Detailed information NTG0037266

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: SAT0131_RS06425
• Genome accession: NC_017347
• Coordinates: 1290130..1290903 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus subsp. aureus T0131
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1285130..1295903

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAT0131_RS06405 (SAT0131_01302)	trmFO	1285474..1286781 (+)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
SAT0131_RS06410 (SAT0131_01303)	xerC	1287198..1288094 (+)	897	WP_001015597.1	tyrosine recombinase XerC	-
SAT0131_RS06415 (SAT0131_01304)	hslV	1288091..1288636 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
SAT0131_RS06420 (SAT0131_01305)	hslU	1288702..1290105 (+)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
SAT0131_RS06425 (SAT0131_01307)	codY	1290130..1290903 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
SAT0131_RS06430	-	1290954..1291046 (+)	93	WP_001790530.1	hypothetical protein	-
SAT0131_RS06435 (SAT0131_01308)	rpsB	1291245..1292012 (+)	768	WP_000268484.1	30S ribosomal protein S2	-
SAT0131_RS06440	-	1292046..1292159 (+)	114	WP_001789890.1	hypothetical protein	-
SAT0131_RS06445 (SAT0131_01310)	tsf	1292194..1293075 (+)	882	WP_000201387.1	translation elongation factor Ts	-
SAT0131_RS06450 (SAT0131_01311)	pyrH	1293212..1293934 (+)	723	WP_000057330.1	UMP kinase	-
SAT0131_RS06455 (SAT0131_01312)	frr	1293953..1294507 (+)	555	WP_001280006.1	ribosome recycling factor	-
SAT0131_RS06460 (SAT0131_01313)	-	1294880..1295650 (+)	771	WP_000473701.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=37266 SAT0131_RS06425 WP_000055337.1 1290130..1290903(+) (codY) [Staphylococcus aureus subsp. aureus T0131]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=37266 SAT0131_RS06425 WP_000055337.1 1290130..1290903(+) (codY) [Staphylococcus aureus subsp. aureus T0131]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGGGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428