Detailed information
Bioinformatically predicted
Overview
| Name | recA | Type | Machinery gene |
| Locus tag | E1H46_RS06625 | Genome accession | NZ_CP037802 |
| Coordinates | 1415073..1416119 (+) | Length | 348 a.a. |
| NCBI ID | WP_003428218.1 | Uniprot ID | A0A031WFI0 |
| Organism | Clostridioides difficile strain Cd23 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1387133..1449705 | 1415073..1416119 | within | 0 |
Gene organization within MGE regions
Location: 1387133..1449705
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E1H46_RS06505 (E1H46_06660) | rimP | 1389549..1390010 (+) | 462 | WP_003438303.1 | ribosome maturation factor RimP | - |
| E1H46_RS06510 (E1H46_06665) | nusA | 1390040..1391194 (+) | 1155 | WP_003428238.1 | transcription termination factor NusA | - |
| E1H46_RS06515 (E1H46_06670) | rnpM | 1391201..1391482 (+) | 282 | WP_003419469.1 | RNase P modulator RnpM | - |
| E1H46_RS06520 (E1H46_06675) | - | 1391472..1391783 (+) | 312 | WP_003419470.1 | L7Ae/L30e/S12e/Gadd45 family ribosomal protein | - |
| E1H46_RS06525 (E1H46_06680) | infB | 1391805..1393745 (+) | 1941 | WP_021363434.1 | translation initiation factor IF-2 | - |
| E1H46_RS06530 (E1H46_06685) | rbfA | 1393788..1394168 (+) | 381 | WP_003428234.1 | 30S ribosome-binding factor RbfA | - |
| E1H46_RS06535 (E1H46_06690) | - | 1394149..1394826 (+) | 678 | Protein_1203 | DHH family phosphoesterase | - |
| E1H46_RS06540 (E1H46_06700) | tnpB | 1395475..1396593 (+) | 1119 | WP_032548186.1 | IS200/IS605 family element RNA-guided endonuclease TnpB | - |
| E1H46_RS06545 (E1H46_06705) | - | 1396711..1397016 (+) | 306 | Protein_1205 | DHH family phosphoesterase | - |
| E1H46_RS06550 (E1H46_06710) | truB | 1397029..1397934 (+) | 906 | WP_003428232.1 | tRNA pseudouridine(55) synthase TruB | - |
| E1H46_RS06555 (E1H46_06715) | - | 1398065..1398994 (+) | 930 | WP_003438310.1 | bifunctional riboflavin kinase/FAD synthetase | - |
| E1H46_RS06560 (E1H46_06725) | rpsO | 1399098..1399355 (+) | 258 | WP_003419491.1 | 30S ribosomal protein S15 | - |
| E1H46_RS06565 (E1H46_06730) | - | 1399595..1400440 (+) | 846 | WP_009889099.1 | DegV family protein | - |
| E1H46_RS06570 (E1H46_06735) | pnp | 1400565..1402676 (+) | 2112 | WP_003438316.1 | polyribonucleotide nucleotidyltransferase | - |
| E1H46_RS06575 (E1H46_06740) | - | 1402941..1403684 (+) | 744 | WP_003438319.1 | polysaccharide deacetylase family protein | - |
| E1H46_RS06580 (E1H46_06745) | - | 1403842..1405089 (+) | 1248 | WP_003438321.1 | M16 family metallopeptidase | - |
| E1H46_RS06585 (E1H46_06750) | - | 1405124..1405369 (+) | 246 | WP_003419503.1 | YlmC/YmxH family sporulation protein | - |
| E1H46_RS06590 (E1H46_06755) | dapG | 1405379..1406602 (+) | 1224 | WP_003438324.1 | aspartate kinase | - |
| E1H46_RS06595 (E1H46_06765) | tnpB | 1407408..1408517 (+) | 1110 | WP_076637467.1 | IS200/IS605 family element RNA-guided endonuclease TnpB | - |
| E1H46_RS06600 (E1H46_06770) | - | 1408704..1409333 (+) | 630 | WP_021363436.1 | ClpP family protease | - |
| E1H46_RS06605 (E1H46_06775) | - | 1409456..1411867 (+) | 2412 | WP_003438328.1 | FtsK/SpoIIIE family DNA translocase | - |
| E1H46_RS06610 (E1H46_06780) | mnmH | 1411870..1412928 (+) | 1059 | WP_003433322.1 | tRNA 2-selenouridine(34) synthase MnmH | - |
