Detailed information
Bioinformatically predicted
Overview
| Name | recA | Type | Machinery gene |
| Locus tag | KK112_RS06665 | Genome accession | NZ_CP075685 |
| Coordinates | 1393279..1394325 (+) | Length | 348 a.a. |
| NCBI ID | WP_003419530.1 | Uniprot ID | A0AAX3GVV5 |
| Organism | Clostridioides difficile strain MT5121 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1388489..1439123 | 1393279..1394325 | within | 0 |
Gene organization within MGE regions
Location: 1388489..1439123
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KK112_RS06650 (KK112_06650) | mnmH | 1390097..1391155 (+) | 1059 | WP_003419524.1 | tRNA 2-selenouridine(34) synthase MnmH | - |
| KK112_RS06655 (KK112_06655) | rimO | 1391149..1392483 (+) | 1335 | WP_003419527.1 | 30S ribosomal protein S12 methylthiotransferase RimO | - |
| KK112_RS06660 (KK112_06660) | pgsA | 1392470..1393012 (+) | 543 | WP_009905407.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase | - |
| KK112_RS06665 (KK112_06665) | recA | 1393279..1394325 (+) | 1047 | WP_003419530.1 | recombinase RecA | Machinery gene |
| KK112_RS06670 (KK112_06670) | rny | 1394501..1396042 (+) | 1542 | WP_003428216.1 | ribonuclease Y | - |
| KK112_RS06675 (KK112_06675) | - | 1396352..1398688 (+) | 2337 | WP_003419542.1 | diguanylate cyclase | - |
| KK112_RS06680 (KK112_06680) | - | 1399494..1399592 (+) | 99 | Protein_1227 | transposase | - |
| KK112_RS06685 (KK112_06685) | tnpB | 1399594..1400712 (+) | 1119 | WP_041160402.1 | IS200/IS605 family element RNA-guided endonuclease TnpB | - |
| KK112_RS06690 (KK112_06690) | - | 1401044..1402825 (+) | 1782 | WP_003419546.1 | UvrD-helicase domain-containing protein | - |
| KK112_RS06695 (KK112_06695) | lepB | 1402905..1403435 (-) | 531 | WP_009905409.1 | signal peptidase I | - |
| KK112_RS06700 (KK112_06700) | - | 1403475..1404299 (-) | 825 | WP_009905410.1 | undecaprenyl-diphosphate phosphatase | - |
| KK112_RS06705 (KK112_06705) | - | 1404556..1405467 (+) | 912 | WP_022615208.1 | tyrosine-type recombinase/integrase | - |
| KK112_RS06710 (KK112_06710) | purB | 1405606..1407051 (+) | 1446 | WP_003419557.1 | adenylosuccinate lyase | - |
| KK112_RS06715 (KK112_06715) | - | 1407352..1407804 (+) | 453 | WP_003419561.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
| KK112_RS06720 (KK112_06720) | - | 1408023..1409219 (-) | 1197 | WP_003419570.1 | pyridoxal phosphate-dependent aminotransferase | - |
| KK112_RS06725 (KK112_06725) | galT | 1409604..1410554 (+) | 951 | WP_003419573.1 | galactose-1-phosphate uridylyltransferase | - |
| KK112_RS06730 (KK112_06730) | - | 1410675..1411427 (+) | 753 | WP_003419575.1 | exodeoxyribonuclease III | - |
| KK112_RS06735 (KK112_06735) | - | 1411519..1412295 (-) | 777 | WP_003419578.1 | 3'-5' exonuclease | - |
| KK112_RS06740 (KK112_06740) | - | 1412610..1414508 (+) | 1899 | WP_003419583.1 | glutamine synthetase | - |
| KK112_RS06745 (KK112_06745) | - | 1414636..1415757 (-) | 1122 | WP_003419591.1 | MGDG synthase family glycosyltransferase | - |
| KK112_RS06750 (KK112_06750) | - | 1415956..1416288 (+) | 333 | WP_009905416.1 | PadR family transcriptional regulator | - |
| KK112_RS06755 (KK112_06755) | - | 1416275..1417333 (+) | 1059 | WP_003419595.1 | DUF1700 domain-containing protein | - |
| KK112_RS06760 (KK112_06760) | - | 1417326..1418396 (+) | 1071 | WP_003419596.1 | DUF4097 family beta strand repeat-containing protein | - |
| KK112_RS06765 (KK112_06765) | - | 1418498..1419034 (+) | 537 | WP_003419598.1 | hypothetical protein | - |
| KK112_RS06770 (KK112_06770) | - | 1419154..1419861 (+) | 708 | WP_009905418.1 | lantibiotic protection ABC transporter ATP-binding protein | - |
| KK112_RS06775 (KK112_06775) | - | 1419863..1420582 (+) | 720 | WP_003419603.1 | lantibiotic immunity ABC transporter MutE/EpiE family permease subunit | - |
| KK112_RS06780 (KK112_06780) | - | 1420584..1421354 (+) | 771 | WP_003419609.1 | lantibiotic immunity ABC transporter MutG family permease subunit | - |
| KK112_RS06785 (KK112_06785) | - | 1421488..1422879 (+) | 1392 | WP_029158131.1 | sensor histidine kinase | - |
| KK112_RS06790 (KK112_06790) | - | 1422955..1423776 (-) | 822 | WP_003419615.1 | pyridoxamine kinase | - |
| KK112_RS06795 (KK112_06795) | - | 1424027..1425181 (+) | 1155 | WP_009905420.1 | amidase domain-containing protein | - |
