Detailed information NTG0325864

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: FNL90_RS03240
• Genome accession: NZ_CP041408
• Coordinates: 608106..610349 (+)
• Length: 747 a.a.
• NCBI ID: WP_047235228.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 37-97S
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 603106..615349

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FNL90_RS03215 (FNL90_03325)	-	603337..605337 (+)	2001	WP_030126409.1	potassium transporter Kup	-
FNL90_RS03220 (FNL90_03330)	-	605361..605639 (-)	279	WP_002989164.1	GIY-YIG nuclease family protein	-
FNL90_RS03225 (FNL90_03335)	-	605629..606405 (-)	777	WP_080342690.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
FNL90_RS03230 (FNL90_03340)	-	606523..607263 (+)	741	WP_002989170.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
FNL90_RS03235 (FNL90_03345)	-	607463..608125 (+)	663	WP_002983967.1	ComEA family DNA-binding protein	-
FNL90_RS03240 (FNL90_03350)	comEC/celB	608106..610349 (+)	2244	WP_047235228.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
FNL90_RS03245 (FNL90_03355)	holA	610420..611460 (+)	1041	WP_047235229.1	DNA polymerase III subunit delta	-
FNL90_RS03250 (FNL90_03360)	sodA	611557..612162 (+)	606	WP_023612500.1	superoxide dismutase SodA	-
FNL90_RS03255 (FNL90_03365)	-	612324..612551 (+)	228	WP_011054657.1	hypothetical protein	-
FNL90_RS03260 (FNL90_03370)	-	612536..612784 (+)	249	WP_047235230.1	hypothetical protein	-
FNL90_RS03265 (FNL90_03375)	-	612781..613371 (+)	591	WP_002983984.1	serine hydrolase	-
FNL90_RS03270 (FNL90_03380)	-	613485..614705 (-)	1221	WP_047235231.1	DUF3114 domain-containing protein	-

Sequence

Protein

• Length: 747 a.a.
• Molecular weight: 85517.34 Da
• Isoelectric Point: 9.6063

>NTDB_id=325864 FNL90_RS03240 WP_047235228.1 608106..610349(+) (comEC/celB) [Streptococcus pyogenes strain 37-97S]
MTFSWTKLVPLSKIQFAFLILVLFYQIHSPSWLTFLLSLSLICLLVKRLSKKEFLGVFAILSFCALFLLYQKQQLIQKLE
IQPVQITSVALVPDSIRINGDQLAVLGRHGKHSYQLFYRLKSQAEAQLFKKEHRWLVMHAKVTLEKAEEVRNFKGFNYQT
FLAYQGIYRIGKVEQIEQLEVISPESICDYLSSLRRRAIVHCQQHFPRPMSHYLTGLLFGYLDKSFGEMTDYYSQLGIIH
LFALSGMQVGFFLTCFRRVLLLLAVPLEWIKWIELPFACFYAALTGYSISVIRSLVQSQLRHLGIKGLDNLACTFLLVFL
WDAHFLMTVGGVLTFSYAFLLTVVTVEELSGAKRQLVQDLTISLGILPFLLFYFSSFNPMSMVLTGLLSYLFDLFILPLL
CLVFCLSPLVTVSICNHLFILLEKVIQFLGNTFNSSLVFGSPTSWHLLILVISFAIFYDYRQVRQRVITCGLVIALTLLS
VKYPLTNEVTFIDIGQGDSILVREWTGKNLLIDVGGRPFFSSKEHWRRGHHVANAQKTLIPYLKSRGIHTIDQLLVTHAD
TDHMGDIEVVAKAIRIKEILTSQGSLSHPSFVRRLRRLKCHVRVLAAGDQLPIMGSVLQVLYPWQLGDGKNNDSLVLYGR
LLNRTFLFTGDLEKEGENEIIKRYPQLRVDYLKAGHHGSNTSSSAAFLDHIQPKVAFISAGKNNRYQHPHRETLARLEDR
QITYYRTDTQGAIRLTGWTSWHLETVR

Nucleotide

• Length: 2244 bp

>NTDB_id=325864 FNL90_RS03240 WP_047235228.1 608106..610349(+) (comEC/celB) [Streptococcus pyogenes strain 37-97S]
ATGACATTTTCTTGGACTAAGCTAGTGCCCCTGTCAAAGATTCAATTTGCTTTTTTAATCTTGGTTCTCTTTTATCAAAT
CCATAGCCCTAGCTGGTTAACGTTTCTCCTTAGCCTTAGTTTGATTTGCTTACTTGTCAAGCGTTTGTCTAAAAAAGAAT
TTCTCGGTGTCTTTGCCATCCTTAGTTTCTGTGCTTTGTTTTTGCTGTATCAGAAACAGCAGTTGATTCAAAAACTGGAA
ATTCAGCCAGTACAAATAACCTCTGTAGCATTAGTTCCTGATAGTATTCGGATTAATGGTGATCAATTAGCTGTTCTTGG
ACGTCACGGGAAACATTCTTATCAGTTATTTTACCGTTTGAAAAGCCAAGCAGAAGCCCAATTGTTCAAGAAAGAGCACC
GTTGGTTAGTGATGCACGCAAAAGTGACATTGGAAAAAGCTGAGGAAGTTCGAAATTTTAAAGGCTTTAATTATCAGACT
TTTTTGGCTTATCAAGGAATTTACAGGATAGGGAAGGTAGAGCAAATAGAACAGCTTGAAGTGATTTCACCCGAGTCAAT
ATGTGACTATTTGTCCTCTTTAAGACGACGAGCCATTGTTCATTGCCAGCAGCATTTTCCAAGACCTATGTCACACTACC
TGACGGGCCTCCTTTTTGGTTATTTAGATAAGTCGTTTGGTGAGATGACAGATTATTATAGTCAGTTGGGTATCATTCAT
CTCTTTGCTTTATCAGGGATGCAGGTTGGCTTCTTTCTCACTTGTTTTAGAAGGGTGTTGCTATTACTCGCAGTTCCTTT
GGAATGGATAAAATGGATAGAGCTTCCTTTTGCTTGCTTTTATGCCGCGTTGACAGGTTATAGTATTTCTGTTATTCGAA
GCCTCGTGCAGTCGCAGTTGCGTCATTTAGGAATAAAAGGATTAGACAATCTGGCTTGTACTTTTTTACTTGTCTTTTTA
TGGGATGCTCATTTCTTAATGACTGTTGGTGGCGTATTAACGTTTAGCTATGCTTTTTTGTTAACAGTGGTTACTGTTGA
AGAATTATCAGGAGCTAAAAGACAGTTGGTACAAGACTTGACCATTTCCCTAGGAATATTACCATTTTTGCTCTTTTATT
TTTCCAGTTTTAACCCCATGTCAATGGTCTTAACAGGGCTCTTGTCTTATCTCTTTGACCTTTTTATTTTGCCCCTTCTT
TGTCTGGTTTTTTGTCTATCCCCTTTGGTGACTGTCTCAATATGTAACCATCTTTTTATTTTATTAGAAAAAGTCATTCA
ATTTCTCGGAAATACTTTCAATAGTTCCCTTGTTTTTGGAAGCCCGACCAGTTGGCACTTGCTTATCTTGGTGATTAGCT
TCGCTATTTTTTATGATTATCGGCAGGTGCGACAACGAGTTATCACTTGCGGTTTGGTTATAGCGTTGACGCTTTTGTCT
GTCAAATATCCTTTGACCAATGAAGTGACCTTTATCGACATTGGCCAGGGAGATAGTATTTTGGTGAGGGAGTGGACAGG
GAAAAATCTCTTAATAGATGTAGGTGGGCGCCCTTTCTTTTCTTCAAAAGAGCACTGGCGACGAGGACATCACGTAGCTA
ATGCTCAGAAAACCTTAATTCCTTACTTAAAAAGTAGAGGTATTCACACAATTGACCAACTATTAGTAACTCACGCAGAT
ACTGATCATATGGGGGATATCGAAGTGGTTGCCAAAGCTATTCGGATAAAGGAGATTTTGACTAGCCAAGGCAGTTTAAG
CCATCCAAGCTTTGTTAGGCGGCTAAGGCGTTTAAAATGTCACGTTAGGGTTTTAGCAGCTGGAGACCAGTTGCCTATTA
TGGGAAGTGTCTTACAGGTGCTCTACCCTTGGCAGTTAGGGGACGGGAAAAATAACGATTCTTTGGTACTTTATGGCAGG
CTCTTAAATCGAACTTTTCTTTTCACAGGTGACTTGGAAAAAGAGGGGGAAAACGAGATCATAAAACGTTATCCTCAACT
AAGAGTAGATTATTTAAAAGCAGGTCACCATGGATCAAATACCTCTTCTAGTGCAGCTTTTTTAGACCATATTCAGCCTA
AAGTGGCCTTTATTTCTGCTGGAAAAAATAACCGTTATCAGCATCCTCACAGAGAAACCTTAGCCCGTTTGGAAGACAGA
CAAATTACTTATTACCGAACGGATACGCAAGGAGCTATTCGTTTGACTGGTTGGACAAGCTGGCATCTTGAAACGGTCCG
TTAG

Domains

Predicted by InterProScan.

• Competence protein (Competence) (217-462)

• Metallo-beta-lactamase superfamily (Lactamase_B) (495-701)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	46.319	100	0.463
comEC/celB	Streptococcus mitis NCTC 12261	46.113	99.866	0.461
comEC/celB	Streptococcus pneumoniae TIGR4	45.114	100	0.451
comEC/celB	Streptococcus pneumoniae Rx1	44.92	100	0.45
comEC/celB	Streptococcus pneumoniae D39	44.92	100	0.45
comEC/celB	Streptococcus pneumoniae R6	44.92	100	0.45
comEC	Lactococcus lactis subsp. cremoris KW2	40.671	99.732	0.406