| E1H46_RS06615 (E1H46_06785) | rimO | 1412922..1414256 (+) | 1335 | WP_003433320.1 | 30S ribosomal protein S12 methylthiotransferase RimO | - |
| E1H46_RS06620 (E1H46_06790) | pgsA | 1414243..1414785 (+) | 543 | WP_021370268.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase | - |
| E1H46_RS06625 (E1H46_06795) | recA | 1415073..1416119 (+) | 1047 | WP_003428218.1 | recombinase RecA | Machinery gene |
| E1H46_RS06630 (E1H46_06800) | rny | 1416295..1417829 (+) | 1535 | Protein_1222 | ribonuclease Y | - |
| E1H46_RS06635 (E1H46_06805) | - | 1418462..1420243 (+) | 1782 | WP_003438344.1 | UvrD-helicase domain-containing protein | - |
| E1H46_RS06640 (E1H46_06810) | lepB | 1420325..1420855 (-) | 531 | WP_009902411.1 | signal peptidase I | - |
| E1H46_RS06645 (E1H46_06815) | - | 1420895..1421719 (-) | 825 | WP_009905410.1 | undecaprenyl-diphosphate phosphatase | - |
| E1H46_RS06650 (E1H46_06820) | - | 1421976..1422884 (+) | 909 | WP_021363438.1 | tyrosine-type recombinase/integrase | - |
| E1H46_RS06655 (E1H46_06825) | purB | 1423028..1424473 (+) | 1446 | WP_021363439.1 | adenylosuccinate lyase | - |
| E1H46_RS06660 (E1H46_06830) | - | 1424784..1425236 (+) | 453 | WP_003419561.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
| E1H46_RS06665 (E1H46_06835) | - | 1425561..1426757 (-) | 1197 | WP_003438357.1 | pyridoxal phosphate-dependent aminotransferase | - |
| E1H46_RS06670 (E1H46_06840) | galT | 1427142..1428092 (+) | 951 | WP_003438360.1 | galactose-1-phosphate uridylyltransferase | - |
| E1H46_RS06675 (E1H46_06845) | - | 1428253..1429005 (+) | 753 | WP_003438367.1 | exodeoxyribonuclease III | - |
| E1H46_RS06680 (E1H46_06850) | - | 1429097..1429873 (-) | 777 | WP_009896237.1 | 3'-5' exonuclease | - |
| E1H46_RS06685 (E1H46_06855) | - | 1430188..1432086 (+) | 1899 | WP_003428202.1 | glutamine synthetase | - |
| E1H46_RS06690 (E1H46_06860) | - | 1432214..1433335 (-) | 1122 | WP_003428201.1 | MGDG synthase family glycosyltransferase | - |
| E1H46_RS06695 (E1H46_06865) | - | 1433534..1433866 (+) | 333 | WP_009889116.1 | PadR family transcriptional regulator | - |
| E1H46_RS06700 (E1H46_06870) | - | 1433853..1434911 (+) | 1059 | WP_216201223.1 | DUF1700 domain-containing protein | - |
| E1H46_RS06705 (E1H46_06875) | - | 1434904..1435974 (+) | 1071 | WP_011861183.1 | DUF4097 family beta strand repeat-containing protein | - |
| E1H46_RS06710 (E1H46_06880) | - | 1436076..1436612 (+) | 537 | WP_003428196.1 | lipoprotein | - |
| E1H46_RS06715 (E1H46_06885) | - | 1436728..1437435 (+) | 708 | WP_021363440.1 | lantibiotic protection ABC transporter ATP-binding protein | - |
| E1H46_RS06720 (E1H46_06890) | - | 1437437..1438153 (+) | 717 | WP_016729591.1 | lantibiotic immunity ABC transporter MutE/EpiE family permease subunit | - |
| E1H46_RS06725 (E1H46_06895) | - | 1438155..1438913 (+) | 759 | WP_021363441.1 | lantibiotic immunity ABC transporter MutG family permease subunit | - |
| E1H46_RS06730 (E1H46_06900) | - | 1439048..1440436 (+) | 1389 | WP_021363442.1 | two-component system sensor histidine kinase | - |
| E1H46_RS06735 (E1H46_06905) | - | 1440512..1441333 (-) | 822 | WP_009896253.1 | pyridoxamine kinase | - |
| E1H46_RS06740 (E1H46_06910) | - | 1441584..1442738 (+) | 1155 | WP_009892989.1 | amidase domain-containing protein | - |
| E1H46_RS06745 (E1H46_06915) | - | 1442921..1443121 (+) | 201 | WP_003419624.1 | cold-shock protein | - |
