Detailed information
Bioinformatically predicted
Overview
| Name | recA | Type | Machinery gene |
| Locus tag | WIS15_RS05545 | Genome accession | NZ_CP149762 |
| Coordinates | 1256726..1257772 (+) | Length | 348 a.a. |
| NCBI ID | WP_003428218.1 | Uniprot ID | A0A031WFI0 |
| Organism | Clostridioides difficile strain Z1322HCD0006 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1228354..1305566 | 1256726..1257772 | within | 0 |
Gene organization within MGE regions
Location: 1228354..1305566
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| WIS15_RS05430 (WIS15_05430) | acd | 1228429..1230252 (+) | 1824 | WP_003438294.1 | N-acetylglucosaminidase | - |
| WIS15_RS05435 (WIS15_05435) | - | 1230467..1234765 (+) | 4299 | WP_003438301.1 | PolC-type DNA polymerase III | - |
| WIS15_RS05440 (WIS15_05440) | rimP | 1234969..1235430 (+) | 462 | WP_003438303.1 | ribosome maturation factor RimP | - |
| WIS15_RS05445 (WIS15_05445) | nusA | 1235460..1236614 (+) | 1155 | WP_003428238.1 | transcription termination factor NusA | - |
| WIS15_RS05450 (WIS15_05450) | - | 1236621..1236902 (+) | 282 | WP_003419469.1 | YlxR family protein | - |
| WIS15_RS05455 (WIS15_05455) | - | 1236892..1237203 (+) | 312 | WP_003419470.1 | ribosomal L7Ae/L30e/S12e/Gadd45 family protein | - |
| WIS15_RS05460 (WIS15_05460) | infB | 1237225..1239165 (+) | 1941 | WP_003438306.1 | translation initiation factor IF-2 | - |
| WIS15_RS05465 (WIS15_05465) | rbfA | 1239208..1239588 (+) | 381 | WP_003428234.1 | 30S ribosome-binding factor RbfA | - |
| WIS15_RS05470 (WIS15_05470) | - | 1239569..1240552 (+) | 984 | WP_003438308.1 | bifunctional oligoribonuclease/PAP phosphatase NrnA | - |
| WIS15_RS05475 (WIS15_05475) | truB | 1240565..1241470 (+) | 906 | WP_003428232.1 | tRNA pseudouridine(55) synthase TruB | - |
| WIS15_RS05480 (WIS15_05480) | - | 1241601..1242530 (+) | 930 | WP_003438310.1 | bifunctional riboflavin kinase/FAD synthetase | - |
| WIS15_RS05485 (WIS15_05485) | rpsO | 1242634..1242891 (+) | 258 | WP_003419491.1 | 30S ribosomal protein S15 | - |
| WIS15_RS05490 (WIS15_05490) | - | 1243131..1243976 (+) | 846 | WP_009889099.1 | DegV family protein | - |
| WIS15_RS05495 (WIS15_05495) | pnp | 1244101..1246212 (+) | 2112 | WP_003438316.1 | polyribonucleotide nucleotidyltransferase | - |
| WIS15_RS05500 (WIS15_05500) | - | 1246478..1247221 (+) | 744 | WP_003438319.1 | polysaccharide deacetylase family protein | - |
| WIS15_RS05505 (WIS15_05505) | - | 1247379..1248626 (+) | 1248 | WP_003438321.1 | pitrilysin family protein | - |
| WIS15_RS05510 (WIS15_05510) | - | 1248661..1248906 (+) | 246 | WP_003419503.1 | YlmC/YmxH family sporulation protein | - |
| WIS15_RS05515 (WIS15_05515) | dapG | 1248916..1250139 (+) | 1224 | WP_003438324.1 | aspartate kinase | - |
| WIS15_RS05520 (WIS15_05520) | - | 1250252..1250986 (+) | 735 | WP_003428224.1 | ATP-dependent Clp protease proteolytic subunit | - |
| WIS15_RS05525 (WIS15_05525) | - | 1251109..1253520 (+) | 2412 | WP_003438328.1 | DNA translocase FtsK | - |
| WIS15_RS05530 (WIS15_05530) | mnmH | 1253523..1254581 (+) | 1059 | WP_003438330.1 | tRNA 2-selenouridine(34) synthase MnmH | - |
| WIS15_RS05535 (WIS15_05535) | rimO | 1254575..1255909 (+) | 1335 | WP_003438333.1 | 30S ribosomal protein S12 methylthiotransferase RimO | - |
| WIS15_RS05540 (WIS15_05540) | pgsA | 1255896..1256438 (+) | 543 | WP_021370268.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase | - |
| WIS15_RS05545 (WIS15_05545) | recA | 1256726..1257772 (+) | 1047 | WP_003428218.1 | recombinase RecA | Machinery gene |
| WIS15_RS05550 (WIS15_05550) | rny | 1257948..1259489 (+) | 1542 | WP_003428216.1 | ribonuclease Y | - |
