Detailed information
Bioinformatically predicted
Overview
| Name | recA | Type | Machinery gene |
| Locus tag | ITI90_RS06740 | Genome accession | NZ_CP126067 |
| Coordinates | 1410661..1411707 (+) | Length | 348 a.a. |
| NCBI ID | WP_021364420.1 | Uniprot ID | A0A9X8RFQ1 |
| Organism | Clostridioides difficile strain CDI-30 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1384613..1449447 | 1410661..1411707 | within | 0 |
Gene organization within MGE regions
Location: 1384613..1449447
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ITI90_RS06625 (ITI90_06625) | rimP | 1387029..1387490 (+) | 462 | WP_003438303.1 | ribosome maturation factor RimP | - |
| ITI90_RS06630 (ITI90_06630) | nusA | 1387520..1388674 (+) | 1155 | WP_003428238.1 | transcription termination factor NusA | - |
| ITI90_RS06635 (ITI90_06635) | rnpM | 1388681..1388962 (+) | 282 | WP_003419469.1 | RNase P modulator RnpM | - |
| ITI90_RS06640 (ITI90_06640) | - | 1388952..1389263 (+) | 312 | WP_003419470.1 | L7Ae/L30e/S12e/Gadd45 family ribosomal protein | - |
| ITI90_RS06645 (ITI90_06645) | infB | 1389285..1391225 (+) | 1941 | WP_003438306.1 | translation initiation factor IF-2 | - |
| ITI90_RS06650 (ITI90_06650) | rbfA | 1391268..1391648 (+) | 381 | WP_003428234.1 | 30S ribosome-binding factor RbfA | - |
| ITI90_RS06655 (ITI90_06655) | - | 1391629..1392306 (+) | 678 | Protein_1223 | DHH family phosphoesterase | - |
| ITI90_RS06660 (ITI90_06660) | tnpB | 1392946..1394064 (+) | 1119 | WP_032548186.1 | IS200/IS605 family element RNA-guided endonuclease TnpB | - |
| ITI90_RS06665 (ITI90_06665) | - | 1394182..1394487 (+) | 306 | Protein_1225 | DHH family phosphoesterase | - |
| ITI90_RS06670 (ITI90_06670) | truB | 1394500..1395405 (+) | 906 | WP_003428232.1 | tRNA pseudouridine(55) synthase TruB | - |
| ITI90_RS06675 (ITI90_06675) | - | 1395536..1396465 (+) | 930 | WP_003438310.1 | bifunctional riboflavin kinase/FAD synthetase | - |
| ITI90_RS06680 (ITI90_06680) | rpsO | 1396569..1396826 (+) | 258 | WP_003419491.1 | 30S ribosomal protein S15 | - |
| ITI90_RS06685 (ITI90_06685) | - | 1397066..1397911 (+) | 846 | WP_009889099.1 | DegV family protein | - |
| ITI90_RS06690 (ITI90_06690) | pnp | 1398036..1400147 (+) | 2112 | WP_003438316.1 | polyribonucleotide nucleotidyltransferase | - |
| ITI90_RS06695 (ITI90_06695) | - | 1400413..1401156 (+) | 744 | WP_003438319.1 | polysaccharide deacetylase family protein | - |
| ITI90_RS06700 (ITI90_06700) | - | 1401314..1402561 (+) | 1248 | WP_009902409.1 | M16 family metallopeptidase | - |
| ITI90_RS06705 (ITI90_06705) | - | 1402596..1402841 (+) | 246 | WP_021364423.1 | YlmC/YmxH family sporulation protein | - |
| ITI90_RS06710 (ITI90_06710) | dapG | 1402851..1404074 (+) | 1224 | WP_003438324.1 | aspartate kinase | - |
| ITI90_RS06715 (ITI90_06715) | - | 1404187..1404921 (+) | 735 | WP_021364422.1 | ClpP family protease | - |
| ITI90_RS06720 (ITI90_06720) | - | 1405044..1407455 (+) | 2412 | WP_003438328.1 | FtsK/SpoIIIE family DNA translocase | - |
| ITI90_RS06725 (ITI90_06725) | mnmH | 1407458..1408516 (+) | 1059 | WP_003433322.1 | tRNA 2-selenouridine(34) synthase MnmH | - |
| ITI90_RS06730 (ITI90_06730) | rimO | 1408510..1409844 (+) | 1335 | WP_003433320.1 | 30S ribosomal protein S12 methylthiotransferase RimO | - |
| ITI90_RS06735 (ITI90_06735) | pgsA | 1409831..1410373 (+) | 543 | WP_009889106.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase | - |
| ITI90_RS06740 (ITI90_06740) | recA | 1410661..1411707 (+) | 1047 | WP_021364420.1 | recombinase RecA | Machinery gene |
| ITI90_RS06745 (ITI90_06745) | rny | 1411883..1413424 (+) | 1542 | WP_003428216.1 | ribonuclease Y | - |
| ITI90_RS06750 (ITI90_06750) | - | 1414059..1415840 (+) | 1782 | WP_003438344.1 | UvrD-helicase domain-containing protein | - |
| ITI90_RS06755 (ITI90_06755) | lepB | 1415922..1416452 (-) | 531 | WP_009902411.1 | signal peptidase I | - |
| ITI90_RS06760 (ITI90_06760) | - | 1416492..1417316 (-) | 825 | WP_003438350.1 | undecaprenyl-diphosphate phosphatase | - |
| ITI90_RS06765 (ITI90_06765) | - | 1417573..1418481 (+) | 909 | WP_009889110.1 | tyrosine-type recombinase/integrase | - |
| ITI90_RS06770 (ITI90_06770) | purB | 1418625..1420070 (+) | 1446 | WP_003438353.1 | adenylosuccinate lyase | - |
| ITI90_RS06775 (ITI90_06775) | - | 1420381..1420833 (+) | 453 | WP_003419561.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
| ITI90_RS06780 (ITI90_06780) | - | 1421245..1422822 (+) | 1578 | WP_021364419.1 | PTS transporter subunit EIIC | - |
| ITI90_RS06785 (ITI90_06785) | - | 1422970..1423722 (+) | 753 | WP_009892977.1 | MurR/RpiR family transcriptional regulator | - |
| ITI90_RS06790 (ITI90_06790) | - | 1423855..1425201 (+) | 1347 | WP_009902417.1 | 6-phospho-alpha-glucosidase | - |
| ITI90_RS06795 (ITI90_06795) | - | 1425313..1426509 (-) | 1197 | WP_003438357.1 | pyridoxal phosphate-dependent aminotransferase | - |
| ITI90_RS06800 (ITI90_06800) | galT | 1426894..1427844 (+) | 951 | WP_009889113.1 | galactose-1-phosphate uridylyltransferase | - |
| ITI90_RS06805 (ITI90_06805) | - | 1428005..1428757 (+) | 753 | WP_003438367.1 | exodeoxyribonuclease III | - |
| ITI90_RS06810 (ITI90_06810) | - | 1428849..1429625 (-) | 777 | WP_009896237.1 | 3'-5' exonuclease | - |
| ITI90_RS06815 (ITI90_06815) | - | 1429940..1431838 (+) | 1899 | WP_003428202.1 | glutamine synthetase | - |
| ITI90_RS06820 (ITI90_06820) | - | 1431966..1433087 (-) | 1122 | WP_003438374.1 | MGDG synthase family glycosyltransferase | - |
| ITI90_RS06825 (ITI90_06825) | - | 1433286..1433618 (+) | 333 | WP_009889116.1 | PadR family transcriptional regulator | - |
| ITI90_RS06830 (ITI90_06830) | - | 1433605..1434663 (+) | 1059 | WP_021367719.1 | DUF1700 domain-containing protein | - |
| ITI90_RS06835 (ITI90_06835) | - | 1434656..1435726 (+) | 1071 | WP_021364425.1 | DUF4097 family beta strand repeat-containing protein | - |
| ITI90_RS06840 (ITI90_06840) | - | 1435828..1436364 (+) | 537 | WP_003428196.1 | lipoprotein | - |
| ITI90_RS06845 (ITI90_06845) | - | 1436480..1437187 (+) | 708 | WP_009902422.1 | lantibiotic protection ABC transporter ATP-binding protein | - |
| ITI90_RS06850 (ITI90_06850) | - | 1437189..1437905 (+) | 717 | WP_009896246.1 | lantibiotic immunity ABC transporter MutE/EpiE family permease subunit | - |
| ITI90_RS06855 (ITI90_06855) | - | 1437907..1438665 (+) | 759 | WP_009902423.1 | lantibiotic immunity ABC transporter MutG family permease subunit | - |
| ITI90_RS06860 (ITI90_06860) | - | 1438800..1440188 (+) | 1389 | WP_021364432.1 | two-component system sensor histidine kinase | - |
| ITI90_RS06865 (ITI90_06865) | - | 1440264..1441085 (-) | 822 | WP_021364435.1 | pyridoxamine kinase | - |
| ITI90_RS06870 (ITI90_06870) | - | 1441336..1442490 (+) | 1155 | WP_009902426.1 | amidase domain-containing protein | - |
