Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   KUN2590_RS01885 Genome accession   NZ_AP023387
Coordinates   367917..368699 (+) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain NIH34     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 362917..373699
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KUN2590_RS01865 (SPNIH34_03150) - 363253..364218 (-) 966 WP_011054948.1 asparaginase -
  KUN2590_RS01870 (SPNIH34_03160) - 364291..365679 (+) 1389 WP_009881044.1 Cof-type HAD-IIB family hydrolase -
  KUN2590_RS01875 (SPNIH34_03170) - 365802..366254 (-) 453 WP_002992571.1 universal stress protein -
  KUN2590_RS01880 (SPNIH34_03180) - 366485..367699 (+) 1215 WP_010922605.1 pyridoxal phosphate-dependent aminotransferase -
  KUN2590_RS01885 (SPNIH34_03190) codY 367917..368699 (+) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  KUN2590_RS01890 (SPNIH34_03200) - 368846..369400 (+) 555 WP_002992568.1 cysteine hydrolase family protein -
  KUN2590_RS01895 (SPNIH34_03210) - 369859..370179 (+) 321 Protein_323 putative PEP-binding protein -
  KUN2590_RS01900 (SPNIH34_03220) gatC 370410..370712 (+) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  KUN2590_RS01905 (SPNIH34_03230) gatA 370712..372178 (+) 1467 WP_011054946.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  KUN2590_RS01910 (SPNIH34_03240) gatB 372178..373617 (+) 1440 WP_011054945.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=70253 KUN2590_RS01885 WP_002983278.1 367917..368699(+) (codY) [Streptococcus pyogenes strain NIH34]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=70253 KUN2590_RS01885 WP_002983278.1 367917..368699(+) (codY) [Streptococcus pyogenes strain NIH34]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAATTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504

Multiple sequence alignment