| KK112_RS06800 (KK112_06800) | - | 1425364..1425564 (+) | 201 | WP_003419624.1 | cold-shock protein | - |
| KK112_RS06805 (KK112_06805) | - | 1425985..1426413 (+) | 429 | WP_009889129.1 | CBS domain-containing protein | - |
| KK112_RS06810 (KK112_06810) | - | 1426556..1427311 (-) | 756 | WP_009889131.1 | peptidylprolyl isomerase | - |
| KK112_RS06815 (KK112_06815) | - | 1428012..1428518 (-) | 507 | WP_003419636.1 | ImmA/IrrE family metallo-endopeptidase | - |
| KK112_RS06820 (KK112_06820) | - | 1428600..1428920 (-) | 321 | WP_003419639.1 | XRE family transcriptional regulator | - |
| KK112_RS06825 (KK112_06825) | - | 1429089..1429286 (+) | 198 | WP_003419641.1 | helix-turn-helix transcriptional regulator | - |
| KK112_RS06830 (KK112_06830) | - | 1429390..1429830 (+) | 441 | WP_003419643.1 | hypothetical protein | - |
| KK112_RS06835 (KK112_06835) | - | 1430079..1430522 (+) | 444 | WP_003419644.1 | phage tail terminator family protein | - |
| KK112_RS06840 (KK112_06840) | - | 1430527..1431591 (+) | 1065 | WP_003419645.1 | phage tail sheath subtilisin-like domain-containing protein | - |
| KK112_RS06845 (KK112_06845) | - | 1431605..1432033 (+) | 429 | WP_003419646.1 | phage tail tube protein | - |
| KK112_RS06850 (KK112_06850) | - | 1432147..1432593 (+) | 447 | WP_003419647.1 | phage tail assembly chaperone | - |
| KK112_RS06855 (KK112_06855) | - | 1432620..1432787 (+) | 168 | WP_003419648.1 | hypothetical protein | - |
| KK112_RS06860 (KK112_06860) | - | 1432787..1435240 (+) | 2454 | WP_003419649.1 | hypothetical protein | - |
| KK112_RS06865 (KK112_06865) | - | 1435240..1435662 (+) | 423 | WP_003419651.1 | phage baseplate protein | - |
| KK112_RS06870 (KK112_06870) | - | 1435944..1437473 (+) | 1530 | WP_003419653.1 | NlpC/P60 family protein | - |
| KK112_RS06875 (KK112_06875) | - | 1437489..1437815 (+) | 327 | WP_003419655.1 | DUF2577 family protein | - |
| KK112_RS06880 (KK112_06880) | - | 1437815..1438243 (+) | 429 | WP_003419656.1 | DUF2634 domain-containing protein | - |
Sequence
Protein
Download Length: 348 a.a. Molecular weight: 37387.68 Da Isoelectric Point: 4.8236
>NTDB_id=570162 KK112_RS06665 WP_003419530.1 1393279..1394325(+) (recA) [Clostridioides difficile strain MT5121]
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTNEI
DEKVRAFYNLNEEHEEAGNSVSKEIVEE
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTNEI
DEKVRAFYNLNEEHEEAGNSVSKEIVEE
Nucleotide
Download Length: 1047 bp
>NTDB_id=570162 KK112_RS06665 WP_003419530.1 1393279..1394325(+) (recA) [Clostridioides difficile strain MT5121]
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGATATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAGACTACTGTTGCACTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATACGCAAAAGC
TTTGGGCGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGACTCTCACGTAGGGTTACAAGCTAGACTTATGTCGCAAGCTCTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCAGAAACTACTACTGGAGGAC
GTGCATTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGACACAATAAAACAAGGAGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTCGTTAAAAATAAAGTAGCACCTCCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGGATTTCAAAAATTGGAGACCTTCTAGATATAGCTGCTGATGTAGATATAGTAAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAGGATAATTTAGATTTAACTAATGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAAGCAGGTAATTCAGTATCAAAAGAAATTGTAGA
AGAATAA
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGATATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAGACTACTGTTGCACTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATACGCAAAAGC
TTTGGGCGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGACTCTCACGTAGGGTTACAAGCTAGACTTATGTCGCAAGCTCTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCAGAAACTACTACTGGAGGAC
GTGCATTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGACACAATAAAACAAGGAGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTCGTTAAAAATAAAGTAGCACCTCCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGGATTTCAAAAATTGGAGACCTTCTAGATATAGCTGCTGATGTAGATATAGTAAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAGGATAATTTAGATTTAACTAATGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAAGCAGGTAATTCAGTATCAAAAGAAATTGTAGA
AGAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.