Detailed information
Bioinformatically predicted
Overview
| Name | recA | Type | Machinery gene |
| Locus tag | FTB24_RS12375 | Genome accession | NZ_CP045224 |
| Coordinates | 2702927..2703973 (-) | Length | 348 a.a. |
| NCBI ID | WP_003419530.1 | Uniprot ID | A0AAX3GVV5 |
| Organism | Clostridioides difficile strain TW11 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 2661317..2728837 | 2702927..2703973 | within | 0 |
Gene organization within MGE regions
Location: 2661317..2728837
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FTB24_RS12165 (FTB24_12160) | - | 2661590..2662012 (-) | 423 | WP_003419651.1 | phage baseplate protein | - |
| FTB24_RS12170 (FTB24_12165) | - | 2662012..2664465 (-) | 2454 | WP_003419649.1 | hypothetical protein | - |
| FTB24_RS12180 (FTB24_12175) | - | 2664659..2665105 (-) | 447 | WP_003419647.1 | phage tail assembly chaperone | - |
| FTB24_RS12185 (FTB24_12180) | - | 2665219..2665647 (-) | 429 | WP_003419646.1 | phage tail tube protein | - |
| FTB24_RS12190 (FTB24_12185) | - | 2665661..2666725 (-) | 1065 | WP_003419645.1 | phage tail sheath subtilisin-like domain-containing protein | - |
| FTB24_RS12195 (FTB24_12190) | - | 2666730..2667173 (-) | 444 | WP_003419644.1 | phage tail terminator family protein | - |
| FTB24_RS12200 (FTB24_12195) | - | 2667422..2667862 (-) | 441 | WP_003419643.1 | hypothetical protein | - |
| FTB24_RS12205 (FTB24_12200) | - | 2667966..2668163 (-) | 198 | WP_003419641.1 | helix-turn-helix transcriptional regulator | - |
| FTB24_RS12210 (FTB24_12205) | - | 2668332..2668652 (+) | 321 | WP_003419639.1 | XRE family transcriptional regulator | - |
| FTB24_RS12215 (FTB24_12210) | - | 2668734..2669240 (+) | 507 | WP_003419636.1 | ImmA/IrrE family metallo-endopeptidase | - |
| FTB24_RS12225 (FTB24_12220) | - | 2669941..2670696 (+) | 756 | WP_009889131.1 | peptidylprolyl isomerase | - |
| FTB24_RS12230 (FTB24_12225) | - | 2670839..2671267 (-) | 429 | WP_009889129.1 | CBS domain-containing protein | - |
| FTB24_RS12235 (FTB24_12230) | - | 2671688..2671888 (-) | 201 | WP_003419624.1 | cold-shock protein | - |
| FTB24_RS12240 (FTB24_12235) | - | 2672071..2673225 (-) | 1155 | WP_009905420.1 | amidase domain-containing protein | - |
| FTB24_RS12245 (FTB24_12240) | - | 2673476..2674297 (+) | 822 | WP_003419615.1 | pyridoxamine kinase | - |
| FTB24_RS12250 (FTB24_12245) | - | 2674373..2675764 (-) | 1392 | WP_029158131.1 | sensor histidine kinase | - |
| FTB24_RS12255 (FTB24_12250) | - | 2675898..2676668 (-) | 771 | WP_003419609.1 | lantibiotic immunity ABC transporter MutG family permease subunit | - |
| FTB24_RS12260 (FTB24_12255) | - | 2676670..2677389 (-) | 720 | WP_003419603.1 | lantibiotic immunity ABC transporter MutE/EpiE family permease subunit | - |
| FTB24_RS12265 (FTB24_12260) | - | 2677391..2678098 (-) | 708 | WP_009905418.1 | lantibiotic protection ABC transporter ATP-binding protein | - |
| FTB24_RS12270 (FTB24_12265) | - | 2678218..2678754 (-) | 537 | WP_003419598.1 | hypothetical protein | - |
| FTB24_RS12275 (FTB24_12270) | - | 2678856..2679926 (-) | 1071 | WP_003419596.1 | DUF4097 family beta strand repeat-containing protein | - |
| FTB24_RS12280 (FTB24_12275) | - | 2679919..2680977 (-) | 1059 | WP_003419595.1 | DUF1700 domain-containing protein | - |
| FTB24_RS12285 (FTB24_12280) | - | 2680964..2681296 (-) | 333 | WP_009905416.1 | PadR family transcriptional regulator | - |
