Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   HKW69_RS11300 Genome accession   NZ_CP053080
Coordinates   2399327..2399983 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain HB37     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2394327..2404983
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HKW69_RS11270 (HKW69_11285) dcyD 2395206..2396192 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  HKW69_RS11275 (HKW69_11290) tcyL 2396207..2396875 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  HKW69_RS11280 (HKW69_11295) tcyN 2396872..2397624 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  HKW69_RS11285 (HKW69_11300) sdiA 2397854..2398576 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  HKW69_RS11290 (HKW69_11305) yecF 2398644..2398868 (-) 225 WP_000106480.1 DUF2594 family protein YecF -
  HKW69_RS11295 (HKW69_11310) yecU 2398855..2399031 (-) 177 WP_001307856.1 protein YecU -
  HKW69_RS11300 (HKW69_11315) letA 2399327..2399983 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  HKW69_RS11305 (HKW69_11320) uvrC 2399980..2401812 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  HKW69_RS11310 (HKW69_11325) pgsA 2401869..2402417 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  HKW69_RS11330 (HKW69_11345) yecA 2403066..2403731 (+) 666 WP_000847886.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=389730 HKW69_RS11300 WP_000611328.1 2399327..2399983(+) (letA) [Escherichia coli strain HB37]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=389730 HKW69_RS11300 WP_000611328.1 2399327..2399983(+) (letA) [Escherichia coli strain HB37]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment