Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   DLJ52_RS10085 Genome accession   NZ_CP029559
Coordinates   2075351..2077297 (-) Length   648 a.a.
NCBI ID   WP_109982790.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain NIDR 6715-15     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2070351..2082297
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DLJ52_RS10060 (DLJ52_10060) - 2071109..2073022 (+) 1914 WP_019775059.1 ABC transporter ATP-binding protein/permease -
  DLJ52_RS10065 (DLJ52_10065) - 2073061..2073324 (+) 264 WP_109982789.1 hypothetical protein -
  DLJ52_RS10070 (DLJ52_10070) - 2073374..2073775 (+) 402 WP_019777428.1 helix-turn-helix transcriptional regulator -
  DLJ52_RS10075 (DLJ52_10075) - 2073809..2074360 (-) 552 WP_002960562.1 DNA-3-methyladenine glycosylase I -
  DLJ52_RS10080 (DLJ52_10080) ruvA 2074529..2075119 (-) 591 WP_019769153.1 Holliday junction branch migration protein RuvA Machinery gene
  DLJ52_RS10085 (DLJ52_10085) hexB 2075351..2077297 (-) 1947 WP_109982790.1 DNA mismatch repair endonuclease MutL Machinery gene
  DLJ52_RS10090 (DLJ52_10090) hexA 2077538..2080099 (-) 2562 WP_109982791.1 DNA mismatch repair protein MutS Machinery gene
  DLJ52_RS10095 (DLJ52_10095) - 2080086..2080439 (-) 354 WP_019787291.1 YlbF family regulator -
  DLJ52_RS10100 (DLJ52_10100) argR 2080432..2080866 (-) 435 WP_019775054.1 arginine repressor -

Sequence

Protein


Download         Length: 648 a.a.        Molecular weight: 73102.32 Da        Isoelectric Point: 5.5931

>NTDB_id=254147 DLJ52_RS10085 WP_109982790.1 2075351..2077297(-) (hexB) [Streptococcus sobrinus strain NIDR 6715-15]
MSKIIELPEVLANQIAAGEVVERPSSVVKELVENAIDAGSTQITVEIEESGLKKIQVTDNGQGIENDDVALSLRRHATSK
IKNQADLFRIRTLGFRGEALPSIASISDLTIKTAVKGADHGTLLVAKGGEILSQEPISTPVGTKITVEDLFFNTPARLKY
MKSLQAELGHIVDVINRQSLGHPEIAFTLINDGRELTKTTGTGDLRQAIAGIYGLNTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPLAVIDIQIDPYLADVNVHPTKQEVRISKEKELMQLIRK
AIAESLREQDLIPDALENLAKSSVRKADKPVQTSLPLKQTNLYYDQARQDFFLKSDNQVAENQSNQPSRPVNQVDKAVKP
TDSVRQAQRPEPDVQDQEHPDIDFSKKTQTHKLMVRLDQEASSSFPELDYFGQMQGTYLFAQGQGGLYIIDQHAAQERVK
YEYYREKIGEVDSSLQQLLVPYLFEFRAEDFINLQEKMTLLNQVGIYLEPYGNNTFILREHPIWMKEEEIESGVYEMCDM
LLLTDEVSIKVYRAELAIMMSCKRSIKANHALDDYSASNLLVQLSQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHT
SLRELGKY

Nucleotide


Download         Length: 1947 bp        

>NTDB_id=254147 DLJ52_RS10085 WP_109982790.1 2075351..2077297(-) (hexB) [Streptococcus sobrinus strain NIDR 6715-15]
ATGTCAAAAATTATTGAATTGCCAGAGGTTCTGGCCAATCAGATTGCTGCCGGTGAGGTTGTTGAGCGGCCCAGCAGCGT
TGTTAAAGAATTAGTCGAGAATGCTATCGATGCCGGTAGCACACAAATTACAGTTGAAATCGAAGAATCCGGTCTCAAGA
AAATTCAGGTGACCGACAACGGCCAAGGCATTGAAAATGACGATGTGGCCCTCAGTCTGCGTCGTCACGCCACCAGTAAA
ATCAAAAATCAGGCGGATCTCTTTCGGATTCGGACCTTGGGATTTCGGGGTGAGGCCCTGCCGTCAATTGCCTCAATTAG
CGATTTGACGATTAAGACAGCGGTCAAGGGTGCAGACCACGGGACCCTGCTGGTCGCTAAAGGCGGAGAAATCCTCTCCC
AAGAGCCTATCAGTACCCCTGTCGGCACTAAGATTACGGTTGAGGATCTCTTCTTTAATACTCCAGCCCGCCTCAAGTAC
ATGAAGTCCCTCCAGGCAGAGTTGGGGCACATTGTTGATGTCATCAATCGTCAAAGCCTGGGGCACCCCGAGATTGCCTT
TACCCTGATTAATGATGGGCGTGAGTTGACCAAGACCACCGGCACTGGTGACCTGCGTCAGGCCATTGCTGGTATCTATG
GTCTCAATACAGCTAAGAAGATGGTCGAAATTTCCAATAGTGACTTGGATTTCGAGGTATCAGGCTATGTCAGTCTGCCT
GAATTGACTAGAGCCAATCGCAACTACATCACCATCCTCATCAACGGTCGCTACATCAAGAATTTCCTTCTCAATCGGGC
CATTTTAGATGGCTATGGCTCCAAGCTCATGGTCGGTCGCTTTCCCCTAGCTGTGATTGACATCCAGATTGACCCCTATT
TGGCCGATGTCAATGTCCATCCAACCAAGCAGGAAGTCCGGATTTCTAAGGAAAAAGAGCTCATGCAGCTGATTCGCAAG
GCAATTGCTGAGAGCTTGCGAGAGCAGGATTTGATTCCAGATGCCTTGGAAAATCTGGCCAAATCTAGTGTTCGCAAGGC
TGACAAACCTGTTCAGACCAGCCTGCCGCTCAAGCAGACCAATCTCTATTACGACCAGGCCCGTCAGGATTTCTTCCTTA
AATCGGACAATCAAGTGGCAGAAAACCAGTCAAACCAGCCTTCTCGACCTGTCAATCAAGTTGACAAGGCTGTCAAGCCG
ACGGATTCTGTCAGACAAGCCCAAAGGCCTGAACCAGATGTCCAGGACCAGGAACATCCTGATATTGACTTTTCCAAGAA
GACTCAGACCCATAAATTGATGGTTCGCCTGGACCAAGAAGCAAGCTCAAGCTTCCCTGAGTTGGATTATTTTGGTCAGA
TGCAGGGCACCTATCTCTTTGCCCAAGGACAAGGTGGCCTTTATATCATTGACCAACACGCTGCTCAGGAGCGGGTCAAA
TACGAATACTACCGAGAAAAAATTGGTGAGGTTGACAGTTCTTTACAGCAGCTCTTGGTTCCCTATCTCTTTGAATTTCG
GGCGGAAGACTTCATTAACCTTCAAGAAAAAATGACTCTCCTCAACCAAGTGGGTATCTATCTAGAACCCTATGGTAACA
ATACCTTTATCCTGCGGGAGCACCCCATCTGGATGAAGGAGGAAGAGATTGAATCGGGTGTTTACGAGATGTGCGACATG
CTCCTTTTGACGGATGAGGTTTCTATCAAGGTCTATCGGGCTGAGCTAGCTATCATGATGAGCTGTAAACGCTCCATCAA
GGCCAACCATGCCCTAGATGACTATTCGGCCAGCAATCTTCTAGTCCAACTATCCCAATGTAAAAATCCCTATAATTGTC
CCCATGGCCGGCCGGTCCTGGTTAATTTCACCAAGTCTGATATGGAAAAAATGTTCCGTCGGATTCAAGAGAACCATACC
AGCCTAAGGGAACTGGGGAAATATTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(450-592)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

71.516

100

0.721

Multiple sequence alignment