Detailed information NTG0302864

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: ETT51_RS01980
• Genome accession: NZ_CP035448
• Coordinates: 357543..358133 (+)
• Length: 196 a.a.
• NCBI ID: WP_002985850.1
• Uniprot ID: A0A9X9QW05
• Organism: Streptococcus pyogenes strain emm70
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 352543..363133

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT51_RS01960 (ETT51_01970)	-	353355..354800 (-)	1446	WP_002985858.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
ETT51_RS01965 (ETT51_01975)	-	354888..356522 (+)	1635	WP_063632594.1	polysaccharide biosynthesis protein	-
ETT51_RS01970 (ETT51_01980)	upp	356690..357319 (+)	630	WP_002985854.1	uracil phosphoribosyltransferase	-
ETT51_RS01980 (ETT51_01990)	clpP	357543..358133 (+)	591	WP_002985850.1	ATP-dependent Clp protease proteolytic subunit	Regulator
ETT51_RS01985 (ETT51_02000)	-	358625..358900 (+)	276	WP_002985847.1	YlbG family protein	-
ETT51_RS01990 (ETT51_02005)	tmk	359149..359784 (+)	636	WP_011184214.1	dTMP kinase	-
ETT51_RS01995 (ETT51_02010)	-	359802..360677 (+)	876	WP_038432816.1	DNA polymerase III subunit delta'	-
ETT51_RS02000 (ETT51_02015)	-	360696..360935 (+)	240	WP_030126140.1	PSP1 C-terminal domain-containing protein	-
ETT51_RS02005 (ETT51_02020)	yabA	361340..361663 (+)	324	WP_002985838.1	DNA replication initiation control protein YabA	-
ETT51_RS02010 (ETT51_02025)	rsmI	361668..362531 (+)	864	WP_010921933.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
ETT51_RS02015 (ETT51_02030)	-	362558..362950 (+)	393	WP_002985833.1	DUF5684 domain-containing protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21648.88 Da
• Isoelectric Point: 5.2834

>NTDB_id=302864 ETT51_RS01980 WP_002985850.1 357543..358133(+) (clpP) [Streptococcus pyogenes strain emm70]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK

Nucleotide

• Length: 591 bp

>NTDB_id=302864 ETT51_RS01980 WP_002985850.1 357543..358133(+) (clpP) [Streptococcus pyogenes strain emm70]
ATGATTCCTGTTGTTATTGAACAAACTAGCCGTGGAGAACGTTCTTATGACATTTATTCACGTTTATTAAAAGACCGTAT
TATCATGTTAACAGGGCCTGTCGAAGACAACATGGCCAACTCTGTCATAGCGCAGCTCTTATTCCTTGACGCGCAAGACA
ACACGAAAGATATCTACCTATATGTCAACACACCAGGTGGCTCTGTCTCAGCAGGCTTGGCTATTGTCGATACCATGAAC
TTTATCAAGGCCGATGTGCAAACTATTGTCATGGGTATGGCAGCTTCTATGGGGACAGTCATTGCTTCATCAGGAACAAA
AGGCAAACGCTTTATGTTACCAAATGCAGAGTATATGATCCACCAGCCAATGGGTGGCACAGGCGGTGGCACGCAACAAA
CGGATATGGCTATCGCAGCAGAACATCTCTTAAAAACACGTCACCGTTTAGAAAAAATCTTAGCGCAAAATGCTGGAAAA
ACGATTAAACAAATTCATAAAGATGCTGAGCGTGATTATTGGATGAGTGCTGAAGAAACCTTGGCTTACGGTTTCATTGA
TGAAATCATGGAAAACAACGAACTAAAATAA

Domains

Predicted by InterProScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A9X9QW05

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pyogenes MGAS315	100	100	1
clpP	Streptococcus pyogenes JRS4	100	100	1
clpP	Streptococcus mutans UA159	90.816	100	0.908
clpP	Streptococcus pneumoniae Rx1	90.769	99.49	0.903
clpP	Streptococcus pneumoniae D39	90.769	99.49	0.903
clpP	Streptococcus pneumoniae R6	90.769	99.49	0.903
clpP	Streptococcus pneumoniae TIGR4	90.769	99.49	0.903
clpP	Streptococcus thermophilus LMG 18311	89.796	100	0.898
clpP	Streptococcus thermophilus LMD-9	89.796	100	0.898
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	86.224	100	0.862
clpP	Lactococcus lactis subsp. cremoris KW2	85.714	100	0.857
clpP	Bacillus subtilis subsp. subtilis str. 168	57.143	100	0.571
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.995	98.469	0.561