| FTB24_RS12290 (FTB24_12285) | - | 2681495..2682616 (+) | 1122 | WP_003419591.1 | MGDG synthase family glycosyltransferase | - |
| FTB24_RS12295 (FTB24_12290) | - | 2682744..2684642 (-) | 1899 | WP_003419583.1 | glutamine synthetase | - |
| FTB24_RS12300 (FTB24_12295) | - | 2684957..2685733 (+) | 777 | WP_003419578.1 | 3'-5' exonuclease | - |
| FTB24_RS12305 (FTB24_12300) | - | 2685825..2686577 (-) | 753 | WP_003419575.1 | exodeoxyribonuclease III | - |
| FTB24_RS12310 (FTB24_12305) | galT | 2686698..2687648 (-) | 951 | WP_003419573.1 | galactose-1-phosphate uridylyltransferase | - |
| FTB24_RS12315 (FTB24_12310) | - | 2688033..2689229 (+) | 1197 | WP_003419570.1 | pyridoxal phosphate-dependent aminotransferase | - |
| FTB24_RS12320 (FTB24_12315) | - | 2689448..2689900 (-) | 453 | WP_003419561.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
| FTB24_RS12325 (FTB24_12320) | purB | 2690201..2691646 (-) | 1446 | WP_003419557.1 | adenylosuccinate lyase | - |
| FTB24_RS12330 (FTB24_12325) | - | 2691785..2692696 (-) | 912 | WP_022615208.1 | tyrosine-type recombinase/integrase | - |
| FTB24_RS12335 (FTB24_12330) | - | 2692953..2693777 (+) | 825 | WP_009905410.1 | undecaprenyl-diphosphate phosphatase | - |
| FTB24_RS12340 (FTB24_12335) | lepB | 2693817..2694347 (+) | 531 | WP_009905409.1 | signal peptidase I | - |
| FTB24_RS12345 (FTB24_12340) | - | 2694427..2696208 (-) | 1782 | WP_003419546.1 | UvrD-helicase domain-containing protein | - |
| FTB24_RS12350 (FTB24_12345) | tnpB | 2696540..2697658 (-) | 1119 | WP_041160402.1 | IS200/IS605 family element RNA-guided endonuclease TnpB | - |
| FTB24_RS12355 (FTB24_12350) | - | 2697660..2697758 (-) | 99 | Protein_2417 | transposase | - |
| FTB24_RS12365 (FTB24_12360) | - | 2698564..2700900 (-) | 2337 | WP_003419542.1 | diguanylate cyclase | - |
| FTB24_RS12370 (FTB24_12365) | rny | 2701210..2702751 (-) | 1542 | WP_003428216.1 | ribonuclease Y | - |
| FTB24_RS12375 (FTB24_12370) | recA | 2702927..2703973 (-) | 1047 | WP_003419530.1 | recombinase RecA | Machinery gene |
| FTB24_RS12380 (FTB24_12375) | pgsA | 2704240..2704782 (-) | 543 | WP_009905407.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase | - |
| FTB24_RS12385 (FTB24_12380) | rimO | 2704769..2706103 (-) | 1335 | WP_003419527.1 | 30S ribosomal protein S12 methylthiotransferase RimO | - |
| FTB24_RS12390 (FTB24_12385) | mnmH | 2706097..2707155 (-) | 1059 | WP_003419524.1 | tRNA 2-selenouridine(34) synthase MnmH | - |
| FTB24_RS12395 (FTB24_12390) | - | 2707158..2709566 (-) | 2409 | WP_003419521.1 | FtsK/SpoIIIE family DNA translocase | - |
| FTB24_RS12400 (FTB24_12395) | - | 2709689..2710423 (-) | 735 | WP_009905406.1 | ClpP family protease | - |
| FTB24_RS12405 (FTB24_12400) | dapG | 2710537..2711760 (-) | 1224 | WP_003419506.1 | aspartate kinase | - |
| FTB24_RS12410 (FTB24_12405) | - | 2711770..2712015 (-) | 246 | WP_003419503.1 | YlmC/YmxH family sporulation protein | - |
| FTB24_RS12415 (FTB24_12410) | - | 2712050..2713297 (-) | 1248 | WP_003419500.1 | M16 family metallopeptidase | - |
| FTB24_RS12420 (FTB24_12415) | - | 2713455..2714198 (-) | 744 | WP_003419498.1 | polysaccharide deacetylase family protein | - |
| FTB24_RS12425 (FTB24_12420) | pnp | 2714321..2716432 (-) | 2112 | WP_003419494.1 | polyribonucleotide nucleotidyltransferase | - |
| FTB24_RS12430 (FTB24_12425) | - | 2716557..2717402 (-) | 846 | WP_003419493.1 | DegV family protein | - |
