Detailed information
Bioinformatically predicted
Overview
| Name | recA | Type | Machinery gene |
| Locus tag | E1H35_RS06645 | Genome accession | NZ_CP037821 |
| Coordinates | 1424019..1425065 (+) | Length | 348 a.a. |
| NCBI ID | WP_003428218.1 | Uniprot ID | A0A031WFI0 |
| Organism | Clostridioides difficile strain Cd12 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1395647..1472859 | 1424019..1425065 | within | 0 |
Gene organization within MGE regions
Location: 1395647..1472859
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E1H35_RS06530 (E1H35_06680) | acd | 1395722..1397545 (+) | 1824 | WP_003438294.1 | N-acetylglucosaminidase | - |
| E1H35_RS06535 (E1H35_06685) | - | 1397760..1402058 (+) | 4299 | WP_003438301.1 | PolC-type DNA polymerase III | - |
| E1H35_RS06540 (E1H35_06690) | rimP | 1402262..1402723 (+) | 462 | WP_003438303.1 | ribosome maturation factor RimP | - |
| E1H35_RS06545 (E1H35_06695) | nusA | 1402753..1403907 (+) | 1155 | WP_003428238.1 | transcription termination factor NusA | - |
| E1H35_RS06550 (E1H35_06700) | rnpM | 1403914..1404195 (+) | 282 | WP_003419469.1 | RNase P modulator RnpM | - |
| E1H35_RS06555 (E1H35_06705) | - | 1404185..1404496 (+) | 312 | WP_003419470.1 | L7Ae/L30e/S12e/Gadd45 family ribosomal protein | - |
| E1H35_RS06560 (E1H35_06710) | infB | 1404518..1406458 (+) | 1941 | WP_003438306.1 | translation initiation factor IF-2 | - |
| E1H35_RS06565 (E1H35_06715) | rbfA | 1406501..1406881 (+) | 381 | WP_003428234.1 | 30S ribosome-binding factor RbfA | - |
| E1H35_RS06570 (E1H35_06720) | - | 1406862..1407845 (+) | 984 | WP_003438308.1 | DHH family phosphoesterase | - |
| E1H35_RS06575 (E1H35_06725) | truB | 1407858..1408763 (+) | 906 | WP_003428232.1 | tRNA pseudouridine(55) synthase TruB | - |
| E1H35_RS06580 (E1H35_06730) | - | 1408894..1409823 (+) | 930 | WP_003438310.1 | bifunctional riboflavin kinase/FAD synthetase | - |
| E1H35_RS06585 (E1H35_06740) | rpsO | 1409927..1410184 (+) | 258 | WP_003419491.1 | 30S ribosomal protein S15 | - |
| E1H35_RS06590 (E1H35_06745) | - | 1410424..1411269 (+) | 846 | WP_009889099.1 | DegV family protein | - |
| E1H35_RS06595 (E1H35_06750) | pnp | 1411394..1413505 (+) | 2112 | WP_003438316.1 | polyribonucleotide nucleotidyltransferase | - |
| E1H35_RS06600 (E1H35_06755) | - | 1413771..1414514 (+) | 744 | WP_003438319.1 | polysaccharide deacetylase family protein | - |
| E1H35_RS06605 (E1H35_06760) | - | 1414672..1415919 (+) | 1248 | WP_003438321.1 | M16 family metallopeptidase | - |
| E1H35_RS06610 (E1H35_06765) | - | 1415954..1416199 (+) | 246 | WP_003419503.1 | YlmC/YmxH family sporulation protein | - |
| E1H35_RS06615 (E1H35_06770) | dapG | 1416209..1417432 (+) | 1224 | WP_003438324.1 | aspartate kinase | - |
| E1H35_RS06620 (E1H35_06775) | - | 1417545..1418279 (+) | 735 | WP_003428224.1 | ClpP family protease | - |
| E1H35_RS06625 (E1H35_06780) | - | 1418402..1420813 (+) | 2412 | WP_003438328.1 | FtsK/SpoIIIE family DNA translocase | - |
| E1H35_RS06630 (E1H35_06785) | mnmH | 1420816..1421874 (+) | 1059 | WP_003438330.1 | tRNA 2-selenouridine(34) synthase MnmH | - |
| E1H35_RS06635 (E1H35_06790) | rimO | 1421868..1423202 (+) | 1335 | WP_003438333.1 | 30S ribosomal protein S12 methylthiotransferase RimO | - |
| E1H35_RS06640 (E1H35_06795) | pgsA | 1423189..1423731 (+) | 543 | WP_021370268.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase | - |
| E1H35_RS06645 (E1H35_06800) | recA | 1424019..1425065 (+) | 1047 | WP_003428218.1 | recombinase RecA | Machinery gene |
| E1H35_RS06650 (E1H35_06805) | rny | 1425241..1426782 (+) | 1542 | WP_003428216.1 | ribonuclease Y | - |
| E1H35_RS06655 (E1H35_06810) | - | 1427096..1429432 (+) | 2337 | WP_003438341.1 | diguanylate cyclase | - |
