Detailed information    

insolico Bioinformatically predicted

Overview


Name   recA   Type   Machinery gene
Locus tag   LC2W_RS05110 Genome accession   NC_017473
Coordinates   998817..999878 (+) Length   353 a.a.
NCBI ID   WP_003598111.1    Uniprot ID   A0A243PT23
Organism   Lacticaseibacillus paracasei     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 970551..1009841 998817..999878 within 0


Gene organization within MGE regions


Location: 970551..1009841
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LC2W_RS04970 (LC2W_0994) - 970551..971549 (-) 999 WP_012490951.1 IS30 family transposase -
  LC2W_RS04975 (LC2W_0995) - 971787..973115 (-) 1329 WP_012491272.1 metallophosphoesterase -
  LC2W_RS04980 (LC2W_0996) - 973306..973572 (+) 267 WP_003564140.1 ACT domain-containing protein -
  LC2W_RS04985 (LC2W_0997) - 973621..974964 (+) 1344 WP_014951764.1 PFL family protein -
  LC2W_RS04990 (LC2W_0998) - 975074..976129 (+) 1056 WP_003569473.1 competence protein CoiA -
  LC2W_RS04995 (LC2W_0999) - 976319..976954 (-) 636 WP_003601677.1 DsbA family protein -
  LC2W_RS05000 (LC2W_1000) - 977024..977617 (-) 594 WP_003601679.1 CYTH domain-containing protein -
  LC2W_RS05005 (LC2W_1001) - 977811..978482 (+) 672 WP_003564145.1 GTP pyrophosphokinase family protein -
  LC2W_RS05010 (LC2W_1002) - 978484..979281 (+) 798 WP_003564146.1 NAD kinase -
  LC2W_RS05015 (LC2W_1003) - 979281..980183 (+) 903 WP_012491275.1 RluA family pseudouridine synthase -
  LC2W_RS05020 (LC2W_1004) - 980292..981350 (-) 1059 WP_012491276.1 FAD:protein FMN transferase -
  LC2W_RS05025 (LC2W_1005) - 981507..982142 (-) 636 WP_003569480.1 copper homeostasis protein CutC -
  LC2W_RS05030 (LC2W_1006) - 982164..982982 (-) 819 WP_014566471.1 undecaprenyl-diphosphate phosphatase -
  LC2W_RS05035 (LC2W_1007) - 983185..984225 (-) 1041 WP_012491278.1 lactonase family protein -
  LC2W_RS05040 (LC2W_1008) - 984497..984874 (+) 378 WP_014566472.1 PTS glucitol/sorbitol transporter subunit IIA -
  LC2W_RS05045 (LC2W_1009) rpsN 984986..985255 (-) 270 WP_003564153.1 30S ribosomal protein S14 -
  LC2W_RS05050 (LC2W_1010) - 985383..986360 (-) 978 WP_024109435.1 GMP reductase -
  LC2W_RS05055 (LC2W_1011) - 986600..987547 (-) 948 WP_003564155.1 magnesium transporter CorA family protein -
  LC2W_RS05060 (LC2W_1012) - 987613..988455 (+) 843 WP_012491280.1 methyltransferase domain-containing protein -
  LC2W_RS05065 (LC2W_1013) trmL 988710..989219 (+) 510 WP_003564157.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
  LC2W_RS05070 (LC2W_1014) - 989346..989756 (+) 411 WP_003564159.1 DUF1149 family protein -
  LC2W_RS05075 (LC2W_1015) - 989929..992250 (+) 2322 WP_003604697.1 FtsK/SpoIIIE family DNA translocase -
  LC2W_RS05080 (LC2W_1016) yfmF 992259..993521 (+) 1263 WP_012491281.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  LC2W_RS05085 (LC2W_1017) yfmH 993518..994810 (+) 1293 WP_014566474.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  LC2W_RS05090 (LC2W_1018) ymfI 994810..995538 (+) 729 WP_003569514.1 elongation factor P 5-aminopentanone reductase -
  LC2W_RS05095 (LC2W_1019) - 995625..996554 (+) 930 WP_003593861.1 helix-turn-helix domain-containing protein -
  LC2W_RS05100 (LC2W_1020) pgsA 996551..997144 (+) 594 WP_003564171.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  LC2W_RS05105 (LC2W_1021) cinA 997519..998760 (+) 1242 WP_012491282.1 competence/damage-inducible protein A Machinery gene
  LC2W_RS05110 (LC2W_1022) recA 998817..999878 (+) 1062 WP_003598111.1 recombinase RecA Machinery gene
  LC2W_RS05115 (LC2W_1023) rny 1000180..1001751 (+) 1572 WP_003657913.1 ribonuclease Y -
  LC2W_RS05120 (LC2W_1024) - 1001845..1002495 (-) 651 WP_012491283.1 YigZ family protein -
  LC2W_RS05125 (LC2W_1025) - 1002523..1003785 (+) 1263 WP_016379935.1 helicase-related protein -
  LC2W_RS05130 (LC2W_1026) - 1003998..1004459 (+) 462 WP_003583965.1 ComF family protein -
  LC2W_RS05135 (LC2W_1027) hpf 1004583..1005140 (+) 558 WP_003569531.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  LC2W_RS05140 (LC2W_1029) secA 1005474..1007837 (+) 2364 WP_003578257.1 preprotein translocase subunit SecA -
  LC2W_RS05145 (LC2W_1030) prfB 1007962..1009078 (+) 1117 WP_096772597.1 peptide chain release factor 2 -
  LC2W_RS05150 (LC2W_1031) ftsE 1009155..1009841 (+) 687 WP_012491286.1 cell division ATP-binding protein FtsE -

