Detailed information
Bioinformatically predicted
Overview
| Name | recA | Type | Machinery gene |
| Locus tag | JMW46_RS16010 | Genome accession | NZ_CP068553 |
| Coordinates | 3512715..3513761 (+) | Length | 348 a.a. |
| NCBI ID | WP_003419530.1 | Uniprot ID | A0AAX3GVV5 |
| Organism | Clostridioides difficile strain 2016 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 3507925..3558559 | 3512715..3513761 | within | 0 |
Gene organization within MGE regions
Location: 3507925..3558559
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JMW46_RS15995 (JMW46_15995) | mnmH | 3509533..3510591 (+) | 1059 | WP_003419524.1 | tRNA 2-selenouridine(34) synthase MnmH | - |
| JMW46_RS16000 (JMW46_16000) | rimO | 3510585..3511919 (+) | 1335 | WP_003419527.1 | 30S ribosomal protein S12 methylthiotransferase RimO | - |
| JMW46_RS16005 (JMW46_16005) | pgsA | 3511906..3512448 (+) | 543 | WP_009905407.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase | - |
| JMW46_RS16010 (JMW46_16010) | recA | 3512715..3513761 (+) | 1047 | WP_003419530.1 | recombinase RecA | Machinery gene |
| JMW46_RS16015 (JMW46_16015) | rny | 3513937..3515478 (+) | 1542 | WP_003428216.1 | ribonuclease Y | - |
| JMW46_RS16020 (JMW46_16020) | - | 3515788..3518124 (+) | 2337 | WP_003419542.1 | diguanylate cyclase | - |
| JMW46_RS16025 (JMW46_16025) | - | 3518930..3519028 (+) | 99 | Protein_3100 | transposase | - |
| JMW46_RS16030 (JMW46_16030) | tnpB | 3519030..3520148 (+) | 1119 | WP_041160402.1 | IS200/IS605 family element RNA-guided endonuclease TnpB | - |
| JMW46_RS16035 (JMW46_16035) | - | 3520480..3522261 (+) | 1782 | WP_003419546.1 | UvrD-helicase domain-containing protein | - |
| JMW46_RS16040 (JMW46_16040) | lepB | 3522341..3522871 (-) | 531 | WP_009905409.1 | signal peptidase I | - |
| JMW46_RS16045 (JMW46_16045) | - | 3522911..3523735 (-) | 825 | WP_009905410.1 | undecaprenyl-diphosphate phosphatase | - |
| JMW46_RS16050 (JMW46_16050) | - | 3523992..3524903 (+) | 912 | WP_022615208.1 | tyrosine-type recombinase/integrase | - |
| JMW46_RS16055 (JMW46_16055) | purB | 3525042..3526487 (+) | 1446 | WP_003419557.1 | adenylosuccinate lyase | - |
| JMW46_RS16060 (JMW46_16060) | - | 3526788..3527240 (+) | 453 | WP_003419561.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
| JMW46_RS16065 (JMW46_16065) | - | 3527459..3528655 (-) | 1197 | WP_003419570.1 | pyridoxal phosphate-dependent aminotransferase | - |
| JMW46_RS16070 (JMW46_16070) | galT | 3529040..3529990 (+) | 951 | WP_003419573.1 | galactose-1-phosphate uridylyltransferase | - |
| JMW46_RS16075 (JMW46_16075) | - | 3530111..3530863 (+) | 753 | WP_003419575.1 | exodeoxyribonuclease III | - |
| JMW46_RS16080 (JMW46_16080) | - | 3530955..3531731 (-) | 777 | WP_003419578.1 | 3'-5' exonuclease | - |
| JMW46_RS16085 (JMW46_16085) | - | 3532046..3533944 (+) | 1899 | WP_003419583.1 | glutamine synthetase | - |
| JMW46_RS16090 (JMW46_16090) | - | 3534072..3535193 (-) | 1122 | WP_003419591.1 | MGDG synthase family glycosyltransferase | - |
| JMW46_RS16095 (JMW46_16095) | - | 3535392..3535724 (+) | 333 | WP_009905416.1 | PadR family transcriptional regulator | - |
| JMW46_RS16100 (JMW46_16100) | - | 3535711..3536769 (+) | 1059 | WP_003419595.1 | DUF1700 domain-containing protein | - |
| JMW46_RS16105 (JMW46_16105) | - | 3536762..3537832 (+) | 1071 | WP_003419596.1 | DUF4097 family beta strand repeat-containing protein | - |
| JMW46_RS16110 (JMW46_16110) | - | 3537934..3538470 (+) | 537 | WP_003419598.1 | hypothetical protein | - |
| JMW46_RS16115 (JMW46_16115) | - | 3538590..3539297 (+) | 708 | WP_009905418.1 | lantibiotic protection ABC transporter ATP-binding protein | - |
| JMW46_RS16120 (JMW46_16120) | - | 3539299..3540018 (+) | 720 | WP_003419603.1 | lantibiotic immunity ABC transporter MutE/EpiE family permease subunit | - |
| JMW46_RS16125 (JMW46_16125) | - | 3540020..3540790 (+) | 771 | WP_003419609.1 | lantibiotic immunity ABC transporter MutG family permease subunit | - |
| JMW46_RS16130 (JMW46_16130) | - | 3540924..3542315 (+) | 1392 | WP_029158131.1 | sensor histidine kinase | - |
| JMW46_RS16135 (JMW46_16135) | - | 3542391..3543212 (-) | 822 | WP_003419615.1 | pyridoxamine kinase | - |
