Detailed information
Bioinformatically predicted
Overview
| Name | comR/comR2 | Type | Regulator |
| Locus tag | DQL23_RS10665 | Genome accession | NZ_LS483341 |
| Coordinates | 2169631..2170113 (-) | Length | 160 a.a. |
| NCBI ID | WP_045772576.1 | Uniprot ID | A0A0F3HQT1 |
| Organism | Streptococcus gordonii strain NCTC7865 | ||
| Function | activate transcription of late competence genes (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 2161911..2187408 | 2169631..2170113 | within | 0 |
Gene organization within MGE regions
Location: 2161911..2187408
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DQL23_RS10555 (NCTC7865_02129) | mreC | 2161911..2162726 (-) | 816 | WP_060554277.1 | rod shape-determining protein MreC | - |
| DQL23_RS10560 (NCTC7865_02129) | - | 2162794..2162881 (-) | 88 | WP_060554277.1 | tRNA-Ser | - |
| DQL23_RS10565 (NCTC7865_02129) | - | 2162892..2162965 (-) | 74 | WP_060554277.1 | tRNA-Ile | - |
| DQL23_RS10570 (NCTC7865_02129) | - | 2163001..2163071 (-) | 71 | WP_060554277.1 | tRNA-Gly | - |
| DQL23_RS10575 (NCTC7865_02129) | - | 2163085..2163157 (-) | 73 | WP_060554277.1 | tRNA-Phe | - |
| DQL23_RS10580 (NCTC7865_02129) | - | 2163161..2163234 (-) | 74 | WP_060554277.1 | tRNA-Met | - |
| DQL23_RS10585 (NCTC7865_02129) | - | 2163254..2163343 (-) | 90 | WP_060554277.1 | tRNA-Ser | - |
| DQL23_RS10590 (NCTC7865_02129) | - | 2163360..2163433 (-) | 74 | WP_060554277.1 | tRNA-Ile | - |
| DQL23_RS10595 (NCTC7865_02129) | - | 2163447..2163520 (-) | 74 | WP_060554277.1 | tRNA-Met | - |
| DQL23_RS10600 (NCTC7865_02129) | - | 2163527..2163600 (-) | 74 | WP_060554277.1 | tRNA-Pro | - |
| DQL23_RS10605 (NCTC7865_02129) | - | 2163629..2163702 (-) | 74 | WP_060554277.1 | tRNA-Arg | - |
| DQL23_RS10610 (NCTC7865_02129) | - | 2163716..2163801 (-) | 86 | WP_060554277.1 | tRNA-Leu | - |
| DQL23_RS10615 (NCTC7865_02129) | - | 2163807..2163878 (-) | 72 | WP_060554277.1 | tRNA-Gly | - |
| DQL23_RS10620 (NCTC7865_02129) | - | 2163899..2163971 (-) | 73 | WP_060554277.1 | tRNA-Thr | - |
| DQL23_RS10625 (NCTC7865_02129) | - | 2163982..2164063 (-) | 82 | WP_060554277.1 | tRNA-Leu | - |
| DQL23_RS10630 (NCTC7865_02129) | - | 2164069..2164141 (-) | 73 | WP_060554277.1 | tRNA-Lys | - |
| DQL23_RS10635 (NCTC7865_02129) | - | 2164169..2164241 (-) | 73 | WP_060554277.1 | tRNA-Asp | - |
| DQL23_RS10640 (NCTC7865_02129) | - | 2164244..2164316 (-) | 73 | WP_060554277.1 | tRNA-Val | - |
