Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS17504  |
| T6SS type | Type i3 |
| Strain | Serratia marcescens strain KZ11 |
| Replicon (RefSeq) | chromosome (NZ_PQGJ01000003) |
| Location | 455631..479047 |
| Function | - |
| Comment | Deletion of T6SS-1 genes had no effect on T6SS-mediated killing, indicating that T6SS-1 is not used to target?E. coli?or is not active under the tested conditions. |
| References | [1] Steele MI, Motta EVS, Gattu T, Martinez D, Moran NA. et al (2021) The Gut Microbiota Protects Bees from Invasion by a Bacterial Pathogen.. Microbiol Spectr. 9(2):e0039421. [PudMed:34523998] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | PAAR | TagB | TagC | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| C3R39_RS13275 | 451069..451539 | + | 471 | WP_103687199.1 | MarR family transcriptional regulator | ||
| C3R39_RS13280 | 451659..452291 | + | 633 | WP_033632650.1 | DNA-binding protein | ||
| C3R39_RS13285 | 452576..453538 | + | 963 | WP_103687200.1 | hypothetical protein | ||
| C3R39_RS13290 | 453586..454020 | - | 435 | WP_048324175.1 | DoxX family protein | ||
| T6CP259537 | TssA | C3R39_RS13295 | 455631..456596 | + | 966 | WP_004935378.1 | type VI secretion system ImpA family N-terminal domain-containing protein |
| T6CP259538 | TssB | C3R39_RS13300 (tssB) | 456621..457178 | + | 558 | WP_004935376.1 | type VI secretion system contractile sheath small subunit |
| T6CP259539 | TssC | C3R39_RS13305 (tssC) | 457175..458701 | + | 1527 | WP_004935371.1 | type VI secretion system contractile sheath large subunit |
| T6CP259540 | TssD | C3R39_RS13310 | 458933..459457 | + | 525 | WP_004935369.1 | Hcp family type VI secretion system effector |
| T6CP259541 | TssE | C3R39_RS13315 | 459539..459985 | + | 447 | WP_015378391.1 | GPW/gp25 family protein |
| T6CP259542 | TssF | C3R39_RS13320 (tssF) | 459997..461838 | + | 1842 | WP_004935363.1 | type VI secretion system baseplate subunit TssF |
| T6CP259543 | TssG | C3R39_RS13325 (tssG) | 461831..462859 | + | 1029 | WP_048324170.1 | type VI secretion system baseplate subunit TssG |
| T6CP259544 | TssH | C3R39_RS13330 (tssH) | 462876..465461 | + | 2586 | WP_103687201.1 | type VI secretion system ATPase TssH |
| T6CP259545 | TssI | C3R39_RS13335 (vgrG) | 465526..467787 | + | 2262 | WP_004935351.1 | type VI secretion system tip protein VgrG |
| C3R39_RS13340 | 467800..470025 | + | 2226 | WP_181008634.1 | DUF2169 domain-containing protein | ||
| T6CP259546 | TagB | C3R39_RS13345 | 470009..471169 | + | 1161 | WP_103687265.1 | pentapeptide repeat-containing protein |
| T6CP259547 | TagC | C3R39_RS13350 | 471162..471776 | + | 615 | WP_033632657.1 | DUF3540 domain-containing protein |
| T6CP259548 | PAAR | C3R39_RS13355 | 471783..472148 | + | 366 | WP_033632658.1 | DUF4150 domain-containing protein |
| T6CP259549 | TssJ | C3R39_RS13360 | 472158..472664 | + | 507 | WP_033632659.1 | type VI secretion lipoprotein TssJ |
| T6CP259550 | TssK | C3R39_RS13365 (tssK) | 472666..474024 | + | 1359 | WP_033632660.1 | type VI secretion system baseplate subunit TssK |
| T6CP259551 | TssL | C3R39_RS13370 (icmH) | 474021..475532 | + | 1512 | WP_021505815.1 | type IVB secretion system protein IcmH/DotU |
| T6CP259552 | TssM | C3R39_RS13375 (tssM) | 475568..479047 | + | 3480 | WP_103687203.1 | type VI secretion system membrane subunit TssM |
| C3R39_RS13380 | 479073..479426 | + | 354 | WP_033632662.1 | DUF6277 family protein | ||
| C3R39_RS13385 | 479693..479920 | - | 228 | WP_004935320.1 | hypothetical protein | ||
| C3R39_RS13390 | 480166..480456 | + | 291 | WP_004935318.1 | hypothetical protein | ||
| C3R39_RS13395 | 481161..481736 | + | 576 | WP_004935315.1 | LuxR family transcriptional regulator | ||
| C3R39_RS13400 | 481845..482714 | + | 870 | WP_103687204.1 | hypothetical protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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