Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AB6N08_RS05495 Genome accession   NZ_CP163448
Coordinates   1067880..1068536 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli O102:H6 strain M2021_10044824_1_E     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1062880..1073536
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB6N08_RS05465 (AB6N08_05470) yecA 1064131..1064796 (-) 666 WP_000847881.1 UPF0149 family protein YecA -
  AB6N08_RS05485 (AB6N08_05490) pgsA 1065446..1065994 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AB6N08_RS05490 (AB6N08_05495) uvrC 1066051..1067883 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  AB6N08_RS05495 (AB6N08_05500) letA 1067880..1068536 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  AB6N08_RS05500 (AB6N08_05505) yecU 1068832..1069008 (+) 177 WP_000590347.1 protein YecU -
  AB6N08_RS05505 (AB6N08_05510) yecF 1068995..1069219 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  AB6N08_RS05510 (AB6N08_05515) sdiA 1069286..1070008 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  AB6N08_RS05515 (AB6N08_05520) tcyN 1070238..1070990 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  AB6N08_RS05520 (AB6N08_05525) tcyL 1070987..1071655 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  AB6N08_RS05525 (AB6N08_05530) dcyD 1071670..1072656 (-) 987 WP_020232905.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=925904 AB6N08_RS05495 WP_000611328.1 1067880..1068536(-) (letA) [Escherichia coli O102:H6 strain M2021_10044824_1_E]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=925904 AB6N08_RS05495 WP_000611328.1 1067880..1068536(-) (letA) [Escherichia coli O102:H6 strain M2021_10044824_1_E]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482