Detailed information NTG0341345

Bioinformatically predicted

Overview

• Name: recA
• Type: Machinery gene
• Locus tag: ETT66_RS08650
• Genome accession: NZ_CP035433
• Coordinates: 1721706..1722842 (-)
• Length: 378 a.a.
• NCBI ID: WP_002992179.1
• Uniprot ID: A0A4Q1QZP2
• Organism: Streptococcus pyogenes strain emm65
• Function: homologous recombination (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1719815..1720883	1721706..1722842	flank	823

Gene organization within MGE regions

Location: 1719815..1722842

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT66_RS08640 (ETT66_08635)	-	1719815..1720883 (-)	1069	Protein_1601	ISAs1 family transposase	-
ETT66_RS08645 (ETT66_08640)	spx	1721017..1721415 (-)	399	WP_002982188.1	transcriptional regulator Spx	-
ETT66_RS08650 (ETT66_08645)	recA	1721706..1722842 (-)	1137	WP_002992179.1	recombinase RecA	Machinery gene

Sequence

Protein

• Length: 378 a.a.
• Molecular weight: 40631.23 Da
• Isoelectric Point: 4.9004

>NTDB_id=341345 ETT66_RS08650 WP_002992179.1 1721706..1722842(-) (recA) [Streptococcus pyogenes strain emm65]
MAKKLKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGERAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGP
ESSGKTTVALHAVAQAQKEGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGNPETTPGGRALKFYASVRLDVRG
TTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAEVEIMYGEGISRTGELVKIASDLDIIQKAGAWFSYNGEKIGQGSE
NAKRYLADHPQLFDEIDRKVRVKFGLLEESEEESAMAVASEETDDLALDLDNGIEIED

Nucleotide

• Length: 1137 bp

>NTDB_id=341345 ETT66_RS08650 WP_002992179.1 1721706..1722842(-) (recA) [Streptococcus pyogenes strain emm65]
TTGGCAAAAAAATTAAAAAAGAATGAAGAAATCACTAAGAAGTTTGGTGACGAACGTCGCAAAGCCCTTGATGATGCTTT
GAAAAATATTGAAAAAGATTTTGGTAAGGGCGCAGTGATGCGATTAGGAGAACGTGCAGAGCAAAAAGTTCAGGTTATGA
GTTCAGGAAGTCTAGCTCTTGATATTGCGCTTGGAGCTGGTGGTTATCCTAAAGGACGTATCATCGAAATCTATGGTCCA
GAGTCTTCCGGTAAAACGACTGTGGCTTTACATGCTGTAGCACAAGCTCAAAAAGAAGGTGGAATCGCAGCCTTTATCGA
TGCCGAGCATGCGCTTGATCCAGCTTATGCTGCTGCGCTTGGGGTTAATATTGATGAACTCCTCTTGTCTCAACCAGATT
CTGGAGAACAAGGACTTGAAATTGCAGGTAAATTGATTGATTCTGGTGCGGTTGATCTGGTTGTTGTCGATTCAGTAGCA
GCTTTAGTGCCACGTGCTGAAATTGATGGTGATATTGGCGATAGCCATGTCGGATTGCAAGCACGTATGATGAGTCAGGC
CATGCGTAAATTATCAGCTTCTATTAATAAAACAAAAACTATCGCTATCTTTATTAACCAATTGCGTGAAAAAGTTGGTG
TGATGTTTGGAAATCCTGAAACAACACCAGGTGGTCGAGCTTTGAAATTCTATGCTTCTGTTCGGCTGGATGTGCGTGGA
ACAACTCAAATTAAAGGAACTGGTGACCAAAAAGATAGCAGCATTGGTAAGGAGACCAAAATCAAGGTTGTTAAAAACAA
GGTCGCTCCGCCATTTAAGGTAGCAGAAGTTGAAATCATGTATGGGGAAGGTATTTCTCGTACAGGGGAGCTTGTGAAAA
TTGCTTCTGATTTGGACATTATCCAAAAAGCAGGTGCTTGGTTCTCTTATAATGGTGAGAAGATTGGCCAAGGTTCTGAA
AATGCTAAGCGTTATTTGGCCGATCATCCACAATTGTTTGATGAAATCGACCGTAAAGTACGTGTTAAATTTGGTTTGCT
TGAAGAAAGCGAAGAAGAATCTGCTATGGCAGTAGCATCAGAAGAAACCGATGATCTTGCTTTAGATTTAGATAATGGTA
TTGAAATTGAAGATTAA

Domains

Predicted by InterproScan.

• recA bacterial DNA recombination protein (RecA) (21-286)

3D structure

• AlphaFold DB: A0A4Q1QZP2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
recA	Streptococcus pyogenes NZ131	99.735	100	0.997
recA	Streptococcus mutans UA159	87.467	100	0.886
recA	Streptococcus mitis NCTC 12261	85.34	100	0.862
recA	Streptococcus pneumoniae Rx1	84.416	100	0.86
recA	Streptococcus pneumoniae D39	84.416	100	0.86
recA	Streptococcus pneumoniae R6	84.416	100	0.86
recA	Streptococcus pneumoniae TIGR4	84.416	100	0.86
recA	Streptococcus mitis SK321	85.302	100	0.86
recA	Lactococcus lactis subsp. cremoris KW2	78.754	93.386	0.735
recA	Latilactobacillus sakei subsp. sakei 23K	70.623	89.153	0.63
recA	Bacillus subtilis subsp. subtilis str. 168	68.085	87.037	0.593
recA	Acinetobacter baylyi ADP1	60	92.593	0.556
recA	Acinetobacter baumannii D1279779	59.49	93.386	0.556
recA	Riemerella anatipestifer ATCC 11845 = DSM 15868	62.018	89.153	0.553
recA	Neisseria gonorrhoeae MS11	60.058	90.741	0.545
recA	Neisseria gonorrhoeae MS11	60.058	90.741	0.545
recA	Neisseria gonorrhoeae strain FA1090	60.058	90.741	0.545
recA	Vibrio cholerae strain A1552	58.286	92.593	0.54
recA	Vibrio cholerae O1 biovar El Tor strain E7946	58.286	92.593	0.54
recA	Glaesserella parasuis strain SC1401	59.706	89.947	0.537
recA	Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539	62.539	85.45	0.534
recA	Pseudomonas stutzeri DSM 10701	56.897	92.063	0.524
recA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.912	87.566	0.516
recA	Helicobacter pylori 26695	58.084	88.36	0.513
recA	Helicobacter pylori strain NCTC11637	58.084	88.36	0.513
recA	Ralstonia pseudosolanacearum GMI1000	57.831	87.831	0.508