| JMW46_RS16140 (JMW46_16140) | - | 3543463..3544617 (+) | 1155 | WP_009905420.1 | amidase domain-containing protein | - |
| JMW46_RS16145 (JMW46_16145) | - | 3544800..3545000 (+) | 201 | WP_003419624.1 | cold-shock protein | - |
| JMW46_RS16150 (JMW46_16150) | - | 3545421..3545849 (+) | 429 | WP_009889129.1 | CBS domain-containing protein | - |
| JMW46_RS16155 (JMW46_16155) | - | 3545992..3546747 (-) | 756 | WP_009889131.1 | peptidylprolyl isomerase | - |
| JMW46_RS16160 (JMW46_16160) | - | 3547448..3547954 (-) | 507 | WP_003419636.1 | ImmA/IrrE family metallo-endopeptidase | - |
| JMW46_RS16165 (JMW46_16165) | - | 3548036..3548356 (-) | 321 | WP_003419639.1 | XRE family transcriptional regulator | - |
| JMW46_RS16170 (JMW46_16170) | - | 3548525..3548722 (+) | 198 | WP_003419641.1 | helix-turn-helix transcriptional regulator | - |
| JMW46_RS16175 (JMW46_16175) | - | 3548826..3549266 (+) | 441 | WP_003419643.1 | hypothetical protein | - |
| JMW46_RS16180 (JMW46_16180) | - | 3549515..3549958 (+) | 444 | WP_003419644.1 | phage tail terminator family protein | - |
| JMW46_RS16185 (JMW46_16185) | - | 3549963..3551027 (+) | 1065 | WP_003419645.1 | phage tail sheath subtilisin-like domain-containing protein | - |
| JMW46_RS16190 (JMW46_16190) | - | 3551041..3551469 (+) | 429 | WP_003419646.1 | phage tail tube protein | - |
| JMW46_RS16195 (JMW46_16195) | - | 3551583..3552029 (+) | 447 | WP_003419647.1 | phage tail assembly chaperone | - |
| JMW46_RS16200 (JMW46_16200) | - | 3552223..3554676 (+) | 2454 | WP_003419649.1 | hypothetical protein | - |
| JMW46_RS16205 (JMW46_16205) | - | 3554676..3555098 (+) | 423 | WP_003419651.1 | phage baseplate protein | - |
| JMW46_RS16210 (JMW46_16210) | - | 3555380..3556909 (+) | 1530 | WP_202664096.1 | NlpC/P60 family protein | - |
| JMW46_RS16215 (JMW46_16215) | - | 3556925..3557251 (+) | 327 | WP_202664095.1 | DUF2577 family protein | - |
| JMW46_RS16220 (JMW46_16220) | - | 3557251..3557679 (+) | 429 | WP_202664094.1 | DUF2634 domain-containing protein | - |
Sequence
Protein
Download Length: 348 a.a. Molecular weight: 37387.68 Da Isoelectric Point: 4.8236
>NTDB_id=529295 JMW46_RS16010 WP_003419530.1 3512715..3513761(+) (recA) [Clostridioides difficile strain 2016]
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTNEI
DEKVRAFYNLNEEHEEAGNSVSKEIVEE
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTNEI
DEKVRAFYNLNEEHEEAGNSVSKEIVEE
Nucleotide
Download Length: 1047 bp
>NTDB_id=529295 JMW46_RS16010 WP_003419530.1 3512715..3513761(+) (recA) [Clostridioides difficile strain 2016]
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGATATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAGACTACTGTTGCACTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATACGCAAAAGC
TTTGGGCGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGACTCTCACGTAGGGTTACAAGCTAGACTTATGTCGCAAGCTCTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCAGAAACTACTACTGGAGGAC
GTGCATTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGACACAATAAAACAAGGAGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTCGTTAAAAATAAAGTAGCACCTCCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGGATTTCAAAAATTGGAGACCTTCTAGATATAGCTGCTGATGTAGATATAGTAAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAGGATAATTTAGATTTAACTAATGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAAGCAGGTAATTCAGTATCAAAAGAAATTGTAGA
AGAATAA
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGATATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAGACTACTGTTGCACTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATACGCAAAAGC
TTTGGGCGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGACTCTCACGTAGGGTTACAAGCTAGACTTATGTCGCAAGCTCTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCAGAAACTACTACTGGAGGAC
GTGCATTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGACACAATAAAACAAGGAGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTCGTTAAAAATAAAGTAGCACCTCCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGGATTTCAAAAATTGGAGACCTTCTAGATATAGCTGCTGATGTAGATATAGTAAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAGGATAATTTAGATTTAACTAATGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAAGCAGGTAATTCAGTATCAAAAGAAATTGTAGA
AGAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.