| WIS15_RS05555 (WIS15_05555) | - | 1259803..1262139 (+) | 2337 | WP_003438341.1 | diguanylate cyclase | - |
| WIS15_RS05560 (WIS15_05560) | - | 1262521..1264302 (+) | 1782 | WP_003438344.1 | UvrD-helicase domain-containing protein | - |
| WIS15_RS05565 (WIS15_05565) | lepB | 1264384..1264914 (-) | 531 | WP_009902411.1 | signal peptidase I | - |
| WIS15_RS05570 (WIS15_05570) | - | 1264954..1265778 (-) | 825 | WP_003438350.1 | undecaprenyl-diphosphate phosphatase | - |
| WIS15_RS05575 (WIS15_05575) | - | 1266035..1266943 (+) | 909 | WP_009889110.1 | tyrosine-type recombinase/integrase | - |
| WIS15_RS05580 (WIS15_05580) | purB | 1267087..1268532 (+) | 1446 | WP_003438353.1 | adenylosuccinate lyase | - |
| WIS15_RS05585 (WIS15_05585) | - | 1268843..1269295 (+) | 453 | WP_003419561.1 | MarR family transcriptional regulator | - |
| WIS15_RS05590 (WIS15_05590) | - | 1269630..1270826 (-) | 1197 | WP_003438357.1 | pyridoxal phosphate-dependent aminotransferase | - |
| WIS15_RS05595 (WIS15_05595) | galT | 1271211..1272161 (+) | 951 | WP_003438360.1 | galactose-1-phosphate uridylyltransferase | - |
| WIS15_RS05600 (WIS15_05600) | - | 1272322..1273074 (+) | 753 | WP_003438367.1 | exodeoxyribonuclease III | - |
| WIS15_RS05605 (WIS15_05605) | - | 1273166..1273942 (-) | 777 | WP_003438370.1 | 3'-5' exonuclease | - |
| WIS15_RS05610 (WIS15_05610) | - | 1274257..1276155 (+) | 1899 | WP_003428202.1 | glutamine synthetase | - |
| WIS15_RS05615 (WIS15_05615) | - | 1276283..1277404 (-) | 1122 | WP_003438374.1 | glycosyltransferase | - |
| WIS15_RS05620 (WIS15_05620) | - | 1277603..1277935 (+) | 333 | WP_009889116.1 | PadR family transcriptional regulator | - |
| WIS15_RS05625 (WIS15_05625) | - | 1277922..1278980 (+) | 1059 | WP_003438377.1 | DUF1700 domain-containing protein | - |
| WIS15_RS05630 (WIS15_05630) | - | 1278973..1280043 (+) | 1071 | WP_003438380.1 | DUF4097 family beta strand repeat-containing protein | - |
| WIS15_RS05635 (WIS15_05635) | - | 1280145..1280681 (+) | 537 | WP_003428196.1 | lipoprotein | - |
| WIS15_RS05640 (WIS15_05640) | - | 1280797..1281504 (+) | 708 | WP_016729592.1 | lantibiotic protection ABC transporter ATP-binding protein | - |
| WIS15_RS05645 (WIS15_05645) | - | 1281506..1282222 (+) | 717 | WP_003438387.1 | lantibiotic immunity ABC transporter MutE/EpiE family permease subunit | - |
| WIS15_RS05650 (WIS15_05650) | - | 1282224..1282982 (+) | 759 | WP_021363441.1 | lantibiotic immunity ABC transporter MutG family permease subunit | - |
| WIS15_RS05655 (WIS15_05655) | - | 1283117..1284505 (+) | 1389 | WP_021368953.1 | two-component system sensor histidine kinase | - |
| WIS15_RS05660 (WIS15_05660) | - | 1284581..1285402 (-) | 822 | WP_003438396.1 | pyridoxamine kinase | - |
| WIS15_RS05665 (WIS15_05665) | - | 1285653..1286807 (+) | 1155 | WP_009902426.1 | amidase domain-containing protein | - |
| WIS15_RS05670 (WIS15_05670) | - | 1286990..1287190 (+) | 201 | WP_003419624.1 | cold-shock protein | - |
| WIS15_RS05675 (WIS15_05675) | - | 1287611..1288039 (+) | 429 | WP_009889129.1 | CBS domain-containing protein | - |
| WIS15_RS05680 (WIS15_05680) | - | 1288182..1288937 (-) | 756 | WP_009889131.1 | peptidylprolyl isomerase | - |
| WIS15_RS05685 (WIS15_05685) | - | 1289638..1290144 (-) | 507 | WP_003428186.1 | hypothetical protein | - |
| WIS15_RS05690 (WIS15_05690) | - | 1290226..1290546 (-) | 321 | WP_003428185.1 | XRE family transcriptional regulator | - |
| WIS15_RS05695 (WIS15_05695) | - | 1290715..1290912 (+) | 198 | WP_003419641.1 | helix-turn-helix transcriptional regulator | - |
| WIS15_RS05700 (WIS15_05700) | - | 1291017..1291457 (+) | 441 | WP_003428183.1 | hypothetical protein | - |