Sequence


Protein


Download         Length: 353 a.a.        Molecular weight: 37745.94 Da        Isoelectric Point: 5.8234

>NTDB_id=47424 LC2W_RS05110 WP_003598111.1 998817..999878(+) (recA) [Lacticaseibacillus paracasei]
MAGDERQKALDVALKKIEKNFGKGAIMRMGAKADTRVSVVSSGSLAVDDALGVGGFPRGRIVEIYGPESSGKTTVALHAV
AEVQKQGGTAAYIDAENAMDPKYATALGVNIDELLLSQPDTGEQGLEIADELVASGAIDIVVIDSVAALVPRAEIEGDMG
DAHVGLQARLMSQALRKLSGSINKTKTIALFINQIREKVGIIFGSPETTPGGRALKFYATVRLEIRRSEQIKTGADVVGN
RTKIKVVKNKVAPPFRTAIVDIMYGQGISQTGELVDMAVERDIVEKAGSWYAYQGERIGQGRENAKTYLDNHADLQQTIK
QQVRVAYGMAAAPGRETASVSEDQPEIHQQAEV

Nucleotide


Download         Length: 1062 bp        

>NTDB_id=47424 LC2W_RS05110 WP_003598111.1 998817..999878(+) (recA) [Lacticaseibacillus paracasei]
ATGGCAGGAGACGAACGCCAGAAAGCATTGGATGTTGCACTGAAAAAGATTGAAAAAAATTTTGGTAAAGGCGCGATTAT
GCGAATGGGTGCTAAGGCGGACACGCGCGTTTCCGTTGTCTCTAGCGGCTCACTTGCCGTTGATGATGCACTTGGTGTTG
GGGGCTTTCCGCGCGGACGAATTGTCGAAATTTATGGACCGGAAAGTTCCGGCAAAACAACCGTCGCGCTGCATGCTGTT
GCTGAAGTGCAGAAGCAAGGCGGTACTGCCGCCTATATTGATGCCGAGAATGCGATGGATCCCAAGTACGCAACTGCTTT
GGGCGTCAATATTGACGAATTATTGCTCTCCCAGCCAGACACAGGCGAACAAGGGCTGGAGATTGCTGATGAACTAGTCG
CGTCTGGTGCCATTGATATTGTGGTGATTGATTCAGTTGCTGCTTTGGTGCCGCGGGCTGAGATTGAGGGCGATATGGGG
GATGCCCATGTTGGCTTGCAAGCCCGATTAATGTCACAGGCGTTACGTAAGTTATCCGGTTCCATCAATAAGACAAAAAC
GATTGCTTTATTCATTAATCAGATTCGTGAGAAAGTCGGGATCATTTTTGGGAGTCCGGAAACGACACCAGGTGGTCGCG
CATTGAAGTTTTATGCGACTGTTCGGTTAGAAATCCGGCGGTCGGAACAGATCAAGACAGGCGCAGATGTCGTCGGCAAT
CGCACTAAAATCAAAGTGGTCAAGAATAAGGTGGCACCGCCTTTTCGAACAGCAATTGTGGATATCATGTATGGCCAAGG
CATTTCGCAAACTGGCGAACTTGTCGACATGGCCGTTGAGAGAGATATTGTTGAAAAAGCAGGGTCATGGTACGCGTATC
AAGGTGAACGCATCGGCCAAGGTCGCGAAAACGCTAAGACATATCTTGATAACCACGCTGATCTTCAGCAGACGATTAAA
CAACAGGTTCGCGTGGCTTATGGTATGGCAGCCGCACCTGGTCGGGAGACGGCTTCGGTCAGTGAAGATCAACCCGAAAT
ACATCAACAGGCTGAAGTATGA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A243PT23

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recA Latilactobacillus sakei subsp. sakei 23K

78.963

98.3

0.776

  recA Bacillus subtilis subsp. subtilis str. 168

74.154

92.068

0.683

  recA Streptococcus mutans UA159

67.919

98.017

0.666

  recA Streptococcus mitis SK321

67.919

98.017

0.666

  recA Streptococcus mitis NCTC 12261

67.919

98.017

0.666

  recA Streptococcus pyogenes NZ131

70.606

93.484

0.66

  recA Streptococcus pneumoniae Rx1

69.486

93.768

0.652

  recA Streptococcus pneumoniae D39

69.486

93.768

0.652

  recA Streptococcus pneumoniae R6

69.486

93.768

0.652

  recA Streptococcus pneumoniae TIGR4

69.486

93.768

0.652

  recA Lactococcus lactis subsp. cremoris KW2

68.882

93.768

0.646

  recA Ralstonia pseudosolanacearum GMI1000

65.495

88.669

0.581

  recA Neisseria gonorrhoeae MS11

62.385

92.635

0.578

  recA Neisseria gonorrhoeae MS11

62.385

92.635

0.578

  recA Neisseria gonorrhoeae strain FA1090

62.385

92.635

0.578

  recA Acinetobacter baylyi ADP1

58.43

97.45

0.569

  recA Pseudomonas stutzeri DSM 10701

58.529

96.317

0.564

  recA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

61.3

91.501

0.561

  recA Acinetobacter baumannii D1279779

61.059

90.935

0.555

  recA Glaesserella parasuis strain SC1401

54.83

99.717

0.547

  recA Riemerella anatipestifer ATCC 11845 = DSM 15868

59.021

92.635

0.547

  recA Helicobacter pylori 26695

58.182

93.484

0.544

  recA Helicobacter pylori strain NCTC11637

58.182

93.484

0.544

  recA Vibrio cholerae O1 biovar El Tor strain E7946

59.19

90.935

0.538

  recA Vibrio cholerae strain A1552

59.19

90.935

0.538

  recA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.269

92.635

0.521


Multiple sequence alignment