Detailed information NTG0247945

Bioinformatically predicted

Overview

• Name: comR/comR2
• Type: Regulator
• Locus tag: CO687_RS03155
• Genome accession: NZ_CP023511
• Coordinates: 655778..656260 (+)
• Length: 160 a.a.
• NCBI ID: WP_048778891.1
• Uniprot ID: A0AB35FPE6
• Organism: Streptococcus gordonii strain FDAARGOS_371
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	641454..664393	655778..656260	within	0

Gene organization within MGE regions

Location: 641454..664393

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CO687_RS03070 (CO687_03070)	comC/comC1	641454..641618 (+)	165	WP_080998577.1	bacteriocin	Regulator
CO687_RS03075 (CO687_03075)	comD/comD2	641631..642992 (+)	1362	WP_301335837.1	competence system sensor histidine kinase ComD	Regulator
CO687_RS03080 (CO687_03080)	comE/comE2	642989..643756 (+)	768	WP_008808031.1	competence system response regulator transcription factor ComE	Regulator
CO687_RS03095 (CO687_03095)	ychF	644078..645193 (+)	1116	WP_008808030.1	redox-regulated ATPase YchF	-
CO687_RS03100 (CO687_03100)	pth	645267..645836 (+)	570	WP_096754921.1	aminoacyl-tRNA hydrolase	-
CO687_RS03105 (CO687_03105)	mfd	645829..649332 (+)	3504	WP_096754922.1	transcription-repair coupling factor	-
CO687_RS03110 (CO687_03110)	-	649398..649664 (+)	267	WP_012131074.1	RNA-binding S4 domain-containing protein	-
CO687_RS03115 (CO687_03115)	-	649657..650025 (+)	369	WP_060970645.1	septum formation initiator family protein	-
CO687_RS03120 (CO687_03120)	-	650028..650147 (+)	120	WP_037622626.1	SP_0009 family protein	-
CO687_RS03125 (CO687_03125)	-	650147..651427 (+)	1281	WP_045772579.1	serine hydrolase	-
CO687_RS03130 (CO687_03130)	tilS	651424..652701 (+)	1278	WP_008808024.1	tRNA lysidine(34) synthetase TilS	-
CO687_RS03135 (CO687_03135)	hpt	652706..653248 (+)	543	WP_060970644.1	hypoxanthine phosphoribosyltransferase	-
CO687_RS03140 (CO687_03140)	ftsH	653267..655249 (+)	1983	WP_046164766.1	ATP-dependent zinc metalloprotease FtsH	-
CO687_RS03155 (CO687_03155)	comR/comR2	655778..656260 (+)	483	WP_048778891.1	sigma-70 family RNA polymerase sigma factor	Regulator
CO687_RS03265 (CO687_03265)	mreC	663076..663891 (+)	816	WP_061596025.1	rod shape-determining protein MreC	-
CO687_RS03270 (CO687_03270)	mreD	663893..664393 (+)	501	WP_061602340.1	rod shape-determining protein MreD	-

Sequence

Protein

• Length: 160 a.a.
• Molecular weight: 19930.88 Da
• Isoelectric Point: 9.6143

>NTDB_id=247945 CO687_RS03155 WP_048778891.1 655778..656260(+) (comR/comR2) [Streptococcus gordonii strain FDAARGOS_371]
MKFEDVYKQVEGIVKRCYKDYYLHLWEYADWRQEGMLVLYELLKSHPNLLEDHPRLYRYFKTKFRNRIHDLIRRQESQKR
KLDRQPYEEVSEIGHRLRMKELYLDELVAFRSAMAEYRSQLSPEESKQYERLMADERFKGRKAMLKNLSYHLRDFNPRLD

Nucleotide

• Length: 483 bp

>NTDB_id=247945 CO687_RS03155 WP_048778891.1 655778..656260(+) (comR/comR2) [Streptococcus gordonii strain FDAARGOS_371]
ATGAAGTTTGAGGACGTATACAAACAAGTTGAAGGGATAGTCAAGCGCTGTTATAAAGATTATTATCTGCACTTATGGGA
GTATGCAGATTGGAGGCAGGAAGGAATGTTGGTGTTGTACGAATTATTAAAAAGTCATCCCAACCTACTGGAAGATCATC
CACGCCTGTACCGTTACTTCAAGACCAAGTTTCGGAACAGAATTCATGATTTGATTCGTCGCCAAGAGAGTCAAAAGCGG
AAATTGGACAGGCAACCCTATGAAGAGGTCAGCGAGATAGGTCATCGTTTAAGAATGAAAGAGCTGTATCTGGATGAATT
GGTAGCCTTTAGAAGTGCAATGGCAGAGTATAGAAGTCAGCTCAGTCCAGAAGAATCAAAACAATATGAGCGTCTGATGG
CAGATGAAAGGTTCAAAGGACGTAAGGCAATGCTCAAAAATCTATCCTATCACTTAAGGGATTTCAATCCCCGTTTAGAT
TAA

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	96.875	100	0.969
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	96.875	100	0.969
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	49.359	97.5	0.481
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	48.718	97.5	0.475
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	48.718	97.5	0.475
comX/comX1	Streptococcus pneumoniae Rx1	48.077	97.5	0.469
comX/comX2	Streptococcus pneumoniae D39	48.077	97.5	0.469
comX/comX1	Streptococcus pneumoniae D39	48.077	97.5	0.469
comX/comX2	Streptococcus pneumoniae R6	48.077	97.5	0.469
comX/comX1	Streptococcus pneumoniae R6	48.077	97.5	0.469
comX/comX1	Streptococcus pneumoniae TIGR4	48.077	97.5	0.469
comX/comX2	Streptococcus pneumoniae Rx1	48.077	97.5	0.469
comX/comX2	Streptococcus pneumoniae TIGR4	48.077	97.5	0.469
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	47.436	97.5	0.463
comX/sigX	Streptococcus suis P1/7	47.742	96.875	0.463
comX/sigX	Streptococcus suis D9	47.742	96.875	0.463
comX/sigX	Streptococcus suis isolate S10	47.742	96.875	0.463
comX/sigX	Streptococcus mutans UA159	46.795	97.5	0.456
comX	Streptococcus thermophilus LMG 18311	43.871	96.875	0.425
comX	Streptococcus thermophilus LMD-9	43.871	96.875	0.425
comX/sigX	Streptococcus salivarius strain HSISS4	43.226	96.875	0.419
comX	Streptococcus salivarius SK126	43.226	96.875	0.419
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	42.208	96.25	0.406
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	42.208	96.25	0.406
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	40.506	98.75	0.4
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	41.558	96.25	0.4
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	41.558	96.25	0.4
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	41.558	96.25	0.4
comX	Streptococcus sobrinus strain NIDR 6715-7	41.558	96.25	0.4
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	41.558	96.25	0.4