| DQL23_RS10645 (NCTC7865_02129) | rrf | 2164449..2164564 (-) | 116 | WP_060554277.1 | 5S ribosomal RNA | - |
| DQL23_RS10650 (NCTC7865_02129) | - | 2164645..2167544 (-) | 2900 | WP_060554277.1 | 23S ribosomal RNA | - |
| DQL23_RS10655 (NCTC7865_02129) | - | 2167664..2167736 (-) | 73 | WP_060554277.1 | tRNA-Ala | - |
| DQL23_RS10660 (NCTC7865_02129) | - | 2167791..2169347 (-) | 1557 | WP_060554277.1 | 16S ribosomal RNA | - |
| DQL23_RS10665 (NCTC7865_02151) | comR/comR2 | 2169631..2170113 (-) | 483 | WP_045772576.1 | sigma-70 family RNA polymerase sigma factor | Regulator |
| DQL23_RS10670 (NCTC7865_02151) | - | 2170315..2170388 (-) | 74 | WP_045772576.1 | tRNA-Asn | - |
| DQL23_RS10675 (NCTC7865_02151) | - | 2170394..2170465 (-) | 72 | WP_045772576.1 | tRNA-Glu | - |
| DQL23_RS10680 (NCTC7865_02154) | ftsH | 2170642..2172624 (-) | 1983 | WP_060553302.1 | ATP-dependent zinc metalloprotease FtsH | - |
| DQL23_RS10685 (NCTC7865_02155) | hpt | 2172643..2173185 (-) | 543 | WP_060553301.1 | hypoxanthine phosphoribosyltransferase | - |
| DQL23_RS10690 (NCTC7865_02156) | tilS | 2173190..2174467 (-) | 1278 | WP_060553300.1 | tRNA lysidine(34) synthetase TilS | - |
| DQL23_RS10695 (NCTC7865_02157) | - | 2174464..2175744 (-) | 1281 | WP_045772579.1 | serine hydrolase | - |
| DQL23_RS10700 | - | 2175744..2175863 (-) | 120 | WP_037622626.1 | SP_0009 family protein | - |
| DQL23_RS10705 (NCTC7865_02158) | - | 2175866..2176234 (-) | 369 | WP_012131073.1 | FtsB family cell division protein | - |
| DQL23_RS10710 (NCTC7865_02159) | - | 2176227..2176493 (-) | 267 | WP_012131074.1 | RNA-binding S4 domain-containing protein | - |
| DQL23_RS10715 (NCTC7865_02160) | mfd | 2176559..2180062 (-) | 3504 | WP_111705915.1 | transcription-repair coupling factor | - |
| DQL23_RS10720 (NCTC7865_02161) | pth | 2180055..2180624 (-) | 570 | WP_060553299.1 | aminoacyl-tRNA hydrolase | - |
| DQL23_RS10725 (NCTC7865_02162) | ychF | 2180698..2181813 (-) | 1116 | WP_008808030.1 | redox-regulated ATPase YchF | - |
| DQL23_RS10730 (NCTC7865_02162) | - | 2181923..2181996 (-) | 74 | WP_008808030.1 | tRNA-Asn | - |
| DQL23_RS10735 (NCTC7865_02162) | - | 2182002..2182073 (-) | 72 | WP_008808030.1 | tRNA-Glu | - |
| DQL23_RS10740 (NCTC7865_02165) | comE/comE2 | 2182135..2182902 (-) | 768 | WP_008808031.1 | competence system response regulator transcription factor ComE | Regulator |
| DQL23_RS10745 (NCTC7865_02166) | comD/comD2 | 2182899..2184257 (-) | 1359 | WP_060553298.1 | competence system sensor histidine kinase ComD | Regulator |
