Detailed information NTG0431345

Bioinformatically predicted

Overview

• Name: comFA
• Type: Machinery gene
• Locus tag: ILP75_RS12010
• Genome accession: NZ_CP062471
• Coordinates: 2462373..2463455 (+)
• Length: 360 a.a.
• NCBI ID: WP_001548033.1
• Uniprot ID: A0A0H2XJ41
• Organism: Staphylococcus aureus strain MRSA - AMRF 3
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2457373..2468455

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ILP75_RS11990 (ILP75_11990)	gdpS	2457745..2458815 (-)	1071	WP_000460983.1	GGDEF domain-containing protein GdpS	-
ILP75_RS11995 (ILP75_11995)	-	2459133..2460188 (+)	1056	WP_000258151.1	glycosyltransferase family 4 protein	-
ILP75_RS12000 (ILP75_12000)	-	2460358..2460999 (-)	642	WP_000192947.1	YigZ family protein	-
ILP75_RS12005 (ILP75_12005)	fakB1	2461143..2462009 (+)	867	WP_000686342.1	fatty acid kinase binding subunit FakB1	-
ILP75_RS12010 (ILP75_12010)	comFA	2462373..2463455 (+)	1083	WP_001548033.1	DEAD/DEAH box helicase	Machinery gene
ILP75_RS12015 (ILP75_12015)	-	2463448..2464122 (+)	675	WP_001057965.1	ComF family protein	-
ILP75_RS12020 (ILP75_12020)	hpf	2464183..2464755 (+)	573	WP_000617735.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
ILP75_RS12025 (ILP75_12025)	secA	2465169..2467700 (+)	2532	WP_000506531.1	preprotein translocase subunit SecA	-
ILP75_RS12030 (ILP75_12030)	-	2467742..2467846 (+)	105	WP_001790092.1	hypothetical protein	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 42111.65 Da
• Isoelectric Point: 9.8307

>NTDB_id=431345 ILP75_RS12010 WP_001548033.1 2462373..2463455(+) (comFA) [Staphylococcus aureus strain MRSA - AMRF 3]
MDNVTRYKITESSQSSSQAYYHLSFELSEQQSYASEHIVRAIRKRQTILLYAVTGAGKTEMMFQGIQYARIQGDNIAIVS
PRVDVVVEISKRIKDAFLNEDIDILHQQSRQQFEGHFVVCTVHQLYRFKQHFDTIFIDEVDAFPLSMDKNLQQALKSSSK
VEHATIYMTATPPKQLLSEIPHENIIKLPARFHKKSLPVPKYRYFKLNNKKIQKMLYRILQDQINNQRYTLVFFNNIETM
IKTFSVYKQKITKLTYVHSEDVFRFEKVEQLRNGHFDVIFTTTILERGFTMANLDVVVIDAHQYTQEALIQIAGRVGRKL
ECPTGKVLFFHEGVSMNMIQAKKEIQRMNKLALKRGWIDE

Nucleotide

• Length: 1083 bp

>NTDB_id=431345 ILP75_RS12010 WP_001548033.1 2462373..2463455(+) (comFA) [Staphylococcus aureus strain MRSA - AMRF 3]
ATGGATAATGTAACAAGATATAAAATAACAGAGAGTTCGCAAAGTTCATCACAAGCATATTATCATCTCTCATTTGAATT
GTCGGAACAGCAGTCTTATGCCTCAGAACATATTGTTCGAGCCATTAGAAAGAGACAAACGATTTTGTTATATGCCGTAA
CAGGTGCAGGTAAGACAGAAATGATGTTTCAAGGCATTCAATATGCAAGAATACAGGGAGATAATATAGCTATTGTGTCA
CCACGTGTAGATGTTGTTGTAGAAATTAGTAAACGTATTAAAGACGCATTTCTTAATGAAGATATAGACATACTACACCA
GCAATCAAGACAACAATTTGAAGGGCATTTTGTTGTATGCACAGTGCATCAACTTTACCGATTCAAACAGCACTTTGATA
CTATTTTTATTGATGAAGTCGATGCCTTTCCTTTATCAATGGATAAAAATCTACAACAAGCATTGAAGTCATCTTCTAAA
GTTGAACATGCAACAATTTATATGACAGCAACACCACCGAAACAACTTCTGTCAGAGATTCCCCACGAAAATATAATTAA
ATTGCCAGCTCGCTTTCATAAAAAATCACTTCCAGTTCCTAAATATCGTTATTTCAAACTTAATAATAAGAAGATTCAGA
AAATGTTATACCGAATTTTACAAGATCAAATTAATAATCAACGTTATACACTGGTGTTTTTTAACAATATAGAAACAATG
ATTAAAACATTTTCGGTTTATAAGCAGAAAATTACTAAATTAACATACGTCCATAGCGAGGATGTTTTTCGCTTTGAAAA
AGTTGAACAATTAAGGAATGGACATTTCGATGTCATTTTTACTACGACAATATTAGAACGTGGATTTACAATGGCAAATT
TGGATGTTGTTGTTATCGATGCACATCAATATACTCAAGAGGCTTTAATACAAATTGCTGGACGTGTTGGACGAAAATTA
GAATGTCCTACTGGAAAAGTATTGTTTTTTCATGAAGGGGTAAGTATGAATATGATTCAAGCTAAAAAAGAGATTCAAAG
GATGAACAAATTAGCATTAAAAAGAGGTTGGATTGATGAATAA

Domains

Predicted by InterProScan.

• Helicase conserved C-terminal domain (Helicase_C) (215-318)

• Type III restriction enzyme, res subunit (ResIII) (25-173)

3D structure

• AlphaFold DB: A0A0H2XJ41

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA	Bacillus subtilis subsp. subtilis str. 168	38.938	94.167	0.367