Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   ACLCDX_RS12040 Genome accession   NZ_CP180263
Coordinates   2370460..2370618 (-) Length   52 a.a.
NCBI ID   WP_415315998.1    Uniprot ID   -
Organism   Bacillus safensis strain BS22LVI     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2365460..2375618
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLCDX_RS12015 (ACLCDX_12015) rpsT 2365674..2365940 (+) 267 WP_024423042.1 30S ribosomal protein S20 -
  ACLCDX_RS12020 (ACLCDX_12020) holA 2366075..2367094 (-) 1020 WP_046311824.1 DNA polymerase III subunit delta -
  ACLCDX_RS12025 (ACLCDX_12025) - 2367331..2367465 (+) 135 WP_012010638.1 YqzM family protein -
  ACLCDX_RS12030 (ACLCDX_12030) - 2367505..2369832 (-) 2328 WP_197172735.1 DNA internalization-related competence protein ComEC/Rec2 -
  ACLCDX_RS12035 (ACLCDX_12035) - 2369825..2370394 (-) 570 WP_024423045.1 ComE operon protein 2 -
  ACLCDX_RS12040 (ACLCDX_12040) comEA 2370460..2370618 (-) 159 WP_415315998.1 ComEA family DNA-binding protein Machinery gene
  ACLCDX_RS12045 (ACLCDX_12045) - 2370597..2371088 (-) 492 WP_415315999.1 SLBB domain-containing protein -
  ACLCDX_RS12050 (ACLCDX_12050) comER 2371179..2372027 (+) 849 WP_024423047.1 late competence protein ComER -
  ACLCDX_RS12055 (ACLCDX_12055) - 2372076..2372819 (-) 744 WP_025092940.1 class I SAM-dependent DNA methyltransferase -
  ACLCDX_RS12060 (ACLCDX_12060) rsfS 2372816..2373172 (-) 357 WP_003217467.1 ribosome silencing factor -
  ACLCDX_RS12065 (ACLCDX_12065) yqeK 2373186..2373749 (-) 564 WP_024427944.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  ACLCDX_RS12070 (ACLCDX_12070) - 2373739..2374308 (-) 570 WP_087975783.1 nicotinate-nucleotide adenylyltransferase -
  ACLCDX_RS12075 (ACLCDX_12075) yhbY 2374322..2374612 (-) 291 WP_008342507.1 ribosome assembly RNA-binding protein YhbY -
  ACLCDX_RS12080 (ACLCDX_12080) aroE 2374606..2375448 (-) 843 WP_135032046.1 shikimate dehydrogenase -

Sequence

Protein


Download         Length: 52 a.a.        Molecular weight: 5889.68 Da        Isoelectric Point: 5.7578

>NTDB_id=1094980 ACLCDX_RS12040 WP_415315998.1 2370460..2370618(-) (comEA) [Bacillus safensis strain BS22LVI]
MQTINGIGPAKAEAIITYREEHGEFQQIEDLRNISGFGEKTIERLKSQLTVK

Nucleotide


Download         Length: 159 bp        

>NTDB_id=1094980 ACLCDX_RS12040 WP_415315998.1 2370460..2370618(-) (comEA) [Bacillus safensis strain BS22LVI]
TTGCAAACCATTAACGGCATAGGACCAGCTAAAGCCGAAGCTATCATTACGTATAGAGAGGAACACGGAGAATTTCAACA
AATTGAAGACTTGCGGAACATTTCAGGTTTTGGGGAAAAGACGATTGAACGGCTGAAAAGTCAATTGACCGTGAAGTAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(2-50)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Bacillus subtilis subsp. subtilis str. 168

61.538

100

0.615
  comEA Latilactobacillus sakei subsp. sakei 23K

60.784

98.077

0.596
  comEA Streptococcus thermophilus LMD-9

50.98

98.077

0.5
  comEA Lactococcus lactis subsp. cremoris KW2

47.059

98.077

0.462
  comEA Staphylococcus aureus N315

47.059

98.077

0.462
  comEA Staphylococcus aureus MW2

47.059

98.077

0.462
  Cj0011c Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

43.137

98.077

0.423
  comEA/celA/cilE Streptococcus mitis SK321

41.176

98.077

0.404
  comE Neisseria gonorrhoeae MS11

41.176

98.077

0.404
  comE Neisseria gonorrhoeae MS11

41.176

98.077

0.404
  comE Neisseria gonorrhoeae MS11

41.176

98.077

0.404
  comE Neisseria gonorrhoeae MS11

41.176

98.077

0.404
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

41.176

98.077

0.404
  comEA/celA/cilE Streptococcus pneumoniae R6

41.176

98.077

0.404
  comEA/celA/cilE Streptococcus pneumoniae Rx1

41.176

98.077

0.404
  comEA/celA/cilE Streptococcus mitis NCTC 12261

41.176

98.077

0.404
  comEA/celA/cilE Streptococcus pneumoniae D39

41.176

98.077

0.404
  comEA Acinetobacter baumannii D1279779

39.216

98.077

0.385
  comE1/comEA Haemophilus influenzae Rd KW20

46.512

82.692

0.385
  comA Synechocystis sp. PCC 6803

40

96.154

0.385
  comEA Vibrio cholerae strain A1552

51.282

75

0.385
  comEA Vibrio cholerae C6706

51.282

75

0.385
  comEA Vibrio parahaemolyticus RIMD 2210633

48.78

78.846

0.385
  comEA Acinetobacter baumannii strain A118

37.255

98.077

0.365
  comEA Acinetobacter baylyi ADP1

37.255

98.077

0.365
  comEA/comE1 Glaesserella parasuis strain SC1401

48.718

75

0.365

Multiple sequence alignment