Detailed information of T6SS

Note: only experimentally validated proteins are displayed in the graph.


Summary

T6SS ID T6SS01300 experimental
T6SS type Type i4b
Strain Burkholderia gladioli strain NGJ1
Replicon (GenBank) chromosome (LEKY01000012)
Location 91265..111362
Function anti-bacterial; anti-eukaryotic; effector translocation
Comment Burkholderia gladioli strain NGJ1 utilizes two different type VI secretion systems for antibacterial activity, and T6SS-1-strain was defective in Hcp-1 secretion but proficient in Hcp-2 secretion. On the other hand, T6SS-2-strain was defective in secretion of Hcp-2 but proficient in secretion of Hcp-1
References
[1] Yadav SK, Magotra A, Ghosh S, Krishnan A, Pradhan A, Kumar R, Das J, Sharma M, Jha G. et al (2021) Immunity proteins of dual nuclease T6SS effectors function as transcriptional repressors.. EMBO Rep. 22(6):e51857. [PudMed:33786997]
experimental Experimental investigation has been performed.

T6SS components and genome coordinates

ComponentTagFTagLTssATssBTssCTssDTssETssFTssGTssHTssJTssKTssLTssM
Number11111111111111


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Component ID
Component
Locus tag (Gene)
Coordinate
Strand
Size (bp)
NCBI ID
Product
T6CP016222TssLACI79_RS1391091265..92050-786503461798-
T6CP016223TssKACI79_RS1391592047..93393-1347836689638-
T6CP016224TssJACI79_RS1392093494..94111-618817530996-
T6CP016225TssBACI79_RS1393095172..95690+519503461802-
T6CP016226TssCACI79_RS1393595706..97196+1491503461803-
T6CP016227TssDACI79_RS1394097273..97776+504503461804-
T6CP016228TssEACI79_RS1394597865..98347+483503461805-
T6CP016229TssFACI79_RS1395098425..100263+1839836689640-
T6CP016230TssGACI79_RS13955100227..101324+1098516530522-
T6CP016231TssHACI79_RS13960101401..104076+2676836689641-
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flank Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files

    

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
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Regulator ID
Locus tag (Gene)
Regulator type
Regulatory pathway
Organism                
Replicon (Accession)
Coordinates (Strand)
NCBI ID
Target (Regulation)
No matching records found

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
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experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
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Immunity protein ID
Locus tag (Gene)
Cognate effector
Organism                
Replicon (Accession)
Coordinates (Strand)
NCBI ID
No matching records found

experimental Experimental investigation has been performed.
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Accessory protein ID
Locus tag (Gene)
Type            
Organism                
Replicon (Accession)
Coordinates (Strand)
NCBI ID
Related structure protein
Related effector
No matching records found