Detailed information    

insolico Bioinformatically predicted

Overview

Name   recA   Type   Machinery gene
Locus tag   EW023_RS09280 Genome accession   NZ_LR130239
Coordinates   1831468..1832604 (-) Length   378 a.a.
NCBI ID   WP_023612576.1    Uniprot ID   A0A5S4TE17
Organism   Streptococcus pyogenes strain PS003 isolate PS003     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1826468..1837604
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW023_RS09255 - 1827689..1829248 (-) 1560 WP_023612610.1 hypothetical protein -
  EW023_RS09260 - 1829662..1829967 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  EW023_RS09265 ruvX 1829979..1830398 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  EW023_RS09270 - 1830395..1830664 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  EW023_RS09275 spx 1830779..1831177 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  EW023_RS09280 recA 1831468..1832604 (-) 1137 WP_023612576.1 recombinase RecA Machinery gene
  EW023_RS09285 cinA 1832693..1833964 (-) 1272 WP_050336413.1 competence/damage-inducible protein A Machinery gene
  EW023_RS09290 - 1834033..1834593 (-) 561 WP_023611248.1 DNA-3-methyladenine glycosylase I -
  EW023_RS09295 ruvA 1834603..1835199 (-) 597 WP_023612588.1 Holliday junction branch migration protein RuvA -
  EW023_RS09300 - 1835201..1836421 (-) 1221 WP_002992187.1 MDR family MFS transporter -

Sequence

Protein


Download         Length: 378 a.a.        Molecular weight: 40632.21 Da        Isoelectric Point: 4.8451

>NTDB_id=1116699 EW023_RS09280 WP_023612576.1 1831468..1832604(-) (recA) [Streptococcus pyogenes strain PS003 isolate PS003]
MAKKLKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGERAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGP
ESSGKTTVALHAVAQAQKEGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGNPETTPGGRALKFYASVRLDVRG
TTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAEVEIMYGEGISRTGELVKIASDLDIIQKAGAWFSYNGEKIGQGSE
NAKRYLADHPELFDEIDRKVRVKFGLLEESEEESAMAVASEETDDLALDLDNGIEIED

Nucleotide


Download         Length: 1137 bp        

>NTDB_id=1116699 EW023_RS09280 WP_023612576.1 1831468..1832604(-) (recA) [Streptococcus pyogenes strain PS003 isolate PS003]
TTGGCAAAAAAATTAAAAAAGAATGAAGAAATCACTAAGAAGTTTGGTGACGAACGTCGCAAAGCCCTTGATGATGCTTT
GAAAAATATTGAAAAAGATTTTGGTAAGGGCGCAGTGATGCGATTAGGAGAACGTGCAGAGCAAAAAGTTCAGGTTATGA
GTTCAGGAAGTCTAGCTCTTGATATTGCGCTTGGAGCTGGTGGTTATCCTAAAGGACGTATCATCGAAATCTATGGTCCA
GAGTCTTCCGGTAAAACGACTGTGGCTTTACATGCTGTAGCACAAGCTCAAAAAGAAGGTGGAATCGCAGCCTTTATCGA
TGCCGAGCATGCGCTTGATCCAGCTTATGCTGCTGCGCTTGGGGTTAATATTGATGAACTCCTCTTGTCTCAACCAGATT
CTGGAGAACAAGGACTTGAAATTGCAGGTAAATTGATTGATTCTGGTGCGGTTGATCTGGTTGTTGTCGATTCAGTAGCA
GCTTTAGTGCCACGTGCTGAAATTGATGGTGATATTGGCGATAGCCATGTCGGATTGCAAGCACGTATGATGAGTCAGGC
CATGCGTAAATTATCAGCTTCTATTAATAAAACAAAAACTATCGCTATCTTTATTAACCAATTGCGTGAAAAAGTTGGTG
TGATGTTTGGAAATCCTGAAACAACACCAGGTGGTCGAGCTTTGAAATTCTATGCTTCTGTTCGGCTGGATGTCCGTGGA
ACAACTCAAATTAAAGGAACTGGTGACCAAAAAGATAGCAGCATTGGTAAGGAGACCAAAATCAAGGTTGTTAAAAACAA
GGTCGCTCCGCCATTTAAGGTAGCAGAAGTTGAAATCATGTATGGGGAAGGTATTTCTCGTACAGGGGAGCTTGTGAAAA
TTGCTTCTGATTTGGACATTATCCAAAAAGCAGGTGCTTGGTTCTCTTATAATGGTGAGAAGATTGGCCAAGGTTCTGAA
AATGCTAAGCGTTATTTGGCCGATCATCCAGAATTGTTTGATGAAATCGACCGTAAAGTACGTGTTAAATTTGGTTTGCT
TGAAGAAAGCGAAGAAGAATCTGCTATGGCAGTAGCATCAGAAGAAACCGATGATCTTGCTTTAGATTTAGATAATGGTA
TTGAAATTGAAGATTAA

Domains

Predicted by InterproScan.

recA bacterial DNA recombination protein (RecA)

(21-286)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5S4TE17

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recA Streptococcus pyogenes NZ131

99.471

100

0.995
  recA Streptococcus mutans UA159

87.728

100

0.889
  recA Streptococcus mitis NCTC 12261

85.602

100

0.865
  recA Streptococcus mitis SK321

85.564

100

0.862
  recA Streptococcus pneumoniae Rx1

84.675

100

0.862
  recA Streptococcus pneumoniae D39

84.675

100

0.862
  recA Streptococcus pneumoniae R6

84.675

100

0.862
  recA Streptococcus pneumoniae TIGR4

84.675

100

0.862
  recA Lactococcus lactis subsp. cremoris KW2

78.754

93.386

0.735
  recA Latilactobacillus sakei subsp. sakei 23K

70.623

89.153

0.63
  recA Bacillus subtilis subsp. subtilis str. 168

68.085

87.037

0.593
  recA Riemerella anatipestifer ATCC 11845 = DSM 15868

62.315

89.153

0.556
  recA Acinetobacter baumannii D1279779

59.207

93.386

0.553
  recA Acinetobacter baylyi ADP1

59.714

92.593

0.553
  recA Neisseria gonorrhoeae MS11

60.35

90.741

0.548
  recA Neisseria gonorrhoeae MS11

60.35

90.741

0.548
  recA Neisseria gonorrhoeae strain FA1090

60.35

90.741

0.548
  recA Vibrio cholerae strain A1552

58.571

92.593

0.542
  recA Vibrio cholerae O1 biovar El Tor strain E7946

58.571

92.593

0.542
  recA Glaesserella parasuis strain SC1401

60

89.947

0.54
  recA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

62.848

85.45

0.537
  recA Pseudomonas stutzeri DSM 10701

57.184

92.063

0.526
  recA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

59.215

87.566

0.519
  recA Helicobacter pylori 26695

58.084

88.36

0.513
  recA Helicobacter pylori strain NCTC11637

58.084

88.36

0.513
  recA Ralstonia pseudosolanacearum GMI1000

58.133

87.831

0.511

Multiple sequence alignment