Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00381  |
| T6SS type | Type i1 |
| Strain | Xenorhabdus bovienii SS-2004 |
| Replicon (RefSeq) | chromosome (NC_013892) |
| Location | 268621..293062 |
| Function | anti-bacterial |
| Comment | The hcp1 mutant was unable to kill the prey on solid media, and this defect can be complemented by introducing hcp1 on a plasmid. T6SS-1 and T6SS-2 facilitated biofilm formation in XBJ. |
| References | [1] Kochanowsky RM, Bradshaw C, Forlastro I, Stock SP. et al (2020) Xenorhabdus bovienii strain jolietti uses a type 6 secretion system to kill closely related Xenorhabdus strains.. FEMS Microbiol Ecol. 96(8). [PudMed:32558899] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | FHA | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| XBJ1_RS01140 | 266234..267904 | - | 1671 | WP_012986872.1 | ShlB/FhaC/HecB family hemolysin secretion/activation protein | ||
| T6CP008854 | TssD | XBJ1_RS01145 | 268621..269139 | - | 519 | WP_012986874.1 | Hcp family type VI secretion system effector |
| T6CP003901 | TssB | XBJ1_RS01150 (tssB) | 270061..270558 | + | 498 | WP_012986876.1 | type VI secretion system contractile sheath small subunit |
| T6CP003902 | TssC | XBJ1_RS01155 (tssC) | 270579..272057 | + | 1479 | WP_012986877.1 | type VI secretion system contractile sheath large subunit |
| T6CP008855 | TssE | XBJ1_RS01160 (tssE) | 272060..272500 | + | 441 | WP_012986878.1 | type VI secretion system baseplate subunit TssE |
| T6CP003903 | TssF | XBJ1_RS01165 (tssF) | 272501..274333 | + | 1833 | WP_012986879.1 | type VI secretion system baseplate subunit TssF |
| T6CP003904 | TssG | XBJ1_RS01170 (tssG) | 274297..275349 | + | 1053 | WP_012986880.1 | type VI secretion system baseplate subunit TssG |
| T6CP011808 | FHA | XBJ1_RS01175 (tagH) | 275355..276650 | + | 1296 | WP_012986881.1 | type VI secretion system-associated FHA domain protein TagH |
| T6CP003905 | TssJ | XBJ1_RS01180 (tssJ) | 276634..277188 | + | 555 | WP_012986882.1 | type VI secretion system lipoprotein TssJ |
| T6CP003906 | TssK | XBJ1_RS01185 (tssK) | 277191..278543 | + | 1353 | WP_012986883.1 | type VI secretion system baseplate subunit TssK |
| T6CP003907 | TssL | XBJ1_RS01190 (icmH) | 278576..279313 | + | 738 | WP_173346404.1 | type IVB secretion system protein IcmH/DotU |
| T6CP003908 | TssH | XBJ1_RS01195 (tssH) | 279323..282037 | + | 2715 | WP_012986885.1 | type VI secretion system ATPase TssH |
| XBJ1_RS01200 | 282037..282831 | + | 795 | WP_012986886.1 | Fis family transcriptional regulator | ||
| XBJ1_RS01205 (tagO) | 282828..283493 | + | 666 | WP_012986887.1 | type VI secretion system-associated protein TagO | ||
| T6CP009380 | TssA | XBJ1_RS01210 (tssA) | 283499..284935 | + | 1437 | WP_012986888.1 | type VI secretion system protein TssA |
| T6CP003909 | TssM | XBJ1_RS01215 (tssM) | 284932..288501 | + | 3570 | WP_012986889.1 | type VI secretion system membrane subunit TssM |
| T6CP008856 | TssA | XBJ1_RS01220 | 288584..289975 | + | 1392 | WP_012986890.1 | type VI secretion system ImpA family N-terminal domain-containing protein |
| T6CP003910 | TssI | XBJ1_RS01225 (tssI) | 289991..293062 | + | 3072 | WP_012986891.1 | type VI secretion system tip protein VgrG |
| XBJ1_RS18935 | 293056..293421 | + | 366 | WP_012986892.1 | hypothetical protein | ||
| XBJ1_RS01240 | 293690..294145 | + | 456 | WP_012986893.1 | DUF1795 domain-containing protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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