| E1H35_RS06660 (E1H35_06815) | - | 1429814..1431595 (+) | 1782 | WP_003438344.1 | UvrD-helicase domain-containing protein | - |
| E1H35_RS06665 (E1H35_06820) | lepB | 1431677..1432207 (-) | 531 | WP_009902411.1 | signal peptidase I | - |
| E1H35_RS06670 (E1H35_06825) | - | 1432247..1433071 (-) | 825 | WP_003438350.1 | undecaprenyl-diphosphate phosphatase | - |
| E1H35_RS06675 (E1H35_06830) | - | 1433328..1434236 (+) | 909 | WP_009889110.1 | tyrosine-type recombinase/integrase | - |
| E1H35_RS06680 (E1H35_06835) | purB | 1434380..1435825 (+) | 1446 | WP_003438353.1 | adenylosuccinate lyase | - |
| E1H35_RS06685 (E1H35_06840) | - | 1436136..1436588 (+) | 453 | WP_003419561.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
| E1H35_RS06690 (E1H35_06845) | - | 1436923..1438119 (-) | 1197 | WP_003438357.1 | pyridoxal phosphate-dependent aminotransferase | - |
| E1H35_RS06695 (E1H35_06850) | galT | 1438504..1439454 (+) | 951 | WP_003438360.1 | galactose-1-phosphate uridylyltransferase | - |
| E1H35_RS06700 (E1H35_06855) | - | 1439615..1440367 (+) | 753 | WP_003438367.1 | exodeoxyribonuclease III | - |
| E1H35_RS06705 (E1H35_06860) | - | 1440459..1441235 (-) | 777 | WP_003438370.1 | 3'-5' exonuclease | - |
| E1H35_RS06710 (E1H35_06865) | - | 1441550..1443448 (+) | 1899 | WP_003428202.1 | glutamine synthetase | - |
| E1H35_RS06715 (E1H35_06870) | - | 1443576..1444697 (-) | 1122 | WP_003438374.1 | MGDG synthase family glycosyltransferase | - |
| E1H35_RS06720 (E1H35_06875) | - | 1444896..1445228 (+) | 333 | WP_009889116.1 | PadR family transcriptional regulator | - |
| E1H35_RS06725 (E1H35_06880) | - | 1445215..1446273 (+) | 1059 | WP_003438377.1 | DUF1700 domain-containing protein | - |
| E1H35_RS06730 (E1H35_06885) | - | 1446266..1447336 (+) | 1071 | WP_003438380.1 | DUF4097 family beta strand repeat-containing protein | - |
| E1H35_RS06735 (E1H35_06890) | - | 1447438..1447974 (+) | 537 | WP_003428196.1 | lipoprotein | - |
| E1H35_RS06740 (E1H35_06895) | - | 1448090..1448797 (+) | 708 | WP_016729592.1 | lantibiotic protection ABC transporter ATP-binding protein | - |
| E1H35_RS06745 (E1H35_06900) | - | 1448799..1449515 (+) | 717 | WP_003438387.1 | lantibiotic immunity ABC transporter MutE/EpiE family permease subunit | - |
| E1H35_RS06750 (E1H35_06905) | - | 1449517..1450275 (+) | 759 | WP_021363441.1 | lantibiotic immunity ABC transporter MutG family permease subunit | - |
| E1H35_RS06755 (E1H35_06910) | - | 1450410..1451798 (+) | 1389 | WP_021368953.1 | two-component system sensor histidine kinase | - |
| E1H35_RS06760 (E1H35_06915) | - | 1451874..1452695 (-) | 822 | WP_003438396.1 | pyridoxamine kinase | - |
| E1H35_RS06765 (E1H35_06920) | - | 1452946..1454100 (+) | 1155 | WP_009902426.1 | amidase domain-containing protein | - |
| E1H35_RS06770 (E1H35_06925) | - | 1454283..1454483 (+) | 201 | WP_003419624.1 | cold-shock protein | - |
| E1H35_RS06775 (E1H35_06930) | - | 1454904..1455332 (+) | 429 | WP_009889129.1 | CBS domain-containing protein | - |
| E1H35_RS06780 (E1H35_06935) | - | 1455475..1456230 (-) | 756 | WP_009889131.1 | peptidylprolyl isomerase | - |
| E1H35_RS06785 (E1H35_06945) | - | 1456931..1457437 (-) | 507 | WP_003428186.1 | ImmA/IrrE family metallo-endopeptidase | - |
| E1H35_RS06790 (E1H35_06950) | - | 1457519..1457839 (-) | 321 | WP_003428185.1 | XRE family transcriptional regulator | - |
| E1H35_RS06795 (E1H35_06955) | - | 1458008..1458205 (+) | 198 | WP_003419641.1 | helix-turn-helix transcriptional regulator | - |
| E1H35_RS06800 (E1H35_06960) | - | 1458310..1458750 (+) | 441 | WP_003428183.1 | hypothetical protein | - |
