RS10755 (EQH44_09580) - 1788656..1788826 (+) 171 WP_001227862.1 PhrA family quorum-sensing system peptide -
  EQH44_RS09055 (EQH44_09585) pneA1 1788929..1789153 (+) 225 WP_000181087.1 two-peptide bacteriocin subunit PneA1 -
  EQH44_RS09060 (EQH44_09590) pneA2 1789160..1789348 (+) 189 WP_000786759.1 two-peptide bacteriocin subunit PneA2 -
  EQH44_RS09065 lanM 1789465..1791396 (+) 1932 WP_001812208.1 type 2 lanthipeptide synthetase LanM -
  EQH44_RS09070 - 1791446..1792456 (+) 1011 WP_001812207.1 lanthionine synthetase LanC family protein -
  EQH44_RS09075 (EQH44_09600) - 1792806..1793510 (+) 705 WP_001033170.1 flavodoxin family protein -
  EQH44_RS09080 (EQH44_09605) - 1793491..1794420 (+) 930 WP_000912954.1 M50 family metallopeptidase -
  EQH44_RS09085 (EQH44_09610) - 1794417..1796525 (+) 2109 WP_000701298.1 peptidase domain-containing ABC transporter -
  EQH44_RS09090 (EQH44_09615) - 1796549..1798288 (+) 1740 WP_000699969.1 S8 family serine peptidase -

Sequence

Protein


Download         Length: 388 a.a.        Molecular weight: 41925.71 Da        Isoelectric Point: 4.8403

>NTDB_id=336763 EQH44_RS09020 WP_001085461.1 1781975..1783141(-) (recA) [Streptococcus pneumoniae strain TVO_1902282]
MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGERAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGP
ESSGKTTVALHAVAQAQKEGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGNPETTPGGRALKFYASVRLDVRG
NTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAVVEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSE
NAKKYLAEHPEIFDEIDKQVRSKFGLIDGEEASEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE

Nucleotide


Download         Length: 1167 bp        

>NTDB_id=336763 EQH44_RS09020 WP_001085461.1 1781975..1783141(-) (recA) [Streptococcus pneumoniae strain TVO_1902282]
ATGGCGAAAAAACCAAAAAAATTAGAAGAAATTTCAAAAAAATTTGGGGCAGAACGTGAAAAGGCCTTGAATGACGCTCT
TAAATTGATTGAGAAAGACTTTGGTAAAGGATCAATCATGCGTTTGGGTGAACGTGCGGAGCAAAAGGTGCAAGTGATGA
GCTCAGGTTCTTTAGCTCTTGACATTGCCCTTGGCTCAGGTGGTTATCCTAAGGGACGTATCATCGAAATCTATGGCCCA
GAGTCATCTGGTAAGACAACGGTTGCCCTTCATGCAGTTGCACAAGCGCAAAAAGAAGGTGGGATTGCTGCCTTTATCGA
TGCGGAACATGCCCTTGATCCAGCTTATGCTGCGGCCCTTGGTGTCAATATTGACGAATTGCTCTTGTCTCAACCAGACT
CAGGAGAGCAAGGTCTTGAAATTGCGGGAAAATTGATTGACTCAGGTGCAGTTGATCTTGTCGTAGTCGACTCAGTTGCT
GCCCTTGTTCCTCGTGCGGAAATTGATGGAGATATCGGAGATAGCCATGTTGGTTTGCAGGCTCGTATGATGAGCCAGGC
CATGCGTAAACTTGGCGCCTCTATCAATAAAACCAAAACAATTGCCATTTTTATCAACCAATTGCGTGAAAAAGTTGGAG
TGATGTTTGGAAATCCAGAAACAACACCGGGCGGACGTGCTTTGAAATTCTATGCTTCAGTCCGCTTGGATGTTCGTGGT
AATACACAAATTAAGGGAACTGGTGACCAAAAAGAAACCAATGTCGGTAAAGAAACTAAGATTAAGGTTGTAAAAAATAA
GGTAGCTCCACCGTTTAAGGAAGCCGTAGTTGAAATTATGTACGGAGAAGGAATTTCTAAGACTGGTGAGCTTTTGAAGA
TTGCAAGCGATTTGGATATTATCAAAAAAGCAGGGGCTTGGTATTCTTACAAAGATGAAAAAATTGGGCAAGGTTCTGAG
AATGCTAAGAAATACTTGGCAGAGCACCCAGAAATCTTTGATGAAATTGATAAGCAAGTCCGTTCTAAATTTGGCTTGAT
TGATGGAGAAGAAGCTTCAGAACAAGATACTGAAAACAAAAAAGATGAGCCAAAGAAAGAAGAAGCAGTGAATGAAGAAG
TTACGCTTGACTTAGGCGATGAACTTGAAATCGAAATTGAAGAATAA

Domains

Predicted by InterproScan.

recA bacterial DNA recombination protein (RecA)

(21-286)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0I7UWZ4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recA Streptococcus pneumoniae Rx1

99.485

100

0.995
  recA Streptococcus pneumoniae D39

99.485

100

0.995
  recA Streptococcus pneumoniae R6

99.485

100

0.995
  recA Streptococcus pneumoniae TIGR4

99.485

100

0.995
  recA Streptococcus mitis NCTC 12261

94.33

100

0.943
  recA Streptococcus mitis SK321

94.072

100

0.941
  recA Streptococcus mutans UA159

83.204

99.742

0.83
  recA Streptococcus pyogenes NZ131

90.725

88.918

0.807
  recA Lactococcus lactis subsp. cremoris KW2

78.125

90.722

0.709
  recA Latilactobacillus sakei subsp. sakei 23K

67.63

89.175

0.603
  recA Bacillus subtilis subsp. subtilis str. 168

68.788

85.052

0.585
  recA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

64.706

83.247

0.539
  recA Glaesserella parasuis strain SC1401

60.641

88.402

0.536
  recA Neisseria gonorrhoeae MS11

59.706

87.629

0.523
  recA Neisseria gonorrhoeae strain FA1090

59.706

87.629

0.523
  recA Neisseria gonorrhoeae MS11

59.706

87.629

0.523
  recA Vibrio cholerae strain A1552

62.848

83.247

0.523
  recA Vibrio cholerae O1 biovar El Tor strain E7946

62.848

83.247

0.523
  recA Acinetobacter baumannii D1279779

61.963

84.021

0.521
  recA Riemerella anatipestifer ATCC 11845 = DSM 15868

60.725

85.309

0.518
  recA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.824

87.629

0.515
  recA Acinetobacter baylyi ADP1

61.35

84.021

0.515
  recA Helicobacter pylori strain NCTC11637

56.125

90.464

0.508
  recA Helicobacter pylori 26695

56.125

90.464

0.508
  recA Pseudomonas stutzeri DSM 10701

59.509

84.021

0.5
  recA Ralstonia pseudosolanacearum GMI1000

59.937

81.701

0.49

Multiple sequence alignment