| ITI90_RS06875 (ITI90_06875) | - | 1442673..1442873 (+) | 201 | WP_003419624.1 | cold-shock protein | - |
| ITI90_RS06880 (ITI90_06880) | - | 1443294..1443722 (+) | 429 | WP_009889129.1 | CBS domain-containing protein | - |
| ITI90_RS06885 (ITI90_06885) | - | 1443865..1444620 (-) | 756 | WP_009889131.1 | peptidylprolyl isomerase | - |
| ITI90_RS06890 (ITI90_06890) | - | 1445321..1445827 (-) | 507 | WP_003428186.1 | ImmA/IrrE family metallo-endopeptidase | - |
| ITI90_RS06895 (ITI90_06895) | - | 1445909..1446229 (-) | 321 | WP_003428185.1 | XRE family transcriptional regulator | - |
| ITI90_RS06900 (ITI90_06900) | - | 1446398..1446595 (+) | 198 | WP_003419641.1 | helix-turn-helix transcriptional regulator | - |
| ITI90_RS06905 (ITI90_06905) | - | 1446700..1447140 (+) | 441 | WP_003428183.1 | hypothetical protein | - |
| ITI90_RS06910 (ITI90_06910) | - | 1447389..1447832 (+) | 444 | WP_003438413.1 | phage tail terminator family protein | - |
| ITI90_RS06915 (ITI90_06915) | - | 1447837..1448901 (+) | 1065 | WP_003438414.1 | phage tail sheath subtilisin-like domain-containing protein | - |
| ITI90_RS06920 (ITI90_06920) | - | 1448915..1449343 (+) | 429 | WP_003419646.1 | phage tail tube protein | - |
Sequence
Protein
Download Length: 348 a.a. Molecular weight: 37389.74 Da Isoelectric Point: 4.8236
>NTDB_id=834470 ITI90_RS06740 WP_021364420.1 1410661..1411707(+) (recA) [Clostridioides difficile strain CDI-30]
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEI
DEKVRAFYNLNEEHEESGISVSKEIVEE
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEI
DEKVRAFYNLNEEHEESGISVSKEIVEE
Nucleotide
Download Length: 1047 bp
>NTDB_id=834470 ITI90_RS06740 WP_021364420.1 1410661..1411707(+) (recA) [Clostridioides difficile strain CDI-30]
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGACATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAAACTACTGTTGCGCTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATATGCAAAAGC
TTTGGGTGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGATTCTCATGTAGGTTTACAAGCTAGACTTATGTCACAAGCACTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCGGAAACTACTACTGGAGGAC
GTGCACTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGATACAATAAAACAAGGTGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTTGTTAAAAACAAAGTAGCACCACCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGAATTTCAAAAATTGGAGACCTTTTAGATATAGCTGCTGATGTAGATATAGTTAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAAGATAATTTAGATTTAACTACTGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAATCAGGTATTTCAGTATCAAAAGAAATTGTAGA
AGAATAA
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGACATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAAACTACTGTTGCGCTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATATGCAAAAGC
TTTGGGTGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGATTCTCATGTAGGTTTACAAGCTAGACTTATGTCACAAGCACTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCGGAAACTACTACTGGAGGAC
GTGCACTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGATACAATAAAACAAGGTGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTTGTTAAAAACAAAGTAGCACCACCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGAATTTCAAAAATTGGAGACCTTTTAGATATAGCTGCTGATGTAGATATAGTTAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAAGATAATTTAGATTTAACTACTGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAATCAGGTATTTCAGTATCAAAAGAAATTGTAGA
AGAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.