| E1H46_RS06750 (E1H46_06920) | - | 1443542..1443970 (+) | 429 | WP_009889129.1 | CBS domain-containing protein | - |
| E1H46_RS06755 (E1H46_06925) | - | 1444113..1444868 (-) | 756 | WP_009889131.1 | peptidylprolyl isomerase | - |
| E1H46_RS06760 (E1H46_06935) | - | 1445569..1446075 (-) | 507 | WP_011861186.1 | ImmA/IrrE family metallo-endopeptidase | - |
| E1H46_RS06765 (E1H46_06940) | - | 1446157..1446477 (-) | 321 | WP_003428185.1 | XRE family transcriptional regulator | - |
| E1H46_RS06770 (E1H46_06945) | - | 1446645..1446842 (+) | 198 | WP_003419641.1 | helix-turn-helix transcriptional regulator | - |
| E1H46_RS06775 (E1H46_06950) | - | 1446946..1447386 (+) | 441 | WP_003428183.1 | hypothetical protein | - |
| E1H46_RS06780 (E1H46_06955) | - | 1447635..1448078 (+) | 444 | WP_009896258.1 | phage tail terminator family protein | - |
| E1H46_RS06785 (E1H46_06960) | - | 1448083..1449147 (+) | 1065 | WP_021363443.1 | phage tail sheath subtilisin-like domain-containing protein | - |
| E1H46_RS06790 (E1H46_06965) | - | 1449161..1449589 (+) | 429 | WP_003419646.1 | phage tail tube protein | - |
Sequence
Protein
Download Length: 348 a.a. Molecular weight: 37377.68 Da Isoelectric Point: 4.8236
>NTDB_id=349977 E1H46_RS06625 WP_003428218.1 1415073..1416119(+) (recA) [Clostridioides difficile strain Cd23]
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEI
DEKVRAFYNLNEEHEESGTSVSKEIVEE
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEI
DEKVRAFYNLNEEHEESGTSVSKEIVEE
Nucleotide
Download Length: 1047 bp
>NTDB_id=349977 E1H46_RS06625 WP_003428218.1 1415073..1416119(+) (recA) [Clostridioides difficile strain Cd23]
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGACATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAGACTACTGTTGCGCTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATATGCAAAAGC
TTTGGGTGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGATTCTCATGTAGGTTTACAAGCTAGACTTATGTCACAAGCACTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCAGAAACTACTACTGGAGGAC
GTGCACTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGATACAATAAAACAAGGTGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTTGTTAAAAACAAAGTAGCACCACCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGGATTTCAAAAATTGGAGACCTTTTAGATATAGCTGCTGATGTAGATATAGTTAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAAGATAATTTAGATTTAACTACTGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAATCAGGTACTTCAGTATCAAAAGAAATTGTAGA
AGAATAA
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGACATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAGACTACTGTTGCGCTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATATGCAAAAGC
TTTGGGTGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGATTCTCATGTAGGTTTACAAGCTAGACTTATGTCACAAGCACTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCAGAAACTACTACTGGAGGAC
GTGCACTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGATACAATAAAACAAGGTGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTTGTTAAAAACAAAGTAGCACCACCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGGATTTCAAAAATTGGAGACCTTTTAGATATAGCTGCTGATGTAGATATAGTTAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAAGATAATTTAGATTTAACTACTGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAATCAGGTACTTCAGTATCAAAAGAAATTGTAGA
AGAATAA
Similar proteins
Only experimentally validated proteins are listed.