Detailed information    

insolico Bioinformatically predicted

Overview

Name   recA   Type   Machinery gene
Locus tag   H7674_RS08535 Genome accession   NZ_AP023388
Coordinates   1755834..1756970 (-) Length   378 a.a.
NCBI ID   WP_011285265.1    Uniprot ID   Q48QW7
Organism   Streptococcus pyogenes strain NIH35     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1750834..1761970
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7674_RS08510 (SPNIH35_16320) - 1752056..1753615 (-) 1560 WP_011285264.1 membrane protein -
  H7674_RS08515 (SPNIH35_16330) - 1754029..1754334 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  H7674_RS08520 (SPNIH35_16340) ruvX 1754346..1754765 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  H7674_RS08525 (SPNIH35_16350) - 1754762..1755031 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  H7674_RS08530 (SPNIH35_16360) spx 1755145..1755543 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  H7674_RS08535 (SPNIH35_16370) recA 1755834..1756970 (-) 1137 WP_011285265.1 recombinase RecA Machinery gene
  H7674_RS08540 (SPNIH35_16380) cinA 1757059..1758330 (-) 1272 WP_011285266.1 competence/damage-inducible protein A Machinery gene
  H7674_RS08545 (SPNIH35_16390) - 1758399..1758959 (-) 561 WP_011018314.1 DNA-3-methyladenine glycosylase I -
  H7674_RS08550 (SPNIH35_16400) ruvA 1758969..1759565 (-) 597 WP_011285268.1 Holliday junction branch migration protein RuvA -
  H7674_RS08555 (SPNIH35_16410) - 1759567..1760787 (-) 1221 WP_011285269.1 MDR family MFS transporter -

Sequence

Protein


Download         Length: 378 a.a.        Molecular weight: 40672.32 Da        Isoelectric Point: 4.8451

>NTDB_id=82756 H7674_RS08535 WP_011285265.1 1755834..1756970(-) (recA) [Streptococcus pyogenes strain NIH35]
MAKKLKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGERAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGP
ESSGKTTVALHAVAQAQKEGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGNPETTPGGRALKFYASVRLDVRG
TTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAEVEIMYGEGISRTGELVKIASDLDIIQKAGAWFSYNGEKIGQGSE
NAKRYLADHPELFDEIDRKVRVKFGLLEESEEESAMVVASEEIDDLALDLDNGIEIED

Nucleotide


Download         Length: 1137 bp        

>NTDB_id=82756 H7674_RS08535 WP_011285265.1 1755834..1756970(-) (recA) [Streptococcus pyogenes strain NIH35]
TTGGCAAAAAAATTAAAAAAGAATGAAGAAATCACTAAGAAGTTTGGTGACGAACGTCGCAAAGCCCTTGATGATGCTTT
GAAAAATATTGAAAAAGATTTTGGTAAGGGCGCAGTGATGCGATTAGGAGAACGTGCAGAGCAAAAAGTTCAGGTTATGA
GTTCAGGAAGTCTAGCTCTTGATATTGCGCTTGGAGCTGGTGGTTATCCTAAAGGACGTATCATCGAAATCTATGGTCCA
GAGTCTTCCGGTAAAACGACTGTGGCTTTACATGCTGTAGCACAAGCTCAAAAAGAAGGTGGAATCGCAGCCTTTATCGA
TGCCGAGCATGCGCTTGATCCAGCTTATGCTGCTGCGCTTGGGGTTAATATTGATGAACTCCTCTTGTCTCAACCAGATT
CTGGAGAACAAGGACTTGAAATTGCAGGTAAATTGATTGATTCTGGTGCGGTTGATCTGGTTGTTGTCGATTCAGTAGCA
GCTTTAGTGCCACGTGCTGAAATTGATGGTGATATTGGCGATAGCCATGTCGGATTGCAAGCACGTATGATGAGTCAGGC
TATGCGTAAATTATCAGCTTCTATTAATAAAACAAAAACTATCGCTATCTTTATTAACCAATTGCGTGAAAAAGTTGGTG
TCATGTTTGGAAATCCTGAAACAACACCAGGTGGTCGAGCTTTGAAATTCTATGCTTCTGTTCGGTTGGATGTGCGTGGA
ACAACTCAAATTAAAGGAACTGGTGACCAAAAAGATAGCAGCATTGGTAAGGAGACCAAAATCAAGGTTGTTAAAAACAA
GGTCGCTCCGCCATTTAAGGTAGCAGAAGTTGAAATCATGTATGGGGAAGGTATTTCTCGTACAGGGGAGCTTGTGAAAA
TTGCTTCTGATTTGGACATTATCCAAAAAGCAGGTGCTTGGTTCTCTTATAATGGTGAGAAGATTGGCCAAGGTTCTGAA
AATGCTAAGCGTTATTTGGCCGATCATCCAGAATTGTTTGATGAAATCGACCGTAAAGTACGTGTTAAATTTGGTTTGCT
TGAAGAAAGCGAAGAAGAATCTGCTATGGTAGTAGCATCAGAAGAAATCGATGATCTTGCTTTAGATTTAGATAATGGTA
TTGAAATTGAAGATTAA

Domains

Predicted by InterproScan.

recA bacterial DNA recombination protein (RecA)

(21-286)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q48QW7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recA Streptococcus pyogenes NZ131

98.942

100

0.989
  recA Streptococcus mutans UA159

87.467

100

0.886
  recA Streptococcus mitis NCTC 12261

85.379

100

0.865
  recA Streptococcus pneumoniae Rx1

84.675

100

0.862
  recA Streptococcus pneumoniae D39

84.675

100

0.862
  recA Streptococcus pneumoniae R6

84.675

100

0.862
  recA Streptococcus pneumoniae TIGR4

84.675

100

0.862
  recA Streptococcus mitis SK321

85.117

100

0.862
  recA Lactococcus lactis subsp. cremoris KW2

78.754

93.386

0.735
  recA Latilactobacillus sakei subsp. sakei 23K

70.623

89.153

0.63
  recA Bacillus subtilis subsp. subtilis str. 168

68.085

87.037

0.593
  recA Riemerella anatipestifer ATCC 11845 = DSM 15868

62.315

89.153

0.556
  recA Acinetobacter baumannii D1279779

59.207

93.386

0.553
  recA Acinetobacter baylyi ADP1

59.714

92.593

0.553
  recA Neisseria gonorrhoeae MS11

60.35

90.741

0.548
  recA Neisseria gonorrhoeae MS11

60.35

90.741

0.548
  recA Neisseria gonorrhoeae strain FA1090

60.35

90.741

0.548
  recA Glaesserella parasuis strain SC1401

60

89.947

0.54
  recA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

62.848

85.45

0.537
  recA Vibrio cholerae strain A1552

61.231

85.979

0.526
  recA Vibrio cholerae O1 biovar El Tor strain E7946

61.231

85.979

0.526
  recA Pseudomonas stutzeri DSM 10701

57.184

92.063

0.526
  recA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

59.215

87.566

0.519
  recA Helicobacter pylori strain NCTC11637

58.084

88.36

0.513
  recA Helicobacter pylori 26695

58.084

88.36

0.513
  recA Ralstonia pseudosolanacearum GMI1000

58.133

87.831

0.511

Multiple sequence alignment