| FTB24_RS12435 (FTB24_12430) | rpsO | 2717642..2717899 (-) | 258 | WP_003419491.1 | 30S ribosomal protein S15 | - |
| FTB24_RS12445 (FTB24_12440) | - | 2718003..2718932 (-) | 930 | WP_003419488.1 | bifunctional riboflavin kinase/FAD synthetase | - |
| FTB24_RS12450 (FTB24_12445) | truB | 2719062..2719967 (-) | 906 | WP_003419486.1 | tRNA pseudouridine(55) synthase TruB | - |
| FTB24_RS12455 (FTB24_12450) | - | 2719980..2720963 (-) | 984 | WP_003419484.1 | DHH family phosphoesterase | - |
| FTB24_RS12460 (FTB24_12455) | rbfA | 2720944..2721324 (-) | 381 | WP_003419483.1 | 30S ribosome-binding factor RbfA | - |
| FTB24_RS12465 (FTB24_12460) | infB | 2721367..2723307 (-) | 1941 | WP_003419480.1 | translation initiation factor IF-2 | - |
| FTB24_RS12470 (FTB24_12465) | - | 2723329..2723640 (-) | 312 | WP_003419470.1 | L7Ae/L30e/S12e/Gadd45 family ribosomal protein | - |
| FTB24_RS12475 (FTB24_12470) | rnpM | 2723630..2723911 (-) | 282 | WP_003419469.1 | RNase P modulator RnpM | - |
| FTB24_RS12480 (FTB24_12475) | nusA | 2723918..2725072 (-) | 1155 | WP_003419468.1 | transcription termination factor NusA | - |
| FTB24_RS12485 (FTB24_12480) | rimP | 2725102..2725563 (-) | 462 | WP_003419467.1 | ribosome maturation factor RimP | - |
Sequence
Protein
Download Length: 348 a.a. Molecular weight: 37387.68 Da Isoelectric Point: 4.8236
>NTDB_id=392822 FTB24_RS12375 WP_003419530.1 2702927..2703973(-) (recA) [Clostridioides difficile strain TW11]
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTNEI
DEKVRAFYNLNEEHEEAGNSVSKEIVEE
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTNEI
DEKVRAFYNLNEEHEEAGNSVSKEIVEE
Nucleotide
Download Length: 1047 bp
>NTDB_id=392822 FTB24_RS12375 WP_003419530.1 2702927..2703973(-) (recA) [Clostridioides difficile strain TW11]
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGATATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAGACTACTGTTGCACTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATACGCAAAAGC
TTTGGGCGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGACTCTCACGTAGGGTTACAAGCTAGACTTATGTCGCAAGCTCTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCAGAAACTACTACTGGAGGAC
GTGCATTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGACACAATAAAACAAGGAGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTCGTTAAAAATAAAGTAGCACCTCCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGGATTTCAAAAATTGGAGACCTTCTAGATATAGCTGCTGATGTAGATATAGTAAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAGGATAATTTAGATTTAACTAATGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAAGCAGGTAATTCAGTATCAAAAGAAATTGTAGA
AGAATAA
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGATATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAGACTACTGTTGCACTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATACGCAAAAGC
TTTGGGCGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGACTCTCACGTAGGGTTACAAGCTAGACTTATGTCGCAAGCTCTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCAGAAACTACTACTGGAGGAC
GTGCATTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGACACAATAAAACAAGGAGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTCGTTAAAAATAAAGTAGCACCTCCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGGATTTCAAAAATTGGAGACCTTCTAGATATAGCTGCTGATGTAGATATAGTAAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAGGATAATTTAGATTTAACTAATGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAAGCAGGTAATTCAGTATCAAAAGAAATTGTAGA
AGAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.