| DQL23_RS10750 (NCTC7865_02167) | comC/comC2 | 2184273..2184425 (-) | 153 | WP_008808033.1 | bacteriocin | Regulator |
| DQL23_RS10755 (NCTC7865_02167) | - | 2184596..2184669 (-) | 74 | WP_008808033.1 | tRNA-Arg | - |
| DQL23_RS10760 (NCTC7865_02169) | rlmH | 2184712..2185191 (-) | 480 | WP_060553297.1 | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH | - |
| DQL23_RS10765 (NCTC7865_02170) | htrA | 2185385..2186578 (+) | 1194 | WP_060553296.1 | S1C family serine protease | Regulator |
| DQL23_RS10770 (NCTC7865_02171) | spo0J | 2186644..2187408 (+) | 765 | WP_045772585.1 | ParB/RepB/Spo0J family partition protein | Regulator |
Sequence
Protein
Download Length: 160 a.a. Molecular weight: 19931.87 Da Isoelectric Point: 9.4703
>NTDB_id=1137512 DQL23_RS10665 WP_045772576.1 2169631..2170113(-) (comR/comR2) [Streptococcus gordonii strain NCTC7865]
MKFEDVYKQVEGIVKRCYKDYYLHLWEYADWRQEGMLVLYELLKSHPNLLEDHPRLYRYFKTKFRNRIHDLIRRQESQKR
KLDRQPYEEVSEIGHRLRMKELYLDELVAFRSAMAEYRSQLSPEESKQYERLMADERFKGRKAMLKDLSYHLRDFNPRLD
MKFEDVYKQVEGIVKRCYKDYYLHLWEYADWRQEGMLVLYELLKSHPNLLEDHPRLYRYFKTKFRNRIHDLIRRQESQKR
KLDRQPYEEVSEIGHRLRMKELYLDELVAFRSAMAEYRSQLSPEESKQYERLMADERFKGRKAMLKDLSYHLRDFNPRLD
Nucleotide
Download Length: 483 bp
>NTDB_id=1137512 DQL23_RS10665 WP_045772576.1 2169631..2170113(-) (comR/comR2) [Streptococcus gordonii strain NCTC7865]
ATGAAGTTTGAGGACGTATACAAACAAGTTGAAGGGATAGTCAAGCGCTGTTATAAAGATTATTATCTGCACTTATGGGA
GTATGCAGATTGGAGGCAGGAAGGAATGTTGGTGTTGTACGAATTATTAAAAAGTCATCCCAACCTACTGGAAGATCATC
CACGCCTGTACCGTTACTTCAAGACCAAGTTTCGGAACAGAATTCATGATTTGATTCGTCGCCAAGAGAGTCAAAAGCGG
AAATTGGACAGGCAACCCTATGAAGAGGTCAGCGAGATAGGTCATCGTTTAAGAATGAAAGAGCTGTATCTGGATGAATT
GGTAGCCTTTAGAAGTGCAATGGCAGAGTATAGAAGTCAGCTCAGTCCAGAAGAATCAAAACAATATGAGCGTCTGATGG
CAGATGAAAGGTTCAAAGGACGTAAGGCAATGCTCAAAGATTTGTCCTACCACTTAAGGGATTTCAATCCCCGTTTAGAT
TAA
ATGAAGTTTGAGGACGTATACAAACAAGTTGAAGGGATAGTCAAGCGCTGTTATAAAGATTATTATCTGCACTTATGGGA
GTATGCAGATTGGAGGCAGGAAGGAATGTTGGTGTTGTACGAATTATTAAAAAGTCATCCCAACCTACTGGAAGATCATC
CACGCCTGTACCGTTACTTCAAGACCAAGTTTCGGAACAGAATTCATGATTTGATTCGTCGCCAAGAGAGTCAAAAGCGG
AAATTGGACAGGCAACCCTATGAAGAGGTCAGCGAGATAGGTCATCGTTTAAGAATGAAAGAGCTGTATCTGGATGAATT
GGTAGCCTTTAGAAGTGCAATGGCAGAGTATAGAAGTCAGCTCAGTCCAGAAGAATCAAAACAATATGAGCGTCTGATGG
CAGATGAAAGGTTCAAAGGACGTAAGGCAATGCTCAAAGATTTGTCCTACCACTTAAGGGATTTCAATCCCCGTTTAGAT
TAA
Domains
No domain identified.
Similar proteins
Only experimentally validated proteins are listed.