Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   TRNA_RS28420 Genome accession   NC_006270
Coordinates   1388261..1389559 (-) Length   432 a.a.
NCBI ID   WP_011197827.1    Uniprot ID   A5A684
Organism   Bacillus licheniformis DSM 13 = ATCC 14580     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1383261..1394559
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TRNA_RS28400 (BL03776) - 1383809..1384693 (+) 885 WP_003180929.1 carbohydrate ABC transporter permease -
  TRNA_RS28405 (BL03743) - 1384731..1386059 (-) 1329 WP_009328706.1 APC family permease -
  TRNA_RS28410 (BL03775) - 1386379..1387332 (+) 954 WP_011197826.1 ring-cleaving dioxygenase -
  TRNA_RS28415 (BL03774) - 1387725..1388087 (+) 363 WP_003180937.1 hypothetical protein -
  TRNA_RS28420 (BL03742) htrA 1388261..1389559 (-) 1299 WP_011197827.1 S1C family serine protease Regulator
  TRNA_RS28425 (BL03773) proG 1389718..1390530 (+) 813 WP_011197828.1 pyrroline-5-carboxylate reductase ProG -
  TRNA_RS28430 (BL03772) - 1390746..1391570 (+) 825 WP_009328702.1 M55 family metallopeptidase -
  TRNA_RS28435 (BL03771) - 1391586..1392512 (+) 927 WP_009328701.1 ABC transporter permease -
  TRNA_RS28440 (BL03770) - 1392517..1393476 (+) 960 WP_009328700.1 ABC transporter permease -
  TRNA_RS28445 (BL03769) - 1393484..1394482 (+) 999 WP_009328699.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 45576.76 Da        Isoelectric Point: 4.7712

>NTDB_id=23884 TRNA_RS28420 WP_011197827.1 1388261..1389559(-) (htrA) [Bacillus licheniformis DSM 13 = ATCC 14580]
MEYNREDQLETKNELIVSDQKPDQAIKKAEQQKRRLSWMTPILSGIIGGSLVLGVTTYQHSKDETANTSVQTQTNETSNS
SASSTKANTEKLSSTNSSDISTMVENVSPAIVGISNYQKQTESGMFGFESNSSSSSEQETGTGSGVIYKKANGKAYIITN
NHVVEGASKLTVSLSNGKEVEGKLLGSDSLTDLAVVEISADHVEKVASFGDSSSLKAGESVIAIGNPLGKDLSRTVTQGI
ISGVDRTVSVDTSAGQTEMNVIQTDAAINPGNSGGALLNTKGEVIGINSMKISESGVEGIGFAIPSNDVKPIAEELMSKG
KIERPFIGIGMMDLEQVPENYQTGTLGLSGSQLNKGVYIRQVASGSPAEKAGLKENDVIVSFNGKETDTGSALRNLLYND
AKIGDTVKVTLIRNGKTMTKQITLDQKESASS

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=23884 TRNA_RS28420 WP_011197827.1 1388261..1389559(-) (htrA) [Bacillus licheniformis DSM 13 = ATCC 14580]
ATGGAATATAATAGAGAAGATCAGCTTGAAACAAAAAACGAACTCATCGTCTCCGATCAAAAGCCCGACCAGGCGATAAA
AAAAGCAGAACAGCAAAAGCGGAGACTCTCGTGGATGACGCCGATTCTCAGCGGCATCATCGGAGGAAGCCTCGTTCTCG
GCGTCACGACATACCAGCATAGCAAAGACGAAACGGCCAATACATCCGTCCAGACGCAAACAAACGAGACGTCGAACTCA
TCGGCTTCTTCCACTAAAGCGAATACCGAAAAATTGTCCAGCACCAATTCGTCCGACATTTCTACAATGGTTGAAAATGT
ATCTCCCGCCATCGTCGGTATTTCAAACTATCAAAAACAAACAGAGAGCGGTATGTTCGGTTTTGAAAGCAACAGCAGCA
GCTCAAGCGAACAAGAAACAGGCACAGGCTCAGGTGTCATCTATAAAAAAGCAAACGGCAAAGCATACATTATTACAAAT
AACCACGTTGTCGAAGGCGCGTCTAAACTGACGGTTTCCCTGTCCAACGGCAAAGAAGTGGAAGGTAAATTGCTGGGCAG
CGATTCGTTGACAGACCTTGCCGTTGTTGAAATTTCCGCTGATCACGTGGAAAAAGTCGCCTCTTTCGGCGATTCGTCAA
GCTTGAAAGCAGGCGAATCGGTGATCGCTATTGGAAACCCGCTCGGCAAAGATCTGTCCCGCACGGTGACACAAGGCATC
ATCAGCGGTGTTGATCGGACCGTTTCCGTAGATACATCCGCAGGCCAAACCGAGATGAACGTCATTCAAACCGACGCGGC
CATCAACCCCGGCAACAGCGGAGGCGCCCTTTTGAATACAAAGGGTGAAGTGATCGGCATCAACAGCATGAAAATCAGTG
AAAGCGGAGTAGAAGGCATCGGATTTGCGATTCCAAGCAATGATGTCAAACCGATTGCAGAAGAGCTGATGTCTAAAGGA
AAAATTGAGCGCCCGTTCATCGGAATCGGCATGATGGATCTTGAGCAGGTGCCGGAAAACTATCAAACAGGCACCCTCGG
ATTAAGCGGCAGCCAGTTAAACAAAGGCGTCTACATCCGCCAGGTCGCTTCAGGCTCCCCAGCTGAAAAAGCGGGCCTTA
AAGAGAACGATGTCATCGTCAGCTTTAACGGAAAAGAAACCGATACAGGAAGCGCGCTGCGCAACCTTCTTTACAACGAT
GCAAAAATCGGGGATACGGTAAAGGTTACCCTCATTCGAAACGGCAAAACCATGACAAAACAAATCACCCTTGACCAGAA
AGAATCCGCATCATCTTAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(327-424)

Trypsin-like peptidase domain (Trypsin_2)

(143-287)

Peptidase family M50 (Peptidase_M50)

(68-429)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A5A684

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

42.04

93.056

0.391
  htrA Streptococcus gordonii str. Challis substr. CH1

38.971

94.444

0.368
  htrA Streptococcus mitis NCTC 12261

43.733

83.102

0.363

Multiple sequence alignment