Detailed information
Bioinformatically predicted
Overview
| Name | recA | Type | Machinery gene |
| Locus tag | cd221108_RS06450 | Genome accession | NZ_CP144679 |
| Coordinates | 1371671..1372717 (+) | Length | 348 a.a. |
| NCBI ID | WP_021364420.1 | Uniprot ID | A0A9X8RFQ1 |
| Organism | Clostridioides difficile strain cd221108_barcode08 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1345624..1410456 | 1371671..1372717 | within | 0 |
Gene organization within MGE regions
Location: 1345624..1410456
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| cd221108_RS06335 (cd221108_1268) | rimP | 1348040..1348501 (+) | 462 | WP_003438303.1 | ribosome maturation factor RimP | - |
| cd221108_RS06340 (cd221108_1269) | nusA | 1348531..1349685 (+) | 1155 | WP_003428238.1 | transcription termination factor NusA | - |
| cd221108_RS06345 (cd221108_1270) | - | 1349692..1349973 (+) | 282 | WP_003419469.1 | YlxR family protein | - |
| cd221108_RS06350 (cd221108_1271) | - | 1349963..1350274 (+) | 312 | WP_003419470.1 | ribosomal L7Ae/L30e/S12e/Gadd45 family protein | - |
| cd221108_RS06355 (cd221108_1272) | infB | 1350296..1352236 (+) | 1941 | WP_003438306.1 | translation initiation factor IF-2 | - |
| cd221108_RS06360 (cd221108_1273) | rbfA | 1352279..1352659 (+) | 381 | WP_003428234.1 | 30S ribosome-binding factor RbfA | - |
| cd221108_RS06365 | - | 1352640..1353317 (+) | 678 | Protein_1162 | DHH family phosphoesterase | - |
| cd221108_RS06370 (cd221108_1275) | tnpB | 1353957..1355075 (+) | 1119 | WP_032548186.1 | IS200/IS605 family element RNA-guided endonuclease TnpB | - |
| cd221108_RS06375 | - | 1355193..1355498 (+) | 306 | Protein_1164 | DHHA1 domain-containing protein | - |
| cd221108_RS06380 (cd221108_1277) | truB | 1355511..1356416 (+) | 906 | WP_003428232.1 | tRNA pseudouridine(55) synthase TruB | - |
| cd221108_RS06385 (cd221108_1278) | - | 1356547..1357476 (+) | 930 | WP_003438310.1 | bifunctional riboflavin kinase/FAD synthetase | - |
| cd221108_RS06390 (cd221108_1279) | rpsO | 1357580..1357837 (+) | 258 | WP_003419491.1 | 30S ribosomal protein S15 | - |
| cd221108_RS06395 (cd221108_1280) | - | 1358077..1358922 (+) | 846 | WP_009889099.1 | DegV family protein | - |
| cd221108_RS06400 (cd221108_1281) | pnp | 1359047..1361158 (+) | 2112 | WP_003438316.1 | polyribonucleotide nucleotidyltransferase | - |
| cd221108_RS06405 (cd221108_1282) | - | 1361424..1362167 (+) | 744 | WP_003438319.1 | polysaccharide deacetylase family protein | - |
| cd221108_RS06410 (cd221108_1283) | - | 1362325..1363572 (+) | 1248 | WP_009902409.1 | pitrilysin family protein | - |
| cd221108_RS06415 (cd221108_1284) | - | 1363607..1363852 (+) | 246 | WP_021364423.1 | YlmC/YmxH family sporulation protein | - |
| cd221108_RS06420 (cd221108_1285) | dapG | 1363862..1365085 (+) | 1224 | WP_003438324.1 | aspartate kinase | - |
| cd221108_RS06425 (cd221108_1286) | - | 1365198..1365931 (+) | 734 | Protein_1174 | ATP-dependent Clp protease proteolytic subunit | - |
| cd221108_RS06430 (cd221108_1288) | - | 1366054..1368465 (+) | 2412 | WP_003438328.1 | DNA translocase FtsK | - |
| cd221108_RS06435 (cd221108_1289) | mnmH | 1368468..1369526 (+) | 1059 | WP_003433322.1 | tRNA 2-selenouridine(34) synthase MnmH | - |
| cd221108_RS06440 (cd221108_1290) | rimO | 1369520..1370854 (+) | 1335 | WP_003433320.1 | 30S ribosomal protein S12 methylthiotransferase RimO | - |
| cd221108_RS06445 (cd221108_1291) | pgsA | 1370841..1371383 (+) | 543 | WP_009889106.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase | - |
| cd221108_RS06450 (cd221108_1292) | recA | 1371671..1372717 (+) | 1047 | WP_021364420.1 | recombinase RecA | Machinery gene |
| cd221108_RS06455 (cd221108_1293) | rny | 1372893..1374434 (+) | 1542 | WP_003428216.1 | ribonuclease Y | - |
| cd221108_RS06460 (cd221108_1294) | - | 1375069..1376850 (+) | 1782 | WP_003438344.1 | UvrD-helicase domain-containing protein | - |
| cd221108_RS06465 (cd221108_1295) | lepB | 1376932..1377462 (-) | 531 | WP_009902411.1 | signal peptidase I | - |
| cd221108_RS06470 (cd221108_1296) | - | 1377502..1378326 (-) | 825 | WP_003438350.1 | undecaprenyl-diphosphate phosphatase | - |
| cd221108_RS06475 (cd221108_1297) | - | 1378583..1379491 (+) | 909 | WP_009889110.1 | tyrosine-type recombinase/integrase | - |
| cd221108_RS06480 (cd221108_1298) | purB | 1379635..1381080 (+) | 1446 | WP_003438353.1 | adenylosuccinate lyase | - |
| cd221108_RS06485 (cd221108_1299) | - | 1381391..1381843 (+) | 453 | WP_003419561.1 | MarR family transcriptional regulator | - |
| cd221108_RS06490 (cd221108_1300) | - | 1382255..1383832 (+) | 1578 | WP_021364419.1 | PTS transporter subunit EIIC | - |
| cd221108_RS06495 (cd221108_1301) | - | 1383980..1384732 (+) | 753 | WP_009892977.1 | MurR/RpiR family transcriptional regulator | - |
| cd221108_RS06500 (cd221108_1302) | - | 1384865..1386211 (+) | 1347 | WP_009902417.1 | 6-phospho-alpha-glucosidase | - |
| cd221108_RS06505 (cd221108_1304) | - | 1386323..1387518 (-) | 1196 | Protein_1190 | pyridoxal phosphate-dependent aminotransferase | - |
| cd221108_RS06510 (cd221108_1305) | galT | 1387903..1388853 (+) | 951 | WP_009889113.1 | galactose-1-phosphate uridylyltransferase | - |
| cd221108_RS06515 (cd221108_1306) | - | 1389014..1389766 (+) | 753 | WP_003438367.1 | exodeoxyribonuclease III | - |
| cd221108_RS06520 (cd221108_1307) | - | 1389858..1390634 (-) | 777 | WP_009896237.1 | 3'-5' exonuclease | - |
| cd221108_RS06525 (cd221108_1308) | - | 1390949..1392847 (+) | 1899 | WP_003428202.1 | glutamine synthetase | - |
| cd221108_RS06530 (cd221108_1309) | - | 1392975..1394096 (-) | 1122 | WP_003438374.1 | glycosyltransferase | - |
| cd221108_RS06535 (cd221108_1310) | - | 1394295..1394627 (+) | 333 | WP_009889116.1 | PadR family transcriptional regulator | - |
| cd221108_RS06540 (cd221108_1311) | - | 1394614..1395672 (+) | 1059 | WP_021367719.1 | DUF1700 domain-containing protein | - |
| cd221108_RS06545 (cd221108_1312) | - | 1395665..1396735 (+) | 1071 | WP_021364425.1 | DUF4097 family beta strand repeat-containing protein | - |
| cd221108_RS06550 (cd221108_1313) | - | 1396837..1397373 (+) | 537 | WP_003428196.1 | lipoprotein | - |
| cd221108_RS06555 (cd221108_1314) | - | 1397489..1398196 (+) | 708 | WP_009902422.1 | lantibiotic protection ABC transporter ATP-binding protein | - |
| cd221108_RS06560 (cd221108_1315) | - | 1398198..1398914 (+) | 717 | WP_009896246.1 | lantibiotic immunity ABC transporter MutE/EpiE family permease subunit | - |
| cd221108_RS06565 (cd221108_1316) | - | 1398916..1399674 (+) | 759 | WP_009902423.1 | lantibiotic immunity ABC transporter MutG family permease subunit | - |
| cd221108_RS06570 (cd221108_1317) | - | 1399809..1401197 (+) | 1389 | WP_021364432.1 | two-component system sensor histidine kinase | - |
| cd221108_RS06575 (cd221108_1318) | - | 1401273..1402094 (-) | 822 | WP_021364435.1 | pyridoxamine kinase | - |
| cd221108_RS06580 (cd221108_1319) | - | 1402345..1403499 (+) | 1155 | WP_009902426.1 | amidase domain-containing protein | - |