| WIS15_RS05705 (WIS15_05705) | - | 1291706..1292149 (+) | 444 | WP_003438413.1 | DUF6838 family protein | - |
| WIS15_RS05710 (WIS15_05710) | - | 1292154..1293218 (+) | 1065 | WP_003438414.1 | phage tail sheath subtilisin-like domain-containing protein | - |
| WIS15_RS05715 (WIS15_05715) | - | 1293232..1293660 (+) | 429 | WP_003419646.1 | phage tail tube protein | - |
| WIS15_RS05720 (WIS15_05720) | - | 1293774..1294220 (+) | 447 | WP_003419647.1 | phage portal protein | - |
| WIS15_RS05725 (WIS15_05725) | - | 1294247..1294414 (+) | 168 | WP_003419648.1 | hypothetical protein | - |
| WIS15_RS05730 (WIS15_05730) | - | 1294414..1296867 (+) | 2454 | WP_003438437.1 | hypothetical protein | - |
| WIS15_RS05735 (WIS15_05735) | - | 1296867..1297289 (+) | 423 | WP_003428168.1 | phage baseplate protein | - |
| WIS15_RS05740 (WIS15_05740) | - | 1297571..1299100 (+) | 1530 | WP_003438440.1 | NlpC/P60 family protein | - |
| WIS15_RS05745 (WIS15_05745) | - | 1299116..1299442 (+) | 327 | WP_003438447.1 | DUF2577 domain-containing protein | - |
| WIS15_RS05750 (WIS15_05750) | - | 1299442..1299870 (+) | 429 | WP_003438449.1 | DUF2634 domain-containing protein | - |
| WIS15_RS05755 (WIS15_05755) | - | 1299863..1300915 (+) | 1053 | WP_003438450.1 | baseplate J/gp47 family protein | - |
| WIS15_RS05760 (WIS15_05760) | - | 1300912..1301610 (+) | 699 | WP_003438451.1 | putative phage tail protein | - |
| WIS15_RS05765 (WIS15_05765) | - | 1301611..1302594 (+) | 984 | WP_003438452.1 | phage tail protein | - |
Sequence
Protein
Download Length: 348 a.a. Molecular weight: 37377.68 Da Isoelectric Point: 4.8236
>NTDB_id=961289 WIS15_RS05545 WP_003428218.1 1256726..1257772(+) (recA) [Clostridioides difficile strain Z1322HCD0006]
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEI
DEKVRAFYNLNEEHEESGTSVSKEIVEE
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEI
DEKVRAFYNLNEEHEESGTSVSKEIVEE
Nucleotide
Download Length: 1047 bp
>NTDB_id=961289 WIS15_RS05545 WP_003428218.1 1256726..1257772(+) (recA) [Clostridioides difficile strain Z1322HCD0006]
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGACATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAGACTACTGTTGCGCTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATATGCAAAAGC
TTTGGGTGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGATTCTCATGTAGGTTTACAAGCTAGACTTATGTCACAAGCACTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCAGAAACTACTACTGGAGGAC
GTGCACTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGATACAATAAAACAAGGTGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTTGTTAAAAACAAAGTAGCACCACCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGGATTTCAAAAATTGGAGACCTTTTAGATATAGCTGCTGATGTAGATATAGTTAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAAGATAATTTAGATTTAACTACTGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAATCAGGTACTTCAGTATCAAAAGAAATTGTAGA
AGAATAA
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGACATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAGACTACTGTTGCGCTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATATGCAAAAGC
TTTGGGTGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGATTCTCATGTAGGTTTACAAGCTAGACTTATGTCACAAGCACTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCAGAAACTACTACTGGAGGAC
GTGCACTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGATACAATAAAACAAGGTGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTTGTTAAAAACAAAGTAGCACCACCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGGATTTCAAAAATTGGAGACCTTTTAGATATAGCTGCTGATGTAGATATAGTTAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAAGATAATTTAGATTTAACTACTGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAATCAGGTACTTCAGTATCAAAAGAAATTGTAGA
AGAATAA
Similar proteins
Only experimentally validated proteins are listed.