Detailed information    

insolico Bioinformatically predicted

Overview


Name   recA   Type   Machinery gene
Locus tag   EP180_RS04300 Genome accession   NZ_AP018385
Coordinates   738012..739058 (+) Length   348 a.a.
NCBI ID   WP_003688695.1    Uniprot ID   Q5F8M9
Organism   Neisseria gonorrhoeae strain FC498     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 730927..805974 738012..739058 within 0


Gene organization within MGE regions


Location: 730927..805974
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EP180_RS04260 (NgFC498_00745) - 730927..731997 (-) 1071 WP_010360162.1 tyrosine-type recombinase/integrase -
  EP180_RS04265 (NgFC498_00746) - 732206..732985 (-) 780 WP_003688701.1 ferredoxin--NADP reductase -
  EP180_RS04280 - 733577..733786 (-) 210 WP_003688699.1 hypothetical protein -
  EP180_RS04285 (NgFC498_00748) dinB 733885..734943 (+) 1059 WP_003695315.1 DNA polymerase IV -
  EP180_RS04290 (NgFC498_00749) rep 735013..737028 (-) 2016 WP_012503651.1 DNA helicase Rep -
  EP180_RS04295 (NgFC498_00750) aroD 737048..737812 (-) 765 WP_003688696.1 type I 3-dehydroquinate dehydratase -
  EP180_RS04300 (NgFC498_00751) recA 738012..739058 (+) 1047 WP_003688695.1 recombinase RecA Machinery gene
  EP180_RS04315 (NgFC498_00752) - 739711..740046 (-) 336 WP_003688693.1 YbaB/EbfC family nucleoid-associated protein -
  EP180_RS04320 (NgFC498_00753) dnaX 740127..742250 (-) 2124 WP_003695312.1 DNA polymerase III subunit gamma/tau -
  EP180_RS04325 (NgFC498_00754) mutL 742345..744309 (-) 1965 WP_047926984.1 DNA mismatch repair endonuclease MutL -
  EP180_RS04330 (NgFC498_00755) - 744453..744638 (+) 186 WP_003688687.1 DUF3460 family protein -
  EP180_RS04335 (NgFC498_00756) - 744649..745317 (+) 669 WP_003688686.1 class I SAM-dependent methyltransferase -
  EP180_RS04340 (NgFC498_00757) - 745317..746030 (+) 714 WP_003697104.1 tetratricopeptide repeat protein -
  EP180_RS04345 (NgFC498_00758) purE 746078..746563 (+) 486 WP_003688684.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  EP180_RS04355 (NgFC498_00759) - 746775..747582 (-) 808 Protein_754 transposase -
  EP180_RS04365 - 747956..748321 (+) 366 Protein_755 transposase -
  EP180_RS04370 (NgFC498_00761) - 748328..749353 (+) 1026 Protein_756 autotransporter outer membrane beta-barrel domain-containing protein -
  EP180_RS04375 (NgFC498_00762) - 749548..750204 (-) 657 WP_003688682.1 response regulator -
  EP180_RS04380 (NgFC498_00763) - 750201..751970 (-) 1770 WP_003688681.1 histidine kinase -
  EP180_RS04385 (NgFC498_00764) - 752177..752791 (+) 615 WP_047917856.1 molybdenum cofactor guanylyltransferase -
  EP180_RS04390 (NgFC498_00765) - 752954..753571 (+) 618 WP_010358100.1 riboflavin synthase -
  EP180_RS04395 - 753579..754443 (+) 865 Protein_761 ATP-binding protein -
  EP180_RS04400 (NgFC498_00768) - 754456..754890 (-) 435 WP_003688677.1 Spy/CpxP family protein refolding chaperone -
  EP180_RS04405 (NgFC498_00769) rpe 755036..755719 (+) 684 WP_003688675.1 ribulose-phosphate 3-epimerase -
  EP180_RS04415 (NgFC498_00770) ruvB 755964..756995 (-) 1032 WP_003688673.1 Holliday junction branch migration DNA helicase RuvB -
  EP180_RS04420 (NgFC498_00771) - 757077..757385 (-) 309 WP_003688671.1 hypothetical protein -
  EP180_RS04430 (NgFC498_00772) - 757804..759036 (-) 1233 WP_003702731.1 multifunctional CCA addition/repair protein -
  EP180_RS04435 (NgFC498_00773) - 759115..760743 (-) 1629 WP_010951119.1 ABC-F family ATPase -
  EP180_RS04440 (NgFC498_00774) - 760893..761267 (+) 375 WP_003688664.1 arsenate reductase -
  EP180_RS04445 (NgFC498_00775) - 761316..762854 (+) 1539 WP_003695299.1 SurA N-terminal domain-containing protein -
  EP180_RS04450 (NgFC498_00776) recR 762921..763538 (+) 618 WP_003688660.1 recombination mediator RecR -
  EP180_RS04455 (NgFC498_00777) - 763594..763872 (-) 279 WP_003688659.1 hypothetical protein -
  EP180_RS04470 (NgFC498_00778) - 764098..765345 (+) 1248 WP_003691197.1 lipoprotein-releasing ABC transporter permease subunit -
  EP180_RS04475 (NgFC498_00779) lolD 765338..766033 (+) 696 WP_003688655.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  EP180_RS04480 (NgFC498_00780) recD 766100..767845 (+) 1746 WP_003688652.1 exodeoxyribonuclease V subunit alpha Machinery gene
  EP180_RS04485 - 767917..768563 (-) 647 Protein_775 methyltransferase -
  EP180_RS04490 (NgFC498_00782) - 768571..769533 (+) 963 WP_127466217.1 IS110 family transposase -
  EP180_RS13575 - 769662..770121 (-) 460 Protein_777 methyltransferase -
  EP180_RS04500 (NgFC498_00784) lon 770373..772835 (+) 2463 WP_003688644.1 endopeptidase La -
  EP180_RS04505 (NgFC498_00785) - 773017..773286 (+) 270 WP_003688640.1 HU family DNA-binding protein -
  EP180_RS04510 (NgFC498_00786) - 773462..773896 (-) 435 WP_003688638.1 hypothetical protein -
  EP180_RS04515 (NgFC498_00787) - 773889..775196 (-) 1308 WP_103195193.1 homoserine dehydrogenase -
  EP180_RS04520 (NgFC498_00788) - 775392..775763 (+) 372 WP_003688636.1 Mth938-like domain-containing protein -
  EP180_RS04525 (NgFC498_00789) - 775840..777762 (+) 1923 WP_003691184.1 ATP-binding cassette domain-containing protein -
  EP180_RS04530 - 777725..778144 (+) 420 WP_229692939.1 DUF4124 domain-containing protein -
  EP180_RS04535 (NgFC498_00790) - 778235..778747 (+) 513 WP_003693093.1 hypothetical protein -
  EP180_RS04540 (NgFC498_00791) - 779177..779872 (-) 696 WP_033910499.1 DUF4400 domain-containing protein -
  EP180_RS04545 (NgFC498_00792) traD 779862..781904 (-) 2043 WP_012503640.1 type IV conjugative transfer system coupling protein TraD -
  EP180_RS04550 (NgFC498_00793) mobH 781901..784453 (-) 2553 WP_012503639.1 MobH family relaxase -
  EP180_RS04555 (NgFC498_00794) - 784450..784869 (-) 420 WP_003693104.1 hypothetical protein -
  EP180_RS04560 (NgFC498_00795) - 785380..785841 (+) 462 WP_012503638.1 lytic transglycosylase domain-containing protein -
  EP180_RS04565 (NgFC498_00796) - 785811..786332 (+) 522 WP_003695285.1 OmpA family protein -
  EP180_RS04570 (NgFC498_00797) traA 786388..786684 (+) 297 WP_003697092.1 TraA family conjugative transfer protein -
  EP180_RS04575 (NgFC498_00798) traL 786706..786987 (+) 282 WP_003693110.1 type IV conjugative transfer system protein TraL -
  EP180_RS04580 (NgFC498_00799) - 786984..787649 (+) 666 WP_003704028.1 conjugal transfer protein TraE -
  EP180_RS04585 (NgFC498_00800) - 787651..788385 (+) 735 WP_003693114.1 TraK domain-containing protein -
  EP180_RS04590 (NgFC498_00801) - 788387..789700 (+) 1314 WP_003697090.1 TrbI/VirB10 family protein -
  EP180_RS04595 (NgFC498_00802) - 789710..790429 (+) 720 WP_003693119.1 DsbC family protein -
  EP180_RS04600 (NgFC498_00803) - 790426..791007 (+) 582 WP_017146802.1 TraV family lipoprotein -
  EP180_RS04605 (NgFC498_00804) traC 791017..793593 (+) 2577 WP_003693122.1 type IV secretion system protein TraC -
  EP180_RS04610 (NgFC498_00805) - 793621..794169 (+) 549 WP_003695274.1 hypothetical protein -
  EP180_RS04615 (NgFC498_00806) - 794169..794714 (+) 546 WP_003704029.1 S26 family signal peptidase -
  EP180_RS04620 (NgFC498_00807) - 794723..795379 (+) 657 WP_003693128.1 hypothetical protein -
  EP180_RS04625 (NgFC498_00808) - 795376..796494 (+) 1119 WP_003695266.1 TraU family protein -
  EP180_RS04630 (NgFC498_00809) trbC 796509..797261 (+) 753 WP_003699946.1 type-F conjugative transfer system pilin assembly protein TrbC -
  EP180_RS04635 (NgFC498_00810) - 797258..798502 (+) 1245 WP_003695263.1 hypothetical protein -
  EP180_RS04640 (NgFC498_00811) traN 798541..800082 (+) 1542 WP_226876101.1 conjugal transfer protein TraN -
  EP180_RS04645 (NgFC498_00812) - 800069..800494 (+) 426 WP_003693140.1 hypothetical protein -
  EP180_RS04650 (NgFC498_00813) - 800506..801282 (+) 777 WP_012503632.1 thioredoxin family protein -
  EP180_RS04655 (NgFC498_00814) - 801454..802965 (+) 1512 WP_041421275.1 conjugal transfer protein TraH -
  EP180_RS04660 (NgFC498_00815) - 802972..805974 (+) 3003 WP_012503630.1 conjugal transfer protein TraG N-terminal domain-containing protein -

Sequence


Protein


Download         Length: 348 a.a.        Molecular weight: 37642.87 Da        Isoelectric Point: 4.8330

>NTDB_id=69266 EP180_RS04300 WP_003688695.1 738012..739058(+) (recA) [Neisseria gonorrhoeae strain FC498]
MSDDKSKALAAALAQIEKSFGKGAIMKMDGSQQEENLEVISTGSLGLDLALGVGGLPRGRIVEIFGPESSGKTTLCLEAV
AQCQKNGGVCAFVDAEHAFDPVYARKLGVKVEELYLSQPDTGEQALEICDTLVRSGGIDMVVVDSVAALVPKAEIEGDMG
DSHVGLQARLMSQALRKLTGHIKKTNTLVVFINQIRMKIGVMFGSPETTTGGNALKFYSSVRLDIRRTGSIKKGEEVLGN
ETRVKVIKNKVAPPFRQAEFDILYGEGISWEGELIDIGVKNDIINKSGAWYSYNGAKIGQGKDNVRVWLKENPEISDEID
AKIRALNGVEMHITEGTQDETDGERPEE

Nucleotide


Download         Length: 1047 bp        

>NTDB_id=69266 EP180_RS04300 WP_003688695.1 738012..739058(+) (recA) [Neisseria gonorrhoeae strain FC498]
ATGTCAGACGACAAAAGCAAAGCCCTTGCCGCCGCACTGGCGCAAATCGAAAAAAGTTTCGGCAAAGGCGCCATCATGAA
AATGGACGGCAGCCAGCAGGAAGAAAACCTCGAAGTCATTTCCACCGGATCGCTCGGATTAGACCTCGCCCTCGGAGTCG
GCGGCCTGCCGCGCGGGCGCATCGTCGAAATCTTCGGCCCCGAATCCTCCGGCAAAACCACACTCTGCCTCGAAGCCGTC
GCCCAATGCCAGAAAAACGGCGGCGTGTGCGCCTTTGTCGATGCCGAACACGCCTTCGATCCCGTTTACGCCCGCAAACT
CGGCGTAAAAGTCGAAGAGCTTTACCTGTCCCAGCCCGATACCGGCGAACAGGCTTTGGAAATCTGCGACACGCTCGTCC
GTTCGGGCGGCATAGATATGGTAGTCGTCGATTCCGTAGCCGCACTCGTCCCCAAAGCCGAAATCGAAGGCGATATGGGG
GACAGCCACGTCGGACTGCAGGCGCGCCTGATGAGTCAGGCTTTGCGCAAACTGACCGGACACATCAAAAAAACCAATAC
GCTGGTTGTGTTCATCAACCAAATCCGAATGAAGATCGGCGTAATGTTCGGCAGCCCCGAGACCACGACCGGCGGCAACG
CGCTGAAATTCTATTCTTCCGTCCGCCTCGACATCCGCCGCACCGGATCCATCAAAAAAGGCGAAGAAGTATTGGGCAAC
GAAACCCGCGTCAAAGTCATCAAAAACAAAGTCGCCCCCCCGTTCCGTCAGGCAGAGTTTGACATCCTCTACGGAGAAGG
CATCAGTTGGGAAGGCGAATTGATCGACATCGGCGTGAAAAACGACATCATCAACAAATCCGGCGCGTGGTACAGCTACA
ACGGCGCGAAAATCGGTCAGGGCAAAGACAACGTCCGCGTCTGGCTGAAAGAAAACCCCGAAATTTCCGACGAAATCGAC
GCAAAAATCCGCGCCCTCAACGGCGTAGAAATGCACATCACCGAAGGGACGCAGGACGAAACCGACGGCGAACGACCCGA
AGAATAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q5F8M9

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recA Neisseria gonorrhoeae MS11

100

100

1

  recA Neisseria gonorrhoeae strain FA1090

100

100

1

  recA Neisseria gonorrhoeae MS11

100

100

1

  recA Ralstonia pseudosolanacearum GMI1000

74.468

94.54

0.704

  recA Vibrio cholerae O1 biovar El Tor strain E7946

66.949

100

0.681

  recA Vibrio cholerae strain A1552

66.949

100

0.681

  recA Glaesserella parasuis strain SC1401

67.521

100

0.681

  recA Pseudomonas stutzeri DSM 10701

71.692

93.391

0.67

  recA Acinetobacter baylyi ADP1

66.859

99.713

0.667

  recA Acinetobacter baumannii D1279779

65.517

100

0.655

  recA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

65.103

97.989

0.638

  recA Riemerella anatipestifer ATCC 11845 = DSM 15868

67.073

94.253

0.632

  recA Helicobacter pylori 26695

67.077

93.391

0.626

  recA Helicobacter pylori strain NCTC11637

66.769

93.391

0.624

  recA Bacillus subtilis subsp. subtilis str. 168

65.138

93.966

0.612

  recA Streptococcus mutans UA159

60.684

100

0.612

  recA Streptococcus pneumoniae TIGR4

59.544

100

0.601

  recA Streptococcus pneumoniae Rx1

59.544

100

0.601

  recA Streptococcus pneumoniae D39

59.544

100

0.601

  recA Streptococcus pneumoniae R6

59.544

100

0.601

  recA Streptococcus mitis NCTC 12261

59.884

98.851

0.592

  recA Latilactobacillus sakei subsp. sakei 23K

62.691

93.966

0.589

  recA Streptococcus pyogenes NZ131

61.963

93.678

0.58

  recA Streptococcus mitis SK321

60.606

94.828

0.575

  recA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

60.121

95.115

0.572

  recA Lactococcus lactis subsp. cremoris KW2

60.303

94.828

0.572


Multiple sequence alignment