| cd221108_RS06585 (cd221108_1320) | - | 1403682..1403882 (+) | 201 | WP_003419624.1 | cold-shock protein | - |
| cd221108_RS06590 (cd221108_1321) | - | 1404303..1404731 (+) | 429 | WP_009889129.1 | CBS domain-containing protein | - |
| cd221108_RS06595 (cd221108_1322) | - | 1404874..1405629 (-) | 756 | WP_009889131.1 | peptidylprolyl isomerase | - |
| cd221108_RS06600 (cd221108_1324) | - | 1406330..1406836 (-) | 507 | WP_003428186.1 | hypothetical protein | - |
| cd221108_RS06605 (cd221108_1325) | - | 1406918..1407238 (-) | 321 | WP_003428185.1 | XRE family transcriptional regulator | - |
| cd221108_RS06610 (cd221108_1326) | - | 1407407..1407604 (+) | 198 | WP_003419641.1 | helix-turn-helix transcriptional regulator | - |
| cd221108_RS06615 (cd221108_1327) | - | 1407709..1408149 (+) | 441 | WP_003428183.1 | hypothetical protein | - |
| cd221108_RS06620 (cd221108_1328) | - | 1408398..1408841 (+) | 444 | WP_003438413.1 | DUF6838 family protein | - |
| cd221108_RS06625 (cd221108_1329) | - | 1408846..1409910 (+) | 1065 | WP_003438414.1 | phage tail sheath subtilisin-like domain-containing protein | - |
| cd221108_RS06630 (cd221108_1330) | - | 1409924..1410352 (+) | 429 | WP_003419646.1 | phage tail tube protein | - |
Sequence
Protein
Download Length: 348 a.a. Molecular weight: 37389.74 Da Isoelectric Point: 4.8236
>NTDB_id=934364 cd221108_RS06450 WP_021364420.1 1371671..1372717(+) (recA) [Clostridioides difficile strain cd221108_barcode08]
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEI
DEKVRAFYNLNEEHEESGISVSKEIVEE
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEI
DEKVRAFYNLNEEHEESGISVSKEIVEE
Nucleotide
Download Length: 1047 bp
>NTDB_id=934364 cd221108_RS06450 WP_021364420.1 1371671..1372717(+) (recA) [Clostridioides difficile strain cd221108_barcode08]
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGACATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAAACTACTGTTGCGCTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATATGCAAAAGC
TTTGGGTGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGATTCTCATGTAGGTTTACAAGCTAGACTTATGTCACAAGCACTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCGGAAACTACTACTGGAGGAC
GTGCACTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGATACAATAAAACAAGGTGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTTGTTAAAAACAAAGTAGCACCACCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGAATTTCAAAAATTGGAGACCTTTTAGATATAGCTGCTGATGTAGATATAGTTAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAAGATAATTTAGATTTAACTACTGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAATCAGGTATTTCAGTATCAAAAGAAATTGTAGA
AGAATAA
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGACATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAAACTACTGTTGCGCTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATATGCAAAAGC
TTTGGGTGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGATTCTCATGTAGGTTTACAAGCTAGACTTATGTCACAAGCACTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCGGAAACTACTACTGGAGGAC
GTGCACTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGATACAATAAAACAAGGTGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTTGTTAAAAACAAAGTAGCACCACCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGAATTTCAAAAATTGGAGACCTTTTAGATATAGCTGCTGATGTAGATATAGTTAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAAGATAATTTAGATTTAACTACTGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAATCAGGTATTTCAGTATCAAAAGAAATTGTAGA
AGAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.