Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   GKC13_RS02950 Genome accession   NZ_CP046134
Coordinates   557616..558260 (+) Length   214 a.a.
NCBI ID   WP_207559816.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain MAG_rmk202_sterm     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 552616..563260
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GKC13_RS02930 (GKC13_02940) stkP/pknB 552993..554864 (+) 1872 WP_014727614.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  GKC13_RS09890 - 555499..555666 (+) 168 WP_014727613.1 potassium channel family protein -
  GKC13_RS02940 (GKC13_02950) liaF 555921..556619 (+) 699 WP_014621793.1 cell wall-active antibiotics response protein LiaF -
  GKC13_RS02945 (GKC13_02955) - 556616..557626 (+) 1011 WP_180479473.1 sensor histidine kinase -
  GKC13_RS02950 (GKC13_02960) vraR 557616..558260 (+) 645 WP_207559816.1 response regulator transcription factor Regulator
  GKC13_RS02965 (GKC13_02975) rimM 558930..559448 (+) 519 WP_011681402.1 ribosome maturation factor RimM -
  GKC13_RS02970 (GKC13_02980) trmD 559438..560157 (+) 720 WP_207559815.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  GKC13_RS02975 (GKC13_02985) - 560159..561157 (+) 999 WP_207559814.1 NAD(P)/FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24074.42 Da        Isoelectric Point: 4.5222

>NTDB_id=350164 GKC13_RS02950 WP_207559816.1 557616..558260(+) (vraR) [Streptococcus thermophilus strain MAG_rmk202_sterm]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSYPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=350164 GKC13_RS02950 WP_207559816.1 557616..558260(+) (vraR) [Streptococcus thermophilus strain MAG_rmk202_sterm]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGACCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTCAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGATAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCACGATAGTTACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.818

100

0.379

Multiple sequence alignment