Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AOY61_RS22230 Genome accession   NZ_CP028766
Coordinates   4524745..4525377 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain A8     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4519745..4530377
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AOY61_RS22205 (AOY61_23640) yheS 4519914..4521827 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  AOY61_RS22210 (AOY61_23645) yheT 4521827..4522849 (+) 1023 WP_000057405.1 hydrolase -
  AOY61_RS22215 (AOY61_23650) yheU 4522843..4523061 (+) 219 WP_000907085.1 YheU family protein -
  AOY61_RS22220 (AOY61_23655) prkB 4523115..4523984 (+) 870 WP_001274680.1 phosphoribulokinase -
  AOY61_RS22225 (AOY61_23660) yhfA 4524039..4524443 (-) 405 WP_001148908.1 OsmC family protein -
  AOY61_RS22230 (AOY61_23670) crp 4524745..4525377 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AOY61_RS22235 (AOY61_23675) yhfK 4525428..4527518 (+) 2091 WP_001345983.1 YccS/YhfK family putative transporter -
  AOY61_RS22240 (AOY61_23680) argD 4527585..4528805 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AOY61_RS22245 (AOY61_23685) pabA 4528891..4529454 (-) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  AOY61_RS22250 (AOY61_23690) fic 4529486..4530088 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  AOY61_RS22255 (AOY61_23695) yhfG 4530078..4530245 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=247943 AOY61_RS22230 WP_000242755.1 4524745..4525377(+) (crp) [Escherichia coli strain A8]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=247943 AOY61_RS22230 WP_000242755.1 4524745..4525377(+) (crp) [Escherichia coli strain A8]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment