Detailed information
Bioinformatically predicted
Overview
| Name | recA | Type | Machinery gene |
| Locus tag | LA362_RS12395 | Genome accession | NZ_CP083616 |
| Coordinates | 2756308..2757354 (-) | Length | 348 a.a. |
| NCBI ID | WP_021364420.1 | Uniprot ID | A0A9X8RFQ1 |
| Organism | Clostridioides difficile strain FDAARGOS_1528 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 2710071..2775710 | 2756308..2757354 | within | 0 |
Gene organization within MGE regions
Location: 2710071..2775710
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LA362_RS12170 (LA362_12210) | - | 2710722..2711420 (-) | 699 | WP_003438451.1 | putative phage tail protein | - |
| LA362_RS12175 (LA362_12215) | - | 2711417..2712469 (-) | 1053 | WP_003438450.1 | baseplate J/gp47 family protein | - |
| LA362_RS12180 (LA362_12220) | - | 2712462..2712890 (-) | 429 | WP_003438449.1 | DUF2634 domain-containing protein | - |
| LA362_RS12185 (LA362_12225) | - | 2712890..2713216 (-) | 327 | WP_003438447.1 | DUF2577 domain-containing protein | - |
| LA362_RS12190 (LA362_12230) | - | 2713232..2714761 (-) | 1530 | WP_003438440.1 | NlpC/P60 family protein | - |
| LA362_RS12195 (LA362_12235) | - | 2715043..2715465 (-) | 423 | WP_003428168.1 | phage baseplate protein | - |
| LA362_RS12200 (LA362_12240) | - | 2715465..2717918 (-) | 2454 | WP_003438437.1 | hypothetical protein | - |
| LA362_RS12205 (LA362_12245) | - | 2717918..2718085 (-) | 168 | WP_003419648.1 | hypothetical protein | - |
| LA362_RS12210 (LA362_12250) | - | 2718112..2718558 (-) | 447 | WP_003419647.1 | phage tail assembly chaperone | - |
| LA362_RS12215 (LA362_12255) | - | 2718672..2719100 (-) | 429 | WP_003419646.1 | phage tail tube protein | - |
| LA362_RS12220 (LA362_12260) | - | 2719114..2720178 (-) | 1065 | WP_003438414.1 | phage tail sheath subtilisin-like domain-containing protein | - |
| LA362_RS12225 (LA362_12265) | - | 2720183..2720626 (-) | 444 | WP_003438413.1 | phage tail terminator family protein | - |
| LA362_RS12230 (LA362_12270) | - | 2720875..2721315 (-) | 441 | WP_003428183.1 | hypothetical protein | - |
| LA362_RS12235 (LA362_12275) | - | 2721420..2721617 (-) | 198 | WP_003419641.1 | helix-turn-helix transcriptional regulator | - |
| LA362_RS12240 (LA362_12280) | - | 2721786..2722106 (+) | 321 | WP_003428185.1 | XRE family transcriptional regulator | - |
| LA362_RS12245 (LA362_12285) | - | 2722188..2722694 (+) | 507 | WP_003428186.1 | ImmA/IrrE family metallo-endopeptidase | - |
| LA362_RS12250 (LA362_12290) | - | 2723395..2724150 (+) | 756 | WP_009889131.1 | peptidylprolyl isomerase | - |
| LA362_RS12255 (LA362_12295) | - | 2724293..2724721 (-) | 429 | WP_009889129.1 | CBS domain-containing protein | - |
| LA362_RS12260 (LA362_12300) | - | 2725142..2725342 (-) | 201 | WP_003419624.1 | cold-shock protein | - |
| LA362_RS12265 (LA362_12305) | - | 2725525..2726679 (-) | 1155 | WP_009902426.1 | amidase domain-containing protein | - |
| LA362_RS12270 (LA362_12310) | - | 2726930..2727751 (+) | 822 | WP_021364435.1 | pyridoxamine kinase | - |
| LA362_RS12275 (LA362_12315) | - | 2727827..2729215 (-) | 1389 | WP_021364432.1 | two-component system sensor histidine kinase | - |
| LA362_RS12280 (LA362_12320) | - | 2729350..2730108 (-) | 759 | WP_009902423.1 | lantibiotic immunity ABC transporter MutG family permease subunit | - |
| LA362_RS12285 (LA362_12325) | - | 2730110..2730826 (-) | 717 | WP_009896246.1 | lantibiotic immunity ABC transporter MutE/EpiE family permease subunit | - |
| LA362_RS12290 (LA362_12330) | - | 2730828..2731535 (-) | 708 | WP_009902422.1 | lantibiotic protection ABC transporter ATP-binding protein | - |
| LA362_RS12295 (LA362_12335) | - | 2731651..2732187 (-) | 537 | WP_003428196.1 | lipoprotein | - |
| LA362_RS12300 (LA362_12340) | - | 2732289..2733359 (-) | 1071 | WP_021364425.1 | DUF4097 family beta strand repeat-containing protein | - |
| LA362_RS12305 (LA362_12345) | - | 2733352..2734410 (-) | 1059 | WP_021367719.1 | DUF1700 domain-containing protein | - |
| LA362_RS12310 (LA362_12350) | - | 2734397..2734729 (-) | 333 | WP_009889116.1 | PadR family transcriptional regulator | - |
| LA362_RS12315 (LA362_12355) | - | 2734928..2736049 (+) | 1122 | WP_003438374.1 | MGDG synthase family glycosyltransferase | - |
| LA362_RS12320 (LA362_12360) | - | 2736177..2738075 (-) | 1899 | WP_003428202.1 | glutamine synthetase | - |
| LA362_RS12325 (LA362_12365) | - | 2738390..2739166 (+) | 777 | WP_009896237.1 | 3'-5' exonuclease | - |
| LA362_RS12330 (LA362_12370) | - | 2739258..2740010 (-) | 753 | WP_003438367.1 | exodeoxyribonuclease III | - |
| LA362_RS12335 (LA362_12375) | galT | 2740171..2741121 (-) | 951 | WP_009889113.1 | galactose-1-phosphate uridylyltransferase | - |
| LA362_RS12340 (LA362_12380) | - | 2741506..2742702 (+) | 1197 | WP_003438357.1 | pyridoxal phosphate-dependent aminotransferase | - |
| LA362_RS12345 (LA362_12385) | - | 2742814..2744160 (-) | 1347 | WP_009902417.1 | 6-phospho-alpha-glucosidase | - |
| LA362_RS12350 (LA362_12390) | - | 2744293..2745045 (-) | 753 | WP_009892977.1 | MurR/RpiR family transcriptional regulator | - |
| LA362_RS12355 (LA362_12395) | - | 2745193..2746770 (-) | 1578 | WP_021364419.1 | PTS transporter subunit EIIC | - |
| LA362_RS12360 (LA362_12400) | - | 2747182..2747634 (-) | 453 | WP_003419561.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
| LA362_RS12365 (LA362_12405) | purB | 2747945..2749390 (-) | 1446 | WP_003438353.1 | adenylosuccinate lyase | - |
| LA362_RS12370 (LA362_12410) | - | 2749534..2750442 (-) | 909 | WP_009889110.1 | tyrosine-type recombinase/integrase | - |
| LA362_RS12375 (LA362_12415) | - | 2750699..2751523 (+) | 825 | WP_003438350.1 | undecaprenyl-diphosphate phosphatase | - |
| LA362_RS12380 (LA362_12420) | lepB | 2751563..2752093 (+) | 531 | WP_009902411.1 | signal peptidase I | - |
| LA362_RS12385 (LA362_12425) | - | 2752175..2753956 (-) | 1782 | WP_003438344.1 | UvrD-helicase domain-containing protein | - |
| LA362_RS12390 (LA362_12430) | rny | 2754591..2756132 (-) | 1542 | WP_003428216.1 | ribonuclease Y | - |
| LA362_RS12395 (LA362_12435) | recA | 2756308..2757354 (-) | 1047 | WP_021364420.1 | recombinase RecA | Machinery gene |
| LA362_RS12400 (LA362_12440) | pgsA | 2757642..2758184 (-) | 543 | WP_009889106.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase | - |
| LA362_RS12405 (LA362_12445) | rimO | 2758171..2759505 (-) | 1335 | WP_003433320.1 | 30S ribosomal protein S12 methylthiotransferase RimO | - |
| LA362_RS12410 (LA362_12450) | mnmH | 2759499..2760557 (-) | 1059 | WP_003433322.1 | tRNA 2-selenouridine(34) synthase MnmH | - |
| LA362_RS12415 (LA362_12455) | - | 2760560..2762971 (-) | 2412 | WP_003438328.1 | FtsK/SpoIIIE family DNA translocase | - |
| LA362_RS12420 (LA362_12460) | - | 2763094..2763828 (-) | 735 | WP_021364422.1 | ClpP family protease | - |
| LA362_RS12425 (LA362_12465) | dapG | 2763941..2765164 (-) | 1224 | WP_003438324.1 | aspartate kinase | - |
| LA362_RS12430 (LA362_12470) | - | 2765174..2765419 (-) | 246 | WP_021364423.1 | YlmC/YmxH family sporulation protein | - |
| LA362_RS12435 (LA362_12475) | - | 2765454..2766701 (-) | 1248 | WP_009902409.1 | M16 family metallopeptidase | - |
| LA362_RS12440 (LA362_12480) | - | 2766859..2767602 (-) | 744 | WP_003438319.1 | polysaccharide deacetylase family protein | - |
| LA362_RS12445 (LA362_12485) | pnp | 2767868..2769979 (-) | 2112 | WP_003438316.1 | polyribonucleotide nucleotidyltransferase | - |
| LA362_RS12450 (LA362_12490) | - | 2770104..2770949 (-) | 846 | WP_009889099.1 | DegV family protein | - |
| LA362_RS12455 (LA362_12495) | rpsO | 2771189..2771446 (-) | 258 | WP_003419491.1 | 30S ribosomal protein S15 | - |
| LA362_RS12460 (LA362_12500) | - | 2771550..2772479 (-) | 930 | WP_003438310.1 | bifunctional riboflavin kinase/FAD synthetase | - |
| LA362_RS12465 (LA362_12505) | truB | 2772610..2773515 (-) | 906 | WP_003428232.1 | tRNA pseudouridine(55) synthase TruB | - |
| LA362_RS12470 (LA362_12510) | - | 2773528..2773833 (-) | 306 | Protein_2490 | DHH family phosphoesterase | - |
| LA362_RS12475 (LA362_12515) | tnpB | 2773951..2775069 (-) | 1119 | WP_032548186.1 | IS200/IS605 family element RNA-guided endonuclease TnpB | - |
Sequence
Protein
Download Length: 348 a.a. Molecular weight: 37389.74 Da Isoelectric Point: 4.8236
>NTDB_id=606676 LA362_RS12395 WP_021364420.1 2756308..2757354(-) (recA) [Clostridioides difficile strain FDAARGOS_1528]
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEI
DEKVRAFYNLNEEHEESGISVSKEIVEE
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEI
DEKVRAFYNLNEEHEESGISVSKEIVEE
Nucleotide
Download Length: 1047 bp
>NTDB_id=606676 LA362_RS12395 WP_021364420.1 2756308..2757354(-) (recA) [Clostridioides difficile strain FDAARGOS_1528]
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGACATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAAACTACTGTTGCGCTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATATGCAAAAGC
TTTGGGTGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGATTCTCATGTAGGTTTACAAGCTAGACTTATGTCACAAGCACTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCGGAAACTACTACTGGAGGAC
GTGCACTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGATACAATAAAACAAGGTGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTTGTTAAAAACAAAGTAGCACCACCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGAATTTCAAAAATTGGAGACCTTTTAGATATAGCTGCTGATGTAGATATAGTTAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAAGATAATTTAGATTTAACTACTGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAATCAGGTATTTCAGTATCAAAAGAAATTGTAGA
AGAATAA
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGACATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAAACTACTGTTGCGCTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATATGCAAAAGC
TTTGGGTGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGATTCTCATGTAGGTTTACAAGCTAGACTTATGTCACAAGCACTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCGGAAACTACTACTGGAGGAC
GTGCACTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGATACAATAAAACAAGGTGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTTGTTAAAAACAAAGTAGCACCACCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGAATTTCAAAAATTGGAGACCTTTTAGATATAGCTGCTGATGTAGATATAGTTAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAAGATAATTTAGATTTAACTACTGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAATCAGGTATTTCAGTATCAAAAGAAATTGTAGA
AGAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.