Detailed information    

insolico Bioinformatically predicted

Overview


Name   cipB   Type   Regulator
Locus tag   ES276_RS04640 Genome accession   NZ_CP038252
Coordinates   891950..892099 (+) Length   49 a.a.
NCBI ID   WP_001818346.1    Uniprot ID   Q9FBH1
Organism   Streptococcus pneumoniae strain TVO_1901936     
Function   indirect induction of ComX; activation of comRS system (predicted from homology)   
Competence regulation

Genomic Context


Location: 886950..897099
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES276_RS10930 (ES276_04940) comA/nlmT 886993..887580 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  ES276_RS04595 (ES276_04945) blpI 887860..888057 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  ES276_RS04600 (ES276_04955) blpJ 888524..888793 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  ES276_RS04605 (ES276_04960) blpU 888862..889092 (+) 231 WP_000379967.1 bacteriocin-like peptide BlpU -
  ES276_RS04610 (ES276_04965) - 889095..889214 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  ES276_RS04615 (ES276_04970) - 889511..889675 (+) 165 WP_000727118.1 hypothetical protein -
  ES276_RS04620 (ES276_04975) - 889672..890076 (+) 405 WP_000846943.1 hypothetical protein -
  ES276_RS04625 (ES276_04980) - 890279..891083 (+) 805 WP_100214365.1 IS5 family transposase -
  ES276_RS04630 (ES276_04985) blpM 891233..891487 (+) 255 WP_000379879.1 two-peptide bacteriocin subunit BlpM -
  ES276_RS04635 (ES276_04990) blpN 891503..891706 (+) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  ES276_RS04640 (ES276_05000) cipB 891950..892099 (+) 150 WP_001818346.1 bacteriocin-like peptide BlpO Regulator
  ES276_RS04645 (ES276_05005) - 892203..892322 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  ES276_RS04650 (ES276_05010) - 893107..893490 (+) 384 WP_000877381.1 hypothetical protein -
  ES276_RS04655 (ES276_05015) - 893542..894231 (+) 690 WP_000760538.1 CPBP family intramembrane glutamic endopeptidase -
  ES276_RS04660 (ES276_05020) blpZ 894273..894506 (+) 234 WP_000276498.1 immunity protein BlpZ -
  ES276_RS04665 (ES276_05030) - 894657..895268 (+) 612 WP_000394045.1 CPBP family intramembrane glutamic endopeptidase -
  ES276_RS04670 (ES276_05035) ccrZ 895429..896223 (+) 795 WP_000363002.1 cell cycle regulator CcrZ -
  ES276_RS04675 (ES276_05040) trmB 896220..896855 (+) 636 WP_001266083.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -

Sequence


Protein


Download         Length: 49 a.a.        Molecular weight: 5134.91 Da        Isoelectric Point: 3.9133

>NTDB_id=310225 ES276_RS04640 WP_001818346.1 891950..892099(+) (cipB) [Streptococcus pneumoniae strain TVO_1901936]
MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDGCATTV

Nucleotide


Download         Length: 150 bp        

>NTDB_id=310225 ES276_RS04640 WP_001818346.1 891950..892099(+) (cipB) [Streptococcus pneumoniae strain TVO_1901936]
ATGGATACAAAAATGATGTCACAATTTGCAGTTATGGATAATGAAATGCTTGCTTGCGTTGAAGGTGGAGATATTGATTG
GGGAAGAAAAATTAGTTGTGCAGCAGGGGTTGCATATGGCGCAATTGATGGGTGTGCAACAACGGTTTGA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q9FBH1

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cipB Streptococcus mutans UA159

51.02

100

0.51


Multiple sequence alignment