| E1H35_RS06805 (E1H35_06965) | - | 1458999..1459442 (+) | 444 | WP_003438413.1 | phage tail terminator family protein | - |
| E1H35_RS06810 (E1H35_06970) | - | 1459447..1460511 (+) | 1065 | WP_003438414.1 | phage tail sheath subtilisin-like domain-containing protein | - |
| E1H35_RS06815 (E1H35_06975) | - | 1460525..1460953 (+) | 429 | WP_003419646.1 | phage tail tube protein | - |
| E1H35_RS06820 (E1H35_06980) | - | 1461067..1461513 (+) | 447 | WP_003419647.1 | phage tail assembly chaperone | - |
| E1H35_RS06825 (E1H35_06985) | - | 1461540..1461707 (+) | 168 | WP_003419648.1 | hypothetical protein | - |
| E1H35_RS06830 (E1H35_06990) | - | 1461707..1464160 (+) | 2454 | WP_003438437.1 | hypothetical protein | - |
| E1H35_RS06835 (E1H35_06995) | - | 1464160..1464582 (+) | 423 | WP_003428168.1 | phage baseplate protein | - |
| E1H35_RS06840 (E1H35_07000) | - | 1464864..1466393 (+) | 1530 | WP_003438440.1 | NlpC/P60 family protein | - |
| E1H35_RS06845 (E1H35_07005) | - | 1466409..1466735 (+) | 327 | WP_003438447.1 | DUF2577 domain-containing protein | - |
| E1H35_RS06850 (E1H35_07010) | - | 1466735..1467163 (+) | 429 | WP_003438449.1 | DUF2634 domain-containing protein | - |
| E1H35_RS06855 (E1H35_07015) | - | 1467156..1468208 (+) | 1053 | WP_003438450.1 | baseplate J/gp47 family protein | - |
| E1H35_RS06860 (E1H35_07020) | - | 1468205..1468903 (+) | 699 | WP_003438451.1 | putative phage tail protein | - |
| E1H35_RS06865 (E1H35_07025) | - | 1468904..1469887 (+) | 984 | WP_003438452.1 | phage tail protein | - |
Sequence
Protein
Download Length: 348 a.a. Molecular weight: 37377.68 Da Isoelectric Point: 4.8236
>NTDB_id=350062 E1H35_RS06645 WP_003428218.1 1424019..1425065(+) (recA) [Clostridioides difficile strain Cd12]
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEI
DEKVRAFYNLNEEHEESGTSVSKEIVEE
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEI
DEKVRAFYNLNEEHEESGTSVSKEIVEE
Nucleotide
Download Length: 1047 bp
>NTDB_id=350062 E1H35_RS06645 WP_003428218.1 1424019..1425065(+) (recA) [Clostridioides difficile strain Cd12]
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGACATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAGACTACTGTTGCGCTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATATGCAAAAGC
TTTGGGTGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGATTCTCATGTAGGTTTACAAGCTAGACTTATGTCACAAGCACTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCAGAAACTACTACTGGAGGAC
GTGCACTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGATACAATAAAACAAGGTGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTTGTTAAAAACAAAGTAGCACCACCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGGATTTCAAAAATTGGAGACCTTTTAGATATAGCTGCTGATGTAGATATAGTTAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAAGATAATTTAGATTTAACTACTGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAATCAGGTACTTCAGTATCAAAAGAAATTGTAGA
AGAATAA
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGACATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAGACTACTGTTGCGCTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATATGCAAAAGC
TTTGGGTGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGATTCTCATGTAGGTTTACAAGCTAGACTTATGTCACAAGCACTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCAGAAACTACTACTGGAGGAC
GTGCACTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGATACAATAAAACAAGGTGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTTGTTAAAAACAAAGTAGCACCACCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGGATTTCAAAAATTGGAGACCTTTTAGATATAGCTGCTGATGTAGATATAGTTAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAAGATAATTTAGATTTAACTACTGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAATCAGGTACTTCAGTATCAAAAGAAATTGTAGA
AGAATAA
Similar proteins
Only